Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 2

Study to Evaluate CORT125134 in Participants With Cushing's Syndrome

NCT02804750 · View on ClinicalTrials.gov ↗

Study Summary

Cushing's syndrome is a relatively rare disorder caused by prolonged exposure to high levels of the glucocorticoid hormone cortisol. Cushing's syndrome may result from elevated endogenous or exogenous sources of cortisol. Endogenous Cushing's syndrome resulting from cortisol overproduction by the adrenal glands is the subject of this protocol. Patients with exogenous Cushing's syndrome, which develops as a side effect of chronic administration of high doses of glucocorticoids, were not eligible for enrollment in this study. The purpose of this study was to evaluate the safety and efficacy of CORT125134 for treatment of endogenous Cushing's syndrome. The multicenter study was conducted in the United States and in Europe.

Conditions Studied

Interventions

  • DRUG CORT125134

Study Locations (20)

Other

  • — Budapest
  • — Pécs
  • — Cuneo
  • — Messina
  • — Milan
  • — Naples
  • — Orbassano
  • — Roma

Florida

  • — Fort Lauderdale
  • — Miami

California

  • — Laguna Hills

Colorado

  • — Aurora

Indiana

  • — Indianapolis

Kentucky

  • — Covington

Minnesota

  • — Rochester

Missouri

  • — St Louis

Trial Details

FieldValue
Enrollment Target 35 participants
Start Date 2016-06
Est. Completion 2018-09
Phase Phase 2

Sponsor

Corcept Therapeutics

15 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02804750

The ClinicalTrials.gov registry entry for NCT02804750 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 35 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Corcept Therapeutics, which has 15 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Cushing's Syndrome appearing as the primary indexed condition, and to 1 intervention — of which CORT125134 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02804750 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Other, Florida, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02804750 about?

NCT02804750 is a clinical study titled "Study to Evaluate CORT125134 in Participants With Cushing's Syndrome". Cushing's syndrome is a relatively rare disorder caused by prolonged exposure to high levels of the glucocorticoid hormone cortisol. Cushing's syndrome may result from elevated endogenous or exogenous sources of cortisol. Endogenous Cushing's syndrome resulting from cortisol overproduction by the ad...

What is the current status of trial NCT02804750?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 35 participants. The study started on 2016-06. Estimated completion is 2018-09.

What conditions does trial NCT02804750 study?

This clinical trial studies the following conditions: Cushing's Syndrome. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02804750?

The interventions under investigation include: CORT125134 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02804750?

This trial is sponsored by Corcept Therapeutics, which has 15 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02804750 being conducted?

This trial has 20 study locations across California, Colorado, Florida, Indiana, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial