Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02926911 · ClinicalTrials.gov registry record · NA
Comparing an Operation to Monitoring, With or Without Endocrine Therapy (COMET) Trial For Low Risk DCIS
A NA study of Ductal Carcinoma In Situ and DCIS, sponsored by Alliance Foundation Trials.
- Active
- Registry status
- NA
- Development phase
- 997
- Enrollment target
- 20
- Study locations
NCT02926911 is a NA study of Ductal Carcinoma In Situ and DCIS that is active but no longer recruiting, run by Alliance Foundation Trials. The registered enrollment target is 997 participants, above the 191-participant average among 15 other Ductal Carcinoma In Situ trials with a reported enrollment target (422% higher). The trial reports 20 study locations across 10 states.
The verdict
NCT02926911, a NA study of Ductal Carcinoma In Situ and DCIS, is active but no longer recruiting, sponsored by Alliance Foundation Trials.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 997 participants
- Enrollment target
- 20
- Study locations
Study Summary
This study looks at the risks and benefits of active monitoring (AM) compared to surgery in the setting of a pragmatic prospective randomized trial for low risk DCIS. Our overarching hypothesis is that management of low-risk Ductal Carcinoma in Situ (DCIS) using an AM approach does not yield inferior cancer or quality of life outcomes compared to surgery.
Conditions Studied
Interventions
- OTHER Surgery
- OTHER Active Monitoring
Study Locations (20)
Illinois
- John H Stroger Jr Hospital of Cook County - Chicago
- University of Chicago Medical Center - Chicago
- Advocate Illinois Masonic Medical Center - Chicago
- NorthShore University HealthSystem-Evanston Hospital - Evanston
- Ingalls Memorial Hospital - Harvey
- Illinois Cancer Care - Peoria
California
- City of Hope - Duarte
- Cedars-Sinai Medical Center - Los Angeles
- Sharp Memorial Hospital - San Diego
- Kaiser Permanente Medical Center - Vallejo
Colorado
- Colorado Cancer Research Program - Denver
- Saint Joseph Hospital- Cancer Centers of Colorado - Lafayette
Florida
- Memorial Healthcare System - Hollywood
- Mayo Clinic Florida - Jacksonville
Alaska
- Providence Alaska Medical Center - Anchorage
Arizona
- Mayo Clinic - Phoenix
Connecticut
- Smilow Cancer Hospital at Yale-New Haven - New Haven
District of Columbia
- MedStar Washington Hospital Center - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 997 participants |
| Start Date | 2017-02-22 |
| Est. Completion | 2030-07 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02926911
The ClinicalTrials.gov registry entry for NCT02926911 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 997 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 191-participant average among 15 other Ductal Carcinoma In Situ trials with a reported enrollment target (422% higher). The listed sponsor is Alliance Foundation Trials, which has 20 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Ductal Carcinoma In Situ appearing as the primary indexed condition, and to 2 interventions - of which Surgery is the first listed.
NCT02926911 reports 20 study locations spanning 10 distinct geographic areas - top geographies include Illinois, California, Colorado.
Frequently Asked Questions
What is clinical trial NCT02926911 about?
NCT02926911 is a clinical study titled "Comparing an Operation to Monitoring, With or Without Endocrine Therapy (COMET) Trial For Low Risk DCIS". This study looks at the risks and benefits of active monitoring (AM) compared to surgery in the setting of a pragmatic prospective randomized trial for low risk DCIS. Our overarching hypothesis is that management of low-risk Ductal Carcinoma in Situ (DCIS) using an AM approach does not yield inferio...
What is the current status of trial NCT02926911?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 997 participants. The study started on 2017-02-22. Estimated completion is 2030-07.
What conditions does trial NCT02926911 study?
This clinical trial studies the following conditions: Ductal Carcinoma In Situ, DCIS.
What interventions are being tested in trial NCT02926911?
The interventions under investigation include: Surgery (OTHER), Active Monitoring (OTHER).
Who is sponsoring clinical trial NCT02926911?
This trial is sponsored by Alliance Foundation Trials, which has 20 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02926911 being conducted?
This trial has 20 study locations across Alaska, Arizona, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Ductal Carcinoma In Situ
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Cryoablation as a Minimally Invasive Alternative to Surgery for Managing Ductal Carcinoma In Situ
RECRUITING · NA
-
A Study of Disappearing Markers for Daily Radiation Treatment Delivery for Breast Cancer Patients.
RECRUITING · NA
-
Novel Cavity Marking Technique in Breast Cancer Patients Undergoing Breast Conservation Surgery With Oncoplastic Reconstruction for the Delivery of Adjuvant Radiotherapy and Accuracy of Recommended Re-excisions
RECRUITING · NA
-
Safety and Efficacy Study of the Xoft® Axxent® eBx® IORT System®
ACTIVE NOT RECRUITING · NA
-
Intraoperative Radiation Therapy (IORT) in DCIS
ACTIVE NOT RECRUITING · NA
-
Living Well After Breast Surgery
COMPLETED · NA
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.