Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 5 recruiting now full pipeline small index

Dravet Syndrome: full-pipeline trial registry

5 of 13 indexed Dravet Syndrome trials are currently recruiting.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · 5 currently recruiting · #1,315 of 28,707 conditions by registered trial count

Dravet Syndrome: 13 US clinical trials tracked, 5 recruiting.

Dravet Syndrome is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Longboard Pharmaceuticals, running 3 of these trials.

Enrollment posture brief

Registry condition dravet-syndrome

OPEN 5 | RECR 38% | LATE 6 | EARLY 6 | RANK #1315 | SPON 3

Nearest open-share peer: Anaplastic Oligodendroglioma (38% recruiting · 13 trials)

ACL Injury61.5%Acute Biphenotypic Leukemia46.2%Dravet Syndrome (this)38%Accidental Falls30.8%Actinic Keratoses23.1%
Open-enrollment share among volume-matched conditions near Dravet Syndrome

Dravet Syndrome lists 5 open slots (38% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Dravet Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Dravet Syndrome is recruiting below its size-band peers.

    5 of 13 indexed trials (38.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Dravet Syndrome research.

    Longboard Pharmaceuticals accounts for 3 of 13 trials (23.1%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Most Dravet Syndrome trials plan to enrol fewer than 100 people.

    Median target enrolment is 52 among the 13 trials that report a genuine target (sentinel values excluded). 8 of those (61.5%) plan for fewer than 100 participants.

  4. Dravet Syndrome research is mostly interventional.

    12 interventional and 1 observational studies make up this index (92.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 23Phase 35Phase 41

Open and recent trials

13 total, page 1 of 1

RECRUITING Phase 3 170 participants

A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome

Stoke Therapeutics

NCT06872125

RECRUITING Phase 3 160 participants

A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)

Longboard Pharmaceuticals

NCT06660394

RECRUITING Phase 3 150 participants

A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome

Epygenix

NCT04462770

RECRUITING Phase 1 47 participants

A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome

Encoded Therapeutics

NCT05419492

RECRUITING 36 participants

GABA Biomarkers in Dravet Syndrome

Cook Children's Health Care System

NCT05651204

ACTIVE NOT RECRUITING Phase 4 154 participants

Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution

Jazz Pharmaceuticals

NCT05044819

ACTIVE NOT RECRUITING Phase 2 60 participants

An Open-Label Extension Study of STK-001 for Patients With Dravet Syndrome

Stoke Therapeutics

NCT04740476

ACTIVE NOT RECRUITING Phase 3 25 participants

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to Less Than 2 Years of Age With Dravet Syndrome

UCB Biosciences

NCT06118255

COMPLETED Phase 3 412 participants

A Study to Investigate the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution in Children and Adults With Epileptic Encephalopathy Including Dravet Syndrome and Lennox-Gastaut Syndrome

Zogenix

NCT03936777

COMPLETED Phase 1 52 participants

Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies

Longboard Pharmaceuticals

NCT05364021

COMPLETED Phase 2 41 participants

Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy

Longboard Pharmaceuticals

NCT05626634

COMPLETED Phase 1 9 participants

A Study to Assess the Safety and Tolerability of ZX008 in Children and Young Adults With Dravet Syndrome or Lennox Gastaut Syndrome Currently Taking Cannabidiol

Zogenix International Limited, Inc., a subsidiary of Zogenix

NCT03467113

COMPLETED Phase 2 2 participants

Verapamil as Therapy for Children and Young Adults With Dravet Syndrome

Gillette Children's Specialty Healthcare

NCT01607073

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 3
Phase 3 5
Phase 4 1

Named interventions

Most-linked intervention names on Dravet Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
3 trials
LP352 Drug
2 trials
Cannabidiol Drug
2 trials
LP352, bexicaserin Drug
1 trials
ZX008 0.2 to 0.8 mg/kg/day Drug
1 trials
zorevunersen (STK-001) Drug
1 trials
Verapamil Drug
1 trials
ZX008 (Fenfluramine Hydrochloride) Drug
1 trials

US sites by state

Facility locations filed on Dravet Syndrome trials. A trial with sites in several states counts in each.

Illinois 9 trials
Florida 9 trials
California 9 trials
New York 8 trials
Minnesota 7 trials
Texas 5 trials
Michigan 5 trials
Maryland 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Dravet Syndrome page

13 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Dravet Syndrome condition card totals 13 registered trials; most-linked intervention Placebo; top US site state Illinois. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.