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ClinicalTrials.gov official registry

Diabetic Foot Ulcers clinical trials

All 13 indexed Diabetic Foot Ulcers trials have closed enrollment.

13 US clinical trials ·

Diabetic Foot Ulcers is the subject of 13 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 2 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is US Department of Veterans Affairs, running 2 of these trials.

The research picture

Diabetic Foot Ulcers has 13 registered US clinical trials; none are currently listed as recruiting, so most are completed or in follow-up.

0
recruiting participants now
0%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
2
top sponsor: US Department of Veterans Affairs
Phase 12Phase 23Phase 31Phase 41

Active & Recent Trials

13 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 1 100 participants

Wound Healing Endpoint and Recurrence

Sashwati Roy

NCT02577120

ACTIVE NOT RECRUITING Phase 2 90 participants

Phase II Study to Evaluate Efficacy and Safety of AMP Peptide PL-5 in Mild Infections of Diabetic Foot Ulcers

Jiangsu ProteLight Pharmaceutical & Biotechnology Co.

NCT06189638

COMPLETED 750 participants

A Prospective Study of Endothelial Dysfunction and Diabetic Foot Ulcer Risk

US Department of Veterans Affairs

NCT00013286

COMPLETED Phase 3 584 participants

MSI-78 Topical Cream vs. Oral Ofloxacin in the Treatment of Infected Diabetic Ulcers

Abeona Therapeutics

NCT00563394

COMPLETED Phase 2 427 participants

Clinical Trials of Footwear in Patients With Diabetes-Study Arm 2,3

US Department of Veterans Affairs

NCT00013299

COMPLETED 256 participants

Hyperspectral Imaging to Assess and Predict Diabetic Foot Ulcers

HyperMed

NCT00617916

COMPLETED NA 225 participants

Instant Total Contact Cast to Heal Diabetic Foot Ulcers

University of Texas Southwestern Medical Center

NCT01221207

COMPLETED Phase 2 168 participants

A Study to Investigate the Safety and Clinical Effect of Nexagon® as a Topical Treatment for Subjects With a Diabetic Foot Ulcer (DUNE)

OcuNexus Therapeutics

NCT01490879

COMPLETED 70 participants

UT Southwestern Diabetic Foot Ulcers (DFU) and Osteomyelitis (DFO) Recruitment Database, Data and Tissue Repository

University of Texas Southwestern Medical Center

NCT02463500

COMPLETED Phase 4 57 participants

A Study to Look at the Effects of Four Weeks of Treatment on the Healing of Diabetic Foot Ulcers

Healthpoint

NCT01143714

COMPLETED 38 participants

Non-Invasive Assessment of Wound Healing With Optical Methods

Drexel University College of Medicine

NCT00578604

COMPLETED NA 33 participants

Evaluating the Ease of Use of a VAC GranuFoam Bridge Dressing on Diabetic Foot Ulcers Receiving VAC Negative Pressure Wound Therapy

KCI USA

NCT00847730

COMPLETED Phase 1 16 participants

Safety Study to Examine the Systemic Exposure of Granexin® Gel After Topical Application to Diabetic Foot Ulcers

Xequel Bio

NCT02652754

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 3
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Diabetic Foot Ulcers Trial Landscape

13 indexed Diabetic Foot Ulcers studies · 0 recruiting (0%).

Phase mix: 2 late (III/IV) vs 5 early (I/II).

Top sponsor: US Department of Veterans Affairs (2 trials), 9 others listed. 13 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Diabetic Foot Ulcers?

PlainTrial tracks 13 US clinical trials for Diabetic Foot Ulcers, of which 0 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Diabetic Foot Ulcers?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.