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ClinicalTrials.gov 12 recruiting now official registry

Dermatomyositis clinical trials

Every US clinical trial registered for Dermatomyositis — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

20 US clinical trials · 12 currently recruiting

The research picture

Dermatomyositis has 20 registered US clinical trials, 12 of them open to new participants right now — about 60% of the total.

12
recruiting participants now
60%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
2
top sponsor: argenx

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 5,000 participants

Rheumatology Patient Registry and Biorepository

Yale University

NCT04402086

RECRUITING 1,200 participants

Adult and Juvenile Myositis

National Institute of Environmental Health Sciences (NIEHS)

NCT00017914

RECRUITING 700 participants

MIHRA - Patient-Rooted Insights for Shaping Myositis Science (PRISMS)

Myositis International Health & Research Collaborative Alliance Foundation

NCT07374107

RECRUITING 580 participants

Environmental Risk Factors for the Anti-synthetase Syndrome

National Institute of Environmental Health Sciences (NIEHS)

NCT01276470

RECRUITING Phase 1 300 participants

Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer

National Cancer Institute (NCI)

NCT03816345

RECRUITING 300 participants

Clinical Responsiveness of Dermatomyositis Using Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI)

University of Pennsylvania

NCT02945345

RECRUITING Phase 3 211 participants

A Study to Understand How the Study Medicine Dazukibart Works in People With Idiopathic Inflammatory Myopathies

Pfizer

NCT06698796

RECRUITING Phase 2 74 participants

RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy

Cabaletta Bio

NCT06154252

RECRUITING 70 participants

A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101

Kyverna Therapeutics

NCT07403188

RECRUITING Phase 1 21 participants

Study of KYV-101 Anti-CD19 CAR T Therapy in Adult Dermatomyositis

Stanford University

NCT06298019

RECRUITING Phase 2 20 participants

Intralesional Injection of STS in Treatment of Calcinosis

Robyn T. Domsic, MD, MPH

NCT06672822

RECRUITING Phase 2 15 participants

Topical Ruxolitinib Cream for Refractory Cutaneous Dermatomyositis

The Cleveland Clinic

NCT06857240

ACTIVE NOT RECRUITING Phase 2 265 participants

A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy.

argenx

NCT05523167

ACTIVE NOT RECRUITING Phase 3 241 participants

A Study to Investigate the Efficacy and Safety of Brepocitinib in Adults With Dermatomyositis

Priovant Therapeutics

NCT05437263

ACTIVE NOT RECRUITING Phase 2 40 participants

A Study Evaluating the Effects of GLPG3667 Given as Oral Treatment for up to 24 Weeks in Adults With Dermatomyositis

Galapagos

NCT05695950

ACTIVE NOT RECRUITING Phase 2 3 participants

A Study to Evaluate Safety and Efficacy of Empasiprubart in Adults With Dermatomyositis

argenx

NCT06284954

COMPLETED Phase 3 95 participants

Study Evaluating Efficacy and Safety of Octagam 10% in Patients With Dermatomyositis (Idiopathic Inflammatory Myopathy)

Octapharma

NCT02728752

COMPLETED Phase 2 36 participants

Tocilizumab in the Treatment of Refractory Polymyositis and Dermatomyositis

Chester Oddis

NCT02043548

COMPLETED Phase 2 24 participants

An Extension Study for Participants Who Have Completed the Treatment Period of a Qualifying Parent Study

Pfizer

NCT05192200

COMPLETED Phase 2 20 participants

Methimazole to Treat Polymyositis and Dermatomyositis

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT00001421

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 9
Phase 3 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Dermatomyositis Trial Landscape

ClinicalTrials.gov lists 20 US studies indexed under Dermatomyositis, and 12 of those are currently open to recruitment — roughly 60% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Dermatomyositis shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 11 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Dermatomyositis is led by argenx with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 20 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Dermatomyositis?

PlainTrial tracks 20 US clinical trials for Dermatomyositis, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Dermatomyositis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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