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COMPLETED Phase 1

Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies

NCT05364021 · View on ClinicalTrials.gov ↗

Study Summary

The objective of this study is to assess the safety, tolerability, efficacy, and pharmacokinetics of adjunctive therapy of LP352 in adults and adolescents with developmental and epileptic encephalopathies.

Interventions

  • DRUG Placebo
  • DRUG LP352

Study Locations (20)

Florida

  • Northwest Florida Clinical Research Group — Gulf Breeze
  • University of Miami — Miami
  • Advent Health Orlando — Orlando
  • Research Institute of Orlando — Orlando
  • University of South Florida — Tampa

California

  • Rancho Los Amigos National Rehabilitation Center (RLANRC) — Downey
  • Children's Hospital of Orange County — Orange
  • University of California San Francisco — San Francisco

New York

  • Boston Children's Health Physicians LLP — Hawthorne
  • New York University Langone Hospital - Long Island — Mineola
  • Northwell Health — New York

Arizona

  • University of Arizona - Health Sciences Center — Tucson

Arkansas

  • Arkansas Children's Hospital — Little Rock

Hawaii

  • Hawaii Pacific Neuroscience — Honolulu

Idaho

  • Consultants in Epilepsy and Neurology — Boise

Illinois

  • Northwestern University Feinberg School of Medicine — Chicago

Trial Details

FieldValue
Enrollment Target 52 participants
Start Date 2022-03-03
Est. Completion 2023-11-20
Phase Phase 1

Sponsor

Longboard Pharmaceuticals

4 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05364021

The ClinicalTrials.gov registry entry for NCT05364021 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 52 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Longboard Pharmaceuticals, which has 4 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Dravet Syndrome appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05364021 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Florida, California, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05364021 about?

NCT05364021 is a clinical study titled "Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies". The objective of this study is to assess the safety, tolerability, efficacy, and pharmacokinetics of adjunctive therapy of LP352 in adults and adolescents with developmental and epileptic encephalopathies.

What is the current status of trial NCT05364021?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 52 participants. The study started on 2022-03-03. Estimated completion is 2023-11-20.

What conditions does trial NCT05364021 study?

This clinical trial studies the following conditions: Dravet Syndrome, Lennox Gastaut Syndrome, Developmental and Epileptic Encephalopathy. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05364021?

The interventions under investigation include: Placebo (DRUG), LP352 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05364021?

This trial is sponsored by Longboard Pharmaceuticals, which has 4 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05364021 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California, Florida, Hawaii. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial