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ClinicalTrials.gov 4 recruiting now official registry

End Stage Renal Disease (ESRD) clinical trials

4 of 11 indexed End Stage Renal Disease (ESRD) trials are currently recruiting.

11 US clinical trials · 4 currently recruiting

End Stage Renal Disease (ESRD) is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Venova Medical, running 2 of these trials.

The research picture

End Stage Renal Disease (ESRD) has 11 registered US clinical trials, 4 of them open to new participants right now, about 36% of the total.

4
recruiting participants now
36%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
2
top sponsor: Venova Medical
Phase 13Phase 21Phase 31

Active & Recent Trials

11 total, page 1 of 1

RECRUITING Phase 3 150 participants

To Compare the Efficacy and Safety of the ATEV With AVF in Female Patients With End-Stage Renal Disease Requiring Hemodialysis

Humacyte

NCT05908084

RECRUITING 150 participants

EndoForce Post Approval Study

Phraxis

NCT07146854

RECRUITING NA 133 participants

A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease

W.L.Gore & Associates

NCT04671771

RECRUITING NA 126 participants

Pivotal Study of the Velocity™ pAVF System

Venova Medical

NCT07153939

ACTIVE NOT RECRUITING 96 participants

Outcome of BCF Access in Hemodialysis Patients

University of Chicago

NCT01693263

ACTIVE NOT RECRUITING Phase 1 74 participants

Autologous Adipose Derived Mesenchymal Stem Cells (AMSC) in Reducing Hemodialysis Arteriovenous Fistula Failure

Mayo Clinic

NCT02808208

ACTIVE NOT RECRUITING Phase 1 50 participants

TRT as an Adjunctive ERAS Therapy in ESRD Patients Undergoing Kidney Transplantation

University of California, Los Angeles

NCT07287800

ACTIVE NOT RECRUITING Phase 1 32 participants

A Study of Pharmacokinetics and Safety of LY3537031 in Participants With Normal Renal Function and Participants With Renal Impairment

Eli Lilly and Company

NCT07165015

ACTIVE NOT RECRUITING NA 20 participants

Early Feasibility Study of the Velocity™ Percutaneous Arterio-Venous Fistula System for Creating Hemodialysis Vascular Access

Venova Medical

NCT06712251

COMPLETED NA 2,912 participants

Product Evaluation for the Effectiveness of the ClearGuard™ HD End Cap

Pursuit Vascular

NCT02604264

COMPLETED Phase 2 18 participants

A Clinical Trial of Epizon-701 (EPN-701) in Subjects With End-Stage Renal Disease (ESRD)

Epizon Pharma

NCT05285787

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 1
Phase 3 1

Top Sponsors

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the End Stage Renal Disease (ESRD) Trial Landscape

11 indexed End Stage Renal Disease (ESRD) studies · 4 recruiting (36%).

Phase mix: 1 late (III/IV) vs 4 early (I/II).

Top sponsor: Venova Medical (2 trials), 9 others listed. 11 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for End Stage Renal Disease (ESRD)?

PlainTrial tracks 11 US clinical trials for End Stage Renal Disease (ESRD), of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for End Stage Renal Disease (ESRD)?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.