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ACTIVE NOT RECRUITING Phase 2

A Study Evaluating the Effects of GLPG3667 Given as Oral Treatment for up to 24 Weeks in Adults With Dermatomyositis

NCT05695950 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to evaluate the efficacy, safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of orally administered GLPG3667 once daily for 24 weeks in adult participants with dermatomyositis (DM), followed by an open-label extension (OLE) period until Week 48.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG GLPG3667

Study Locations (20)

Other

  • Fundacion Respirar Consultorios Médicos Dr. Doreski — Buenos Aires
  • Hospital Cordoba — Córdoba
  • Hospital Italiano de La Plata — La Plata
  • Framingham Centro Medico — La Plata
  • Instituto Medico CER — Quilmes
  • UZ Leuven — Leuven
  • Enroll SpA — Santiago
  • BioMedica Research Group Psicomedica Clinical and Research Group — Santiago
  • Clinica de la Costa S.A.S — Barranquilla
  • Centro de Investigacion Medico Asistencial S.A.S — Barranquilla
  • Healthy Medical Center — Zipaquirá
  • Polyclinic Bonifarm — Zagreb

Florida

  • New Access Research and Medical Center — Kendall
  • Omega Research Orlando, LLC — Orlando

Arizona

  • HonorHealth Neurology — Scottsdale

California

  • Inland Rheumatology Clinical Trials, Inc. — Upland

Georgia

  • Augusta University — Augusta

Minnesota

  • St. Paul Rheumatology — Eagan

New York

  • Northwell Health, LLC PRIME — Lake Success

Pennsylvania

  • Altoona Center for Clinical Research, P.C. — Duncansville

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2023-02-27
Est. Completion 2026-04
Phase Phase 2

Sponsor

Galapagos

7 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05695950

The ClinicalTrials.gov registry entry for NCT05695950 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Galapagos, which has 7 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Dermatomyositis appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05695950 reports 20 study locations spanning 8 distinct geographic areas — top geographies include Other, Florida, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05695950 about?

NCT05695950 is a clinical study titled "A Study Evaluating the Effects of GLPG3667 Given as Oral Treatment for up to 24 Weeks in Adults With Dermatomyositis". The purpose of this study is to evaluate the efficacy, safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of orally administered GLPG3667 once daily for 24 weeks in adult participants with dermatomyositis (DM), followed by an open-label extension (OLE) period until Week 48.

What is the current status of trial NCT05695950?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2023-02-27. Estimated completion is 2026-04.

What conditions does trial NCT05695950 study?

This clinical trial studies the following conditions: Dermatomyositis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05695950?

The interventions under investigation include: Placebo (DRUG), GLPG3667 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05695950?

This trial is sponsored by Galapagos, which has 7 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05695950 being conducted?

This trial has 20 study locations across Arizona, California, Florida, Georgia, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial