Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Cushing's Syndrome: early-phase trial registry
2 of 6 indexed Cushing's Syndrome trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,866 of 28,707 conditions by registered trial count.
6 US clinical trials · 2 currently recruiting · #2,866 of 28,707 conditions by registered trial count
Cushing's Syndrome: 6 US clinical trials tracked, 2 recruiting.
Cushing's Syndrome is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), running 2 of these trials.
Enrollment posture brief
Registry condition cushings-syndrome
OPEN 2 | RECR 33% | LATE 0 | EARLY 3 | RANK #2866 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Adherence, Treatment (33% recruiting · 6 trials)
Cushing's Syndrome lists 2 open slots (33% of 6 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Cushing's Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Cushing's Syndrome is recruiting below its size-band peers.
2 of 6 indexed trials (33.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Cushing's Syndrome research.
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) accounts for 2 of 6 trials (33.3%). 5 distinct sponsors appear on at least one study for this condition label.
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Most Cushing's Syndrome trials plan to enrol fewer than 100 people.
Median target enrolment is 80 among the 6 trials that report a genuine target (sentinel values excluded). 4 of those (66.7%) plan for fewer than 100 participants.
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Cushing's Syndrome splits between interventional and observational designs.
3 interventional and 3 observational studies make up this index (50% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
6 total, page 1 of 1
Prospective Evaluation of 68Ga-DOTATATE PET/CT, Octreotide and F-DOPA PET Imaging in Ectopic Cushing Syndrome
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT02019706
Evaluating the Functional Status of the Adrenal Glands With [68Ga]Ga-PentixaFor in Hyperaldosteronism and Hypercortisolism
National Cancer Institute (NCI)
NCT06246357
Dose Response Relationship for Single Doses of Corticotropin Releasing Hormone (CRH) in Normal Volunteers and in Patients With Adrenal Insufficiency
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00001180
Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00001452
Study to Evaluate CORT125134 in Participants With Cushing's Syndrome
Corcept Therapeutics
NCT02804750
Novel Mediators of the Lipodystrophy and Metabolic Consequences of Cushing's Disease
Columbia University
NCT03817840
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Cushing's Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Cushing's Syndrome trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Cushing's Syndrome page
6 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Cushing's Syndrome trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) sponsors the most Cushing's Syndrome trials on record, review their full trial history before evaluating a specific study. See Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cushing's Syndrome condition card totals 6 registered trials; most-linked intervention Ovine Corticotropin-Releasing Hormone (oCRH); top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.