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ClinicalTrials.gov 4 recruiting now early-phase tilt small index

End Stage Renal Disease (ESRD): early-phase trial registry

4 of 11 indexed End Stage Renal Disease (ESRD) trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 4 currently recruiting · #1,577 of 28,707 conditions by registered trial count

End Stage Renal Disease (ESRD): 11 US clinical trials tracked, 4 recruiting.

End Stage Renal Disease (ESRD) is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Venova Medical, running 2 of these trials.

Enrollment posture brief

Registry condition end-stage-renal-disease-esrd

OPEN 4 | RECR 36% | LATE 1 | EARLY 4 | RANK #1577 | SPON 2

Nearest open-share peer: Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive (36% recruiting · 11 trials)

Acute Pancreatitis81.8%Acute Stroke45.5%Acquired Brain Injury36.4%End Stage Renal Disease (thi…36%Acute Lung Injury9.1%
Open-enrollment share among volume-matched conditions near End Stage Renal Disease (ESRD)

End Stage Renal Disease (ESRD) lists 4 open slots (36% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for End Stage Renal Disease (ESRD) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. End Stage Renal Disease (ESRD) is recruiting below its size-band peers.

    4 of 11 indexed trials (36.4%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates End Stage Renal Disease (ESRD) research.

    Venova Medical accounts for 2 of 11 trials (18.2%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical End Stage Renal Disease (ESRD) enrolment sits around 96 participants.

    Median target enrolment is 96 among the 11 trials that report a genuine target (sentinel values excluded). 6 of those (54.5%) plan for fewer than 100 participants.

  4. End Stage Renal Disease (ESRD) research is mostly interventional.

    9 interventional and 2 observational studies make up this index (81.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 21Phase 31

Open and recent trials

11 total, page 1 of 1

RECRUITING Phase 3 150 participants

To Compare the Efficacy and Safety of the ATEV With AVF in Female Patients With End-Stage Renal Disease Requiring Hemodialysis

Humacyte

NCT05908084

RECRUITING 150 participants

EndoForce Post Approval Study

Phraxis

NCT07146854

RECRUITING NA 133 participants

A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease

W.L.Gore & Associates

NCT04671771

RECRUITING NA 126 participants

Pivotal Study of the Velocity™ pAVF System

Venova Medical

NCT07153939

ACTIVE NOT RECRUITING 96 participants

Outcome of BCF Access in Hemodialysis Patients

University of Chicago

NCT01693263

ACTIVE NOT RECRUITING Phase 1 74 participants

Autologous Adipose Derived Mesenchymal Stem Cells (AMSC) in Reducing Hemodialysis Arteriovenous Fistula Failure

Mayo Clinic

NCT02808208

ACTIVE NOT RECRUITING Phase 1 50 participants

TRT as an Adjunctive ERAS Therapy in ESRD Patients Undergoing Kidney Transplantation

University of California, Los Angeles

NCT07287800

ACTIVE NOT RECRUITING Phase 1 32 participants

A Study of Pharmacokinetics and Safety of LY3537031 in Participants With Normal Renal Function and Participants With Renal Impairment

Eli Lilly and Company

NCT07165015

ACTIVE NOT RECRUITING NA 20 participants

Early Feasibility Study of the Velocity™ Percutaneous Arterio-Venous Fistula System for Creating Hemodialysis Vascular Access

Venova Medical

NCT06712251

COMPLETED NA 2,912 participants

Product Evaluation for the Effectiveness of the ClearGuard™ HD End Cap

Pursuit Vascular

NCT02604264

COMPLETED Phase 2 18 participants

A Clinical Trial of Epizon-701 (EPN-701) in Subjects With End-Stage Renal Disease (ESRD)

Epizon Pharma

NCT05285787

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 1
Phase 3 1

Top Sponsors

Named interventions

Most-linked intervention names on End Stage Renal Disease (ESRD) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

EPN-701 (Oral) Drug
1 trials
ClearGuard HD end cap Device
1 trials
brachiocephalic fistula (BCF) Other
1 trials
Velocity pAVF System Device
1 trials
Testosterone Replacement Therapy Drug
1 trials
Two Applications of Adipose Derived Mesenchymal Stem Cells (AMSC) Biological
1 trials
Single Application of Adipose Derived Mesenchymal Stem Cells (AMSC) Biological
1 trials
InnAVasc Arteriovenous Graft (IG) surgical implant Device
1 trials

US sites by state

Facility locations filed on End Stage Renal Disease (ESRD) trials. A trial with sites in several states counts in each.

Florida 5 trials
California 4 trials
Texas 3 trials
Massachusetts 3 trials
Georgia 3 trials
South Carolina 2 trials
New Jersey 2 trials
North Carolina 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this End Stage Renal Disease (ESRD) page

11 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 4 End Stage Renal Disease (ESRD) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Venova Medical sponsors the most End Stage Renal Disease (ESRD) trials on record, review their full trial history before evaluating a specific study. See Venova Medical's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This End Stage Renal Disease (ESRD) condition card totals 11 registered trials; most-linked intervention EPN-701 (Oral); top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.