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Dermatomyositis clinical trials
12 of 20 indexed Dermatomyositis trials are currently recruiting.
20 US clinical trials · 12 currently recruiting
Dermatomyositis is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 11 in Phase 1-2 (earlier-stage). The most active sponsor is argenx, running 2 of these trials.
The research picture
Dermatomyositis has 20 registered US clinical trials, 12 of them open to new participants right now, about 60% of the total.
- 12
- recruiting participants now
- 60%
- of trials open to enrollment
- 3
- in Phase 3–4 (later-stage)
- 2
- top sponsor: argenx
Active & Recent Trials
20 total, page 1 of 1
Rheumatology Patient Registry and Biorepository
Yale University
NCT04402086
Adult and Juvenile Myositis
National Institute of Environmental Health Sciences (NIEHS)
NCT00017914
MIHRA - Patient-Rooted Insights for Shaping Myositis Science (PRISMS)
Myositis International Health & Research Collaborative Alliance Foundation
NCT07374107
Environmental Risk Factors for the Anti-synthetase Syndrome
National Institute of Environmental Health Sciences (NIEHS)
NCT01276470
Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer
National Cancer Institute (NCI)
NCT03816345
Clinical Responsiveness of Dermatomyositis Using Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI)
University of Pennsylvania
NCT02945345
A Study to Understand How the Study Medicine Dazukibart Works in People With Idiopathic Inflammatory Myopathies
Pfizer
NCT06698796
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy
Cabaletta Bio
NCT06154252
A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
Kyverna Therapeutics
NCT07403188
Study of KYV-101 Anti-CD19 CAR T Therapy in Adult Dermatomyositis
Stanford University
NCT06298019
Intralesional Injection of STS in Treatment of Calcinosis
Robyn T. Domsic, MD, MPH
NCT06672822
Topical Ruxolitinib Cream for Refractory Cutaneous Dermatomyositis
The Cleveland Clinic
NCT06857240
A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy.
argenx
NCT05523167
A Study to Investigate the Efficacy and Safety of Brepocitinib in Adults With Dermatomyositis
Priovant Therapeutics
NCT05437263
A Study Evaluating the Effects of GLPG3667 Given as Oral Treatment for up to 24 Weeks in Adults With Dermatomyositis
Galapagos
NCT05695950
A Study to Evaluate Safety and Efficacy of Empasiprubart in Adults With Dermatomyositis
argenx
NCT06284954
Study Evaluating Efficacy and Safety of Octagam 10% in Patients With Dermatomyositis (Idiopathic Inflammatory Myopathy)
Octapharma
NCT02728752
Tocilizumab in the Treatment of Refractory Polymyositis and Dermatomyositis
Chester Oddis
NCT02043548
An Extension Study for Participants Who Have Completed the Treatment Period of a Qualifying Parent Study
Pfizer
NCT05192200
Methimazole to Treat Polymyositis and Dermatomyositis
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NCT00001421
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 9 |
| Phase 3 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Dermatomyositis Trial Landscape
20 indexed Dermatomyositis studies · 12 recruiting (60%).
Phase mix: 3 late (III/IV) vs 11 early (I/II).
Top sponsor: argenx (2 trials), 9 others listed. 20 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Dermatomyositis?
PlainTrial tracks 20 US clinical trials for Dermatomyositis, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Dermatomyositis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.