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2026 data Public-data reference. official source

DCIS

Open-data reference.

10 US clinical trials · 6 currently recruiting

Active & Recent Trials

RECRUITING 3,000 participants

The PREDICT Registry:

PreludeDx

NCT03448926

RECRUITING Phase 3 500 participants

Delayed Sentinel Lymph Node Biopsy in Ductal Cancer in Situ

Uppsala University

NCT04722692

RECRUITING Phase 2 280 participants

Study of 3-Day Partial Breast Radiation Therapy in Women With Breast Cancer

Memorial Sloan Kettering Cancer Center

NCT04084730

RECRUITING Phase 2 90 participants

Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-Stage Breast Cancer (H-ASSIST)

UNC Lineberger Comprehensive Cancer Center

NCT06902311

RECRUITING Phase 2 30 participants

Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer

University of Wisconsin, Madison

NCT03936478

RECRUITING NA 24 participants

Perioperative Mindfulness Proposal

Hoag Memorial Hospital Presbyterian

NCT04049214

ACTIVE NOT RECRUITING NA 997 participants

Comparing an Operation to Monitoring, With or Without Endocrine Therapy (COMET) Trial For Low Risk DCIS

Alliance Foundation Trials

NCT02926911

ACTIVE NOT RECRUITING Phase 1 100 participants

LS301-IT in Partial Mastectomy and Sentinel Lymph Node Biopsy (SLNB) for DCIS or Stage I-II Primary Invasive Breast Cancer

Integro Theranostics

NCT05900986

COMPLETED Phase 1 58 participants

DC Vaccine for Patients With Ductal Carcinoma In Situ

Abramson Cancer Center at Penn Medicine

NCT02061332

COMPLETED Phase 2 42 participants

Chemoprevention Trial - Anastrozole in Ductal Carcinoma In Situ (DCIS) in Postmenopausal Women

Rita Sanghvi, Mehta

NCT00256217

Phase Distribution

PhaseTrial count
Early Phase 1 2
Phase 2 4
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the DCIS Trial Landscape

ClinicalTrials.gov lists 10 US studies indexed under DCIS, and 6 of those are currently open to recruitment — roughly 60% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for DCIS shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for DCIS is led by Rita Sanghvi, Mehta with 1 indexed trial, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 10 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for DCIS?

PlainTrial tracks 10 US clinical trials for DCIS, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for DCIS?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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