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ClinicalTrials.gov 18 recruiting now official registry

Congenital Diaphragmatic Hernia clinical trials

Every US clinical trial registered for Congenital Diaphragmatic Hernia — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

23 US clinical trials · 18 currently recruiting

The research picture

Congenital Diaphragmatic Hernia has 23 registered US clinical trials, 18 of them open to new participants right now — about 78% of the total.

18
recruiting participants now
78%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
2
top sponsor: Michael A Belfort

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 3,000 participants

Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science

Columbia University

NCT00950118

RECRUITING Phase 4 600 participants

De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia

The University of Texas Health Science Center, Houston

NCT05213676

RECRUITING NA 80 participants

Safety and Efficacy of FETO in CDH: A Phase III Trial

Holly L Hedrick, MD

NCT06884423

RECRUITING NA 80 participants

Fetal Endotracheal Occlusion (FETO) in the Resolution of Pulmonary Hypertension in Fetuses With Severe CDH

Michael A Belfort

NCT03980717

RECRUITING NA 80 participants

North American Fetal Therapy Network for Long-term Outcome Following Fetoscopic Endoluminal Tracheal Occlusion in Severe Left and Right Congenital Diaphragmatic Hernia

The University of Texas Health Science Center, Houston

NCT06739356

RECRUITING NA 80 participants

Prospective Registry for Long-term Outcomes Following FETO in Severe Left and Right CDH

Johns Hopkins University

NCT07166172

RECRUITING Phase 3 75 participants

Safety and Efficacy of FETO in CDH Phase III

Children's Hospital Medical Center, Cincinnati

NCT07187206

RECRUITING NA 50 participants

High Frequency Oscillatory Ventilation Versus High Frequency Jet Ventilation for Congenital Diaphragmatic Hernia

University of Utah

NCT04774848

RECRUITING Phase 2 40 participants

A Trial of Phosphodiesterase-5 Inhibitor in Neonatal Congenital Diaphragmatic Hernia (TOP-CDH)

University of Utah

NCT05201144

RECRUITING NA 40 participants

Feto-Endoscopic Tracheal Occlusion (FETO) for Severe Congenital Diaphragmatic Hernia

Children's Hospital Medical Center, Cincinnati

NCT02986087

RECRUITING NA 20 participants

Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Mauro H. Schenone

NCT05962346

RECRUITING NA 15 participants

Fetal Endoscopic Tracheal Occlusion (FETO) for Severe Congenital Diaphragmatic Hernia

Yair Blumenfeld

NCT05461222

RECRUITING NA 10 participants

Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Severe Left Congenital Diaphragmatic Hernia (CDH)

Hanmin Lee

NCT04583644

RECRUITING NA 10 participants

Fetal Endoscopic Tracheal Occlusion (FETO) Trial for Congenital Diaphragmatic Hernia (CDH)

Dr Erin Perrone

NCT04052828

RECRUITING NA 10 participants

Trial of FETO for Severe Congenital Diaphragmatic Hernia

Aimen F. Shaaban, MD

NCT05450653

RECRUITING NA 10 participants

Fetal Endoscopic Tracheal Occlusion for CDH (CDH)

University of California, Davis

NCT05421676

RECRUITING NA 10 participants

Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia (FETO)

Rodrigo Ruano

NCT03138863

RECRUITING NA 10 participants

Fetoscopic Endoluminal Tracheal Occlusion

University of Colorado, Denver

NCT03674372

ACTIVE NOT RECRUITING NA 22 participants

Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Congenital Diaphragm Hernia

Anthony Johnson

NCT02596802

ACTIVE NOT RECRUITING NA 21 participants

Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Severe Left Diaphragmatic Hernia (CDH)

Johns Hopkins University

NCT02710968

ACTIVE NOT RECRUITING NA 20 participants

Infant Survival and Long-term Outcome Following Fetoscopic Endoluminal Tracheal Occlusion in Severe Left and Right Congenital Diaphragmatic Hernia, A Phase III Trial

Inna Lobeck

NCT06179472

ACTIVE NOT RECRUITING NA 14 participants

Fetoscopic Endoluminal Tracheal Occlusion in Severe Left Congenital Diaphragmatic Hernia

Children's Hospital of Philadelphia

NCT02549820

COMPLETED NA 20 participants

Fetal Endotracheal Occlusion (FETO) in Severe and Extremely Severe Congenital Diaphragmatic Hernia

Michael A Belfort

NCT00881660

Phase Distribution

PhaseTrial count
Phase 2 1
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Congenital Diaphragmatic Hernia Trial Landscape

ClinicalTrials.gov lists 23 US studies indexed under Congenital Diaphragmatic Hernia, and 18 of those are currently open to recruitment — roughly 78% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Congenital Diaphragmatic Hernia shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Congenital Diaphragmatic Hernia is led by Michael A Belfort with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 23 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Congenital Diaphragmatic Hernia?

PlainTrial tracks 23 US clinical trials for Congenital Diaphragmatic Hernia, of which 18 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Congenital Diaphragmatic Hernia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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