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ClinicalTrials.gov 10 recruiting now official registry

Colorectal Cancer Screening clinical trials

10 of 20 indexed Colorectal Cancer Screening trials are currently recruiting.

20 US clinical trials · 10 currently recruiting

Colorectal Cancer Screening is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 3 of these trials.

The research picture

Colorectal Cancer Screening has 20 registered US clinical trials, 10 of them open to new participants right now, about 50% of the total.

10
recruiting participants now
50%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
3
top sponsor: Massachusetts General Hospital
Phase 31Phase 41

Active & Recent Trials

20 total, page 1 of 1

RECRUITING NA 80,000 participants

Use of a Colorectal Cancer Screening Decision Support Tool in Primary Care

Massachusetts General Hospital

NCT06625983

RECRUITING NA 6,500 participants

Effectiveness of a Cloud-based Digital Health Navigation Program for Colorectal Cancer Screening

Digital Health Navigation Solutions

NCT06821009

RECRUITING 5,000 participants

Prospective Collection of Samples to Enable the Development of Natera Screening Assay for Early Cancer Detection

Natera

NCT06620627

RECRUITING 2,700 participants

Pilot Study for Colorectal Cancer and Advanced Adenoma Detection With the Mainz Biomed Colorectal Cancer Test

Mainz Biomed

NCT06864338

RECRUITING 1,000 participants

A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer

City of Hope Medical Center

NCT07224750

RECRUITING NA 350 participants

Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening

H. Lee Moffitt Cancer Center and Research Institute

NCT06745895

RECRUITING Phase 4 300 participants

Cleansing Options in Out-Patient Setting to Improve Tolerance (COOP SIT) Trial

Morehouse School of Medicine

NCT07215000

RECRUITING NA 184 participants

Impact of Protect Your Colon™ on CRC Screening

Cedars-Sinai Medical Center

NCT05929820

RECRUITING 45 participants

Positive Fit to Colonoscopy: Closing the Gap

Massachusetts General Hospital

NCT06763432

RECRUITING 40 participants

CRC Screening in Unscreened Individuals 45-54

Massachusetts General Hospital

NCT06757192

COMPLETED NA 7,465 participants

FLU-FIT Program at Kaiser Permanente Northern California

University of California, San Francisco

NCT01210235

COMPLETED NA 3,880 participants

Effect of Patient Portal Messaging Before Mailing Fecal Immunochemical Testing Kit on Colorectal Cancer Screening Rates

University of California, Los Angeles

NCT05115916

COMPLETED 2,404 participants

A Study of Cologuard™ in an Average Risk Population Assessing a Three Year Test Interval

Exact Sciences Corporation

NCT02419716

COMPLETED NA 802 participants

Collaborative Care to Reduce Depression and Increase Cancer Screening Among Low-Income Urban Women

Clinical Directors Network

NCT02273206

COMPLETED NA 728 participants

Information With or Without Numbers For Optimizing Reasoning About Medical Decisions

Indiana University

NCT02477553

COMPLETED NA 115 participants

Test Up Now Education Program

Florida A&M University

NCT04304001

COMPLETED Phase 3 100 participants

Study of Using Computerized Education to Increase Patients' Confidence in Their Ability to Be Screened for Colon Cancer

University of California, Davis

NCT00273585

COMPLETED 76 participants

Doctor-Patient Communication About Colorectal Cancer Screening

Memorial Sloan Kettering Cancer Center

NCT01534923

COMPLETED NA 48 participants

Multilevel Intervention Based on Colorectal Cancer (CRC) and Cervical Cancer Self-screening in Rural, Segregated Areas

Milton S. Hershey Medical Center

NCT04471194

COMPLETED NA 37 participants

Cancer Screening; Access; Awareness; Navigation

University of Illinois at Chicago

NCT04131946

Phase Distribution

PhaseTrial count
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Colorectal Cancer Screening Trial Landscape

20 indexed Colorectal Cancer Screening studies · 10 recruiting (50%).

Phase mix: 2 late (III/IV) vs 0 early (I/II).

Top sponsor: Massachusetts General Hospital (3 trials), 9 others listed. 20 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Colorectal Cancer Screening?

PlainTrial tracks 20 US clinical trials for Colorectal Cancer Screening, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Colorectal Cancer Screening?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.