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ClinicalTrials.gov 10 recruiting now official registry

Clonal Cytopenia of Undetermined Significance clinical trials

10 of 12 indexed Clonal Cytopenia of Undetermined Significance trials are currently recruiting.

12 US clinical trials · 10 currently recruiting

Clonal Cytopenia of Undetermined Significance is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Washington University School of Medicine, running 3 of these trials.

The research picture

Clonal Cytopenia of Undetermined Significance has 12 registered US clinical trials, 10 of them open to new participants right now, about 83% of the total.

10
recruiting participants now
83%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
3
top sponsor: Washington University School of Medicine
Phase 11Phase 27

Active & Recent Trials

12 total, page 1 of 1

RECRUITING NA 2,000 participants

Pre-myeloid Cancer and Bone Marrow Failure Clinic Study

Mayo Clinic

NCT02958462

RECRUITING 2,000 participants

Clonal Hematopoiesis and Therapy-Emergent Myeloid Neoplasms in Patients With Cancers, CHANCES Study

University of Washington

NCT06295965

RECRUITING 306 participants

CHIP/CCUS Natural History Protocol

National Heart, Lung, and Blood Institute (NHLBI)

NCT04102423

RECRUITING Phase 2 110 participants

Canakinumab for the Prevention of Progression to Cancer in Patients With Clonal Cytopenias of Unknown Significance, IMPACT Study

Uma Borate

NCT05641831

RECRUITING Early Phase 1 108 participants

Early Intervention in High Risk CCUS

Lachelle D. Weeks, MD, PhD

NCT06802146

RECRUITING Phase 2 80 participants

Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

Mayo Clinic

NCT03418038

RECRUITING Phase 2 30 participants

Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms

University of Southern California

NCT06063486

RECRUITING Phase 2 16 participants

Statins in Patients With Clonal Cytopenia of Undetermined Significance (CCUS) and Myelodysplastic Syndromes (MDS)

Washington University School of Medicine

NCT05483010

RECRUITING Phase 2 15 participants

A Phase 2 Study Evaluating Olutasidenib in Patients With IDH1-mutated Clonal Cytopenia of Undetermined Significance and Lower-risk Myelodysplastic/Syndromes/Chronic Myelomonocytic Leukemia.

M.D. Anderson Cancer Center

NCT06566742

RECRUITING Phase 2 15 participants

Enasidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH2A Decentralized Trial

Washington University School of Medicine

NCT06240754

ACTIVE NOT RECRUITING 100 participants

Acquired Pyruvate Kinase Deficiency In Clonal Myeloid Neoplasms

Massachusetts General Hospital

NCT04902833

ACTIVE NOT RECRUITING Phase 2 20 participants

Ivosidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH1

Washington University School of Medicine

NCT05030441

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 7

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Clonal Cytopenia of Undetermined Significance Trial Landscape

12 indexed Clonal Cytopenia of Undetermined Significance studies · 10 recruiting (83%).

Phase mix: 0 late (III/IV) vs 8 early (I/II).

Top sponsor: Washington University School of Medicine (3 trials), 8 others listed. 12 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Clonal Cytopenia of Undetermined Significance?

PlainTrial tracks 12 US clinical trials for Clonal Cytopenia of Undetermined Significance, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Clonal Cytopenia of Undetermined Significance?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.