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ClinicalTrials.gov 12 recruiting now early-phase tilt

Dermatomyositis: early-phase trial registry

12 of 20 indexed Dermatomyositis trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #848 of 28,707 conditions by registered trial count.

20 US clinical trials · 12 currently recruiting · #848 of 28,707 conditions by registered trial count

Dermatomyositis: 20 US clinical trials tracked, 12 recruiting.

Dermatomyositis is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 11 in Phase 1-2 (earlier-stage). The most active sponsor is argenx, running 2 of these trials.

Enrollment posture brief

Registry condition dermatomyositis

OPEN 12 | RECR 60% | LATE 3 | EARLY 11 | RANK #848 | SPON 2

Nearest open-share peer: Abuse, Drug (60% recruiting · 5 trials)

Dermatomyositis (this)60%Advanced or Metastatic Solid55%ALS50%Abdominal Pain25%Acute Myocardial Infarction25%
Open-enrollment share among volume-matched conditions near Dermatomyositis

Dermatomyositis lists 12 open slots (60% of 20 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Dermatomyositis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Dermatomyositis is recruiting above its size-band peers.

    12 of 20 indexed trials (60%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Dermatomyositis trials is spread across many organizations.

    argenx accounts for 2 of 20 trials (10%). 17 distinct sponsors appear on at least one study for this condition label.

  3. Typical Dermatomyositis enrolment sits around 95 participants.

    Median target enrolment is 95 among the 20 trials that report a genuine target (sentinel values excluded). 11 of those (55%) plan for fewer than 100 participants.

  4. Dermatomyositis research is mostly interventional.

    14 interventional and 6 observational studies make up this index (70% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 29Phase 33

Open and recent trials

20 total, page 1 of 1

RECRUITING 5,000 participants

Rheumatology Patient Registry and Biorepository

Yale University

NCT04402086

RECRUITING 1,200 participants

Adult and Juvenile Myositis

National Institute of Environmental Health Sciences (NIEHS)

NCT00017914

RECRUITING 700 participants

MIHRA - Patient-Rooted Insights for Shaping Myositis Science (PRISMS)

Myositis International Health & Research Collaborative Alliance Foundation

NCT07374107

RECRUITING 580 participants

Environmental Risk Factors for the Anti-synthetase Syndrome

National Institute of Environmental Health Sciences (NIEHS)

NCT01276470

RECRUITING Phase 1 300 participants

Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer

National Cancer Institute (NCI)

NCT03816345

RECRUITING 300 participants

Clinical Responsiveness of Dermatomyositis Using Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI)

University of Pennsylvania

NCT02945345

RECRUITING Phase 3 211 participants

A Study to Understand How the Study Medicine Dazukibart Works in People With Idiopathic Inflammatory Myopathies

Pfizer

NCT06698796

RECRUITING Phase 2 74 participants

RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy

Cabaletta Bio

NCT06154252

RECRUITING 70 participants

A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101

Kyverna Therapeutics

NCT07403188

RECRUITING Phase 1 21 participants

Study of KYV-101 Anti-CD19 CAR T Therapy in Adult Dermatomyositis

Stanford University

NCT06298019

RECRUITING Phase 2 20 participants

Intralesional Injection of STS in Treatment of Calcinosis

Robyn T. Domsic, MD, MPH

NCT06672822

RECRUITING Phase 2 15 participants

Topical Ruxolitinib Cream for Refractory Cutaneous Dermatomyositis

The Cleveland Clinic

NCT06857240

ACTIVE NOT RECRUITING Phase 2 265 participants

A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy.

argenx

NCT05523167

ACTIVE NOT RECRUITING Phase 3 241 participants

A Study to Investigate the Efficacy and Safety of Brepocitinib in Adults With Dermatomyositis

Priovant Therapeutics

NCT05437263

ACTIVE NOT RECRUITING Phase 2 40 participants

A Study Evaluating the Effects of GLPG3667 Given as Oral Treatment for up to 24 Weeks in Adults With Dermatomyositis

Galapagos

NCT05695950

ACTIVE NOT RECRUITING Phase 2 3 participants

A Study to Evaluate Safety and Efficacy of Empasiprubart in Adults With Dermatomyositis

argenx

NCT06284954

COMPLETED Phase 3 95 participants

Study Evaluating Efficacy and Safety of Octagam 10% in Patients With Dermatomyositis (Idiopathic Inflammatory Myopathy)

Octapharma

NCT02728752

COMPLETED Phase 2 36 participants

Tocilizumab in the Treatment of Refractory Polymyositis and Dermatomyositis

Chester Oddis

NCT02043548

COMPLETED Phase 2 24 participants

An Extension Study for Participants Who Have Completed the Treatment Period of a Qualifying Parent Study

Pfizer

NCT05192200

COMPLETED Phase 2 20 participants

Methimazole to Treat Polymyositis and Dermatomyositis

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT00001421

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 9
Phase 3 3

Named interventions

Most-linked intervention names on Dermatomyositis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
2 trials
methimazole Drug
1 trials
Octagam 10% Drug
1 trials
Anti-Beta Interferon (PF-06823859) Drug
1 trials
tocilizumab Drug
1 trials
PBO Other
1 trials
EFG PH20 SC Biological
1 trials
GLPG3667 Drug
1 trials

US sites by state

Facility locations filed on Dermatomyositis trials. A trial with sites in several states counts in each.

California 10 trials
Florida 8 trials
Pennsylvania 7 trials
Kansas 7 trials
Georgia 6 trials
New York 5 trials
Minnesota 5 trials
Arizona 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Dermatomyositis page

20 registered trials, 12 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 12 Dermatomyositis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • argenx sponsors the most Dermatomyositis trials on record, review their full trial history before evaluating a specific study. See argenx's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Dermatomyositis condition card totals 20 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.