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Congenital Diaphragmatic Hernia clinical trials
Every US clinical trial registered for Congenital Diaphragmatic Hernia — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
23 US clinical trials · 18 currently recruiting
The research picture
Congenital Diaphragmatic Hernia has 23 registered US clinical trials, 18 of them open to new participants right now — about 78% of the total.
- 18
- recruiting participants now
- 78%
- of trials open to enrollment
- 2
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Michael A Belfort
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science
Columbia University
NCT00950118
De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia
The University of Texas Health Science Center, Houston
NCT05213676
Safety and Efficacy of FETO in CDH: A Phase III Trial
Holly L Hedrick, MD
NCT06884423
Fetal Endotracheal Occlusion (FETO) in the Resolution of Pulmonary Hypertension in Fetuses With Severe CDH
Michael A Belfort
NCT03980717
North American Fetal Therapy Network for Long-term Outcome Following Fetoscopic Endoluminal Tracheal Occlusion in Severe Left and Right Congenital Diaphragmatic Hernia
The University of Texas Health Science Center, Houston
NCT06739356
Prospective Registry for Long-term Outcomes Following FETO in Severe Left and Right CDH
Johns Hopkins University
NCT07166172
Safety and Efficacy of FETO in CDH Phase III
Children's Hospital Medical Center, Cincinnati
NCT07187206
High Frequency Oscillatory Ventilation Versus High Frequency Jet Ventilation for Congenital Diaphragmatic Hernia
University of Utah
NCT04774848
A Trial of Phosphodiesterase-5 Inhibitor in Neonatal Congenital Diaphragmatic Hernia (TOP-CDH)
University of Utah
NCT05201144
Feto-Endoscopic Tracheal Occlusion (FETO) for Severe Congenital Diaphragmatic Hernia
Children's Hospital Medical Center, Cincinnati
NCT02986087
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
Mauro H. Schenone
NCT05962346
Fetal Endoscopic Tracheal Occlusion (FETO) for Severe Congenital Diaphragmatic Hernia
Yair Blumenfeld
NCT05461222
Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Severe Left Congenital Diaphragmatic Hernia (CDH)
Hanmin Lee
NCT04583644
Fetal Endoscopic Tracheal Occlusion (FETO) Trial for Congenital Diaphragmatic Hernia (CDH)
Dr Erin Perrone
NCT04052828
Trial of FETO for Severe Congenital Diaphragmatic Hernia
Aimen F. Shaaban, MD
NCT05450653
Fetal Endoscopic Tracheal Occlusion for CDH (CDH)
University of California, Davis
NCT05421676
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia (FETO)
Rodrigo Ruano
NCT03138863
Fetoscopic Endoluminal Tracheal Occlusion
University of Colorado, Denver
NCT03674372
Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Congenital Diaphragm Hernia
Anthony Johnson
NCT02596802
Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Severe Left Diaphragmatic Hernia (CDH)
Johns Hopkins University
NCT02710968
Infant Survival and Long-term Outcome Following Fetoscopic Endoluminal Tracheal Occlusion in Severe Left and Right Congenital Diaphragmatic Hernia, A Phase III Trial
Inna Lobeck
NCT06179472
Fetoscopic Endoluminal Tracheal Occlusion in Severe Left Congenital Diaphragmatic Hernia
Children's Hospital of Philadelphia
NCT02549820
Fetal Endotracheal Occlusion (FETO) in Severe and Extremely Severe Congenital Diaphragmatic Hernia
Michael A Belfort
NCT00881660
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Congenital Diaphragmatic Hernia Trial Landscape
ClinicalTrials.gov lists 23 US studies indexed under Congenital Diaphragmatic Hernia, and 18 of those are currently open to recruitment — roughly 78% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Congenital Diaphragmatic Hernia shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Congenital Diaphragmatic Hernia is led by Michael A Belfort with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 23 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Congenital Diaphragmatic Hernia?
PlainTrial tracks 23 US clinical trials for Congenital Diaphragmatic Hernia, of which 18 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Congenital Diaphragmatic Hernia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.