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NCT06240754 · ClinicalTrials.gov registry record · Phase 2

Enasidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH2A Decentralized Trial

A Phase 2 study of Clonal Cytopenia of Undetermined Significance and CCUS Clonal Cytopenia of Undetermined Significance, sponsored by Washington University School of Medicine.

Recruiting
Registry status
Phase 2
Development phase
15
Enrollment target
1
Study location

NCT06240754 is a Phase 2 study of Clonal Cytopenia of Undetermined Significance and CCUS Clonal Cytopenia of Undetermined Significance that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 15 participants, below the 435-participant average among 11 other Clonal Cytopenia of Undetermined Significance trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06240754, a Phase 2 study of Clonal Cytopenia of Undetermined Significance and CCUS Clonal Cytopenia of Undetermined Significance, is actively recruiting participants, sponsored by Washington University School of Medicine.

RECRUITING
Registry status
Phase 2
Development phase
15 participants
Enrollment target
1
Study location

Study Summary

Study researchers think that a drug called enasidenib may help people with clonal cytopenia of undetermined significance (CCUS) because the drug blocks the mutated IDH2 protein, which may improve blood cell counts. The purpose of this study is to find out whether enasidenib is a safe and effective treatment for CCUS.

Interventions

  • DRUG Enasidenib

Study Locations (1)

Missouri

  • Washington University School of Medicine - St Louis

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2024-10-10
Est. Completion 2029-02-28
Phase Phase 2

What the Registry Record Tells You About NCT06240754

The ClinicalTrials.gov registry entry for NCT06240754 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 435-participant average among 11 other Clonal Cytopenia of Undetermined Significance trials with a reported enrollment target (97% lower). The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Clonal Cytopenia of Undetermined Significance appearing as the primary indexed condition, and to 1 intervention - of which Enasidenib is the first listed.

NCT06240754 reports 1 study location spanning 1 distinct geographic area - top geographies include Missouri.

Frequently Asked Questions

What is clinical trial NCT06240754 about?

NCT06240754 is a clinical study titled "Enasidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH2A Decentralized Trial". Study researchers think that a drug called enasidenib may help people with clonal cytopenia of undetermined significance (CCUS) because the drug blocks the mutated IDH2 protein, which may improve blood cell counts. The purpose of this study is to find out whether enasidenib is a safe and effective t...

What is the current status of trial NCT06240754?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2024-10-10. Estimated completion is 2029-02-28.

What conditions does trial NCT06240754 study?

This clinical trial studies the following conditions: Clonal Cytopenia of Undetermined Significance, CCUS Clonal Cytopenia of Undetermined Significance.

What interventions are being tested in trial NCT06240754?

The interventions under investigation include: Enasidenib (DRUG).

Who is sponsoring clinical trial NCT06240754?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06240754 being conducted?

This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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