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ClinicalTrials.gov enrollment closed early-phase tilt small index

Diabetic Foot Ulcers: early-phase trial registry

A small indexed set (13 trials) with no open enrollment listed right now.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · none currently recruiting · #1,315 of 28,707 conditions by registered trial count

Diabetic Foot Ulcers: 13 US clinical trials tracked, none currently recruiting.

Diabetic Foot Ulcers is the subject of 13 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 2 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is US Department of Veterans Affairs, running 2 of these trials.

Enrollment posture brief

Registry condition diabetic-foot-ulcers

OPEN 0 | RECR 0% | LATE 2 | EARLY 5 | RANK #1315 | SPON 2

Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia (0% recruiting · 12 trials)

ACL Injury61.5%Acute Biphenotypic Leukemia46.2%Accidental Falls30.8%Actinic Keratoses23.1%Diabetic Foot Ulcers (this)0%
Open-enrollment share among volume-matched conditions near Diabetic Foot Ulcers

Diabetic Foot Ulcers has no open enrollment in this registry pull (13 archived studies). Peers show how other volume-matched labels compare on open share. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Diabetic Foot Ulcers on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Diabetic Foot Ulcers is recruiting below its size-band peers.

    0 of 13 indexed trials (0%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Diabetic Foot Ulcers research.

    US Department of Veterans Affairs accounts for 2 of 13 trials (15.4%). 11 distinct sponsors appear on at least one study for this condition label.

  3. Typical Diabetic Foot Ulcers enrolment sits around 100 participants.

    Median target enrolment is 100 among the 13 trials that report a genuine target (sentinel values excluded). 6 of those (46.2%) plan for fewer than 100 participants.

  4. Diabetic Foot Ulcers splits between interventional and observational designs.

    9 interventional and 4 observational studies make up this index (69.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 23Phase 31Phase 41

Indexed trials (enrollment closed)

13 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 1 100 participants

Wound Healing Endpoint and Recurrence

Sashwati Roy

NCT02577120

ACTIVE NOT RECRUITING Phase 2 90 participants

Phase II Study to Evaluate Efficacy and Safety of AMP Peptide PL-5 in Mild Infections of Diabetic Foot Ulcers

Jiangsu ProteLight Pharmaceutical & Biotechnology Co.

NCT06189638

COMPLETED 750 participants

A Prospective Study of Endothelial Dysfunction and Diabetic Foot Ulcer Risk

US Department of Veterans Affairs

NCT00013286

COMPLETED Phase 3 584 participants

MSI-78 Topical Cream vs. Oral Ofloxacin in the Treatment of Infected Diabetic Ulcers

Abeona Therapeutics

NCT00563394

COMPLETED Phase 2 427 participants

Clinical Trials of Footwear in Patients With Diabetes-Study Arm 2,3

US Department of Veterans Affairs

NCT00013299

COMPLETED 256 participants

Hyperspectral Imaging to Assess and Predict Diabetic Foot Ulcers

HyperMed

NCT00617916

COMPLETED NA 225 participants

Instant Total Contact Cast to Heal Diabetic Foot Ulcers

University of Texas Southwestern Medical Center

NCT01221207

COMPLETED Phase 2 168 participants

A Study to Investigate the Safety and Clinical Effect of Nexagon® as a Topical Treatment for Subjects With a Diabetic Foot Ulcer (DUNE)

OcuNexus Therapeutics

NCT01490879

COMPLETED 70 participants

UT Southwestern Diabetic Foot Ulcers (DFU) and Osteomyelitis (DFO) Recruitment Database, Data and Tissue Repository

University of Texas Southwestern Medical Center

NCT02463500

COMPLETED Phase 4 57 participants

A Study to Look at the Effects of Four Weeks of Treatment on the Healing of Diabetic Foot Ulcers

Healthpoint

NCT01143714

COMPLETED 38 participants

Non-Invasive Assessment of Wound Healing With Optical Methods

Drexel University College of Medicine

NCT00578604

COMPLETED NA 33 participants

Evaluating the Ease of Use of a VAC GranuFoam Bridge Dressing on Diabetic Foot Ulcers Receiving VAC Negative Pressure Wound Therapy

KCI USA

NCT00847730

COMPLETED Phase 1 16 participants

Safety Study to Examine the Systemic Exposure of Granexin® Gel After Topical Application to Diabetic Foot Ulcers

Xequel Bio

NCT02652754

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 3
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Diabetic Foot Ulcers records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Nexagon® vehicle Drug
1 trials
Nexagon® High Dose Drug
1 trials
Nexagon® Medium Dose Drug
1 trials
Nexagon® Low Dose Drug
1 trials
DFU Other
1 trials
White Petrolatum Other
1 trials
Santyl Drug
1 trials
V.A.C. Negative Pressure Wound Therapy System Device
1 trials

US sites by state

Facility locations filed on Diabetic Foot Ulcers trials. A trial with sites in several states counts in each.

Texas 5 trials
Pennsylvania 5 trials
California 4 trials
Washington 3 trials
Florida 3 trials
Arizona 2 trials
Virginia 1 trials
South Carolina 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Diabetic Foot Ulcers page

13 registered trials, 0 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • No Diabetic Foot Ulcers trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • US Department of Veterans Affairs sponsors the most Diabetic Foot Ulcers trials on record, review their full trial history before evaluating a specific study. See US Department of Veterans Affairs's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Diabetic Foot Ulcers condition card totals 13 registered trials; most-linked intervention Nexagon® vehicle; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.