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Chronic Low Back Pain: early-phase trial registry
30 of 72 indexed Chronic Low Back Pain trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #191 of 28,707 conditions by registered trial count.
72 US clinical trials · 30 currently recruiting · #191 of 28,707 conditions by registered trial count
Chronic Low Back Pain: 72 US clinical trials tracked, 30 recruiting.
Chronic Low Back Pain is the subject of 72 registered US clinical trials on ClinicalTrials.gov, 30 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 6 of these trials.
Enrollment posture brief
Registry condition chronic-low-back-pain
OPEN 30 | RECR 42% | LATE 5 | EARLY 15 | RANK #191 | SPON 6
Volume-matched condition peers
Nearest open-share peer: Acute Myeloid Leukemia in Remission (42% recruiting · 12 trials)
Chronic Low Back Pain lists 30 open slots (42% of 72 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Chronic Low Back Pain on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Chronic Low Back Pain is recruiting above its size-band peers.
30 of 72 indexed trials (41.7%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Chronic Low Back Pain trials is spread across many organizations.
VA Office of Research and Development accounts for 6 of 72 trials (8.3%). 49 distinct sponsors appear on at least one study for this condition label.
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Typical Chronic Low Back Pain enrolment sits around 70 participants.
Median target enrolment is 70 among the 72 trials that report a genuine target (sentinel values excluded). 39 of those (54.2%) plan for fewer than 100 participants.
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Chronic Low Back Pain research is mostly interventional.
62 interventional and 10 observational studies make up this index (86.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
72 total, page 2 of 2
Ultrasound Imaging for Myofascial Pain
University of Pittsburgh
NCT05928884
Mindfulness and Chronic Low Back Pain
University of California, San Diego
NCT03354585
MIS MiLIF Versus Open
Zimmer Biomet
NCT00792129
Chronic Low Back Pain Research Project
US Department of Veterans Affairs
NCT00108550
Pilot Study of the Efficacy and Safety of Lidoderm Patch in the Treatment of Low Back Pain
Endo Pharmaceuticals
NCT00904475
Brain Mechanisms of Acupuncture Treatment in Chronic Low Back Pain
Brigham and Women's Hospital
NCT01595451
Telehealth Mindfulness After Spine Surgery
Vanderbilt University Medical Center
NCT05698914
Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)
VA Office of Research and Development
NCT02697435
Battlefield Acupuncture for Low Back Pain
The Geneva Foundation
NCT03491124
Correlation of Trust and Outcomes Following Physical Therapy for Chronic Low Back Pain
University of South Dakota
NCT03443401
Study of PIPE-791 for Subjects With Chronic Osteoarthritis Pain or Chronic Low Back Pain
Contineum Therapeutics
NCT06810245
Meditation and Exercise to Treat Chronic Back Pain
Duquesne University
NCT03324659
Effects of Spinal Stabilization Exercises on Dynamic Balance and Functional Performance in Adults With Low Back Pain
Texas Woman's University
NCT03597191
Methylglyoxal Evaluation in Humans
University of Kansas Medical Center
NCT05350553
Determining the Prognostic Value of Continuous Intrathecal Infusion
University Hospitals Cleveland Medical Center
NCT03523000
Self-Management of Chronic Low Back Pain: Targeting Patient Activation
Johns Hopkins University
NCT06236529
Yoga and Mantram for Chronic Pain and PTSD
VA Office of Research and Development
NCT03816007
Virtual Reality Guided Acupuncture Imagery Treatment for Chronic Low Back Pain
Massachusetts General Hospital
NCT06814470
Research Study on Patient Education for People With Chronic Low Back Pain
University of Pittsburgh
NCT06492642
MEPS-Pain: Personalized Pain Self-management Planning by and for Veterans Pilot Study
VA Office of Research and Development
NCT04075487
Vertical Climbing (CLMBR) Exercise for Chronic Low Back Pain
Icahn School of Medicine at Mount Sinai
NCT05483608
Low-Dose Naltrexone and Acetaminophen Combination in the Treatment of Chronic Low Back Pain (ANODYNE-4)
Allodynic Therapeutics
NCT03201393
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 9 |
| Phase 3 | 1 |
| Phase 4 | 4 |
Top Sponsors
Named interventions
Most-linked intervention names on Chronic Low Back Pain records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Chronic Low Back Pain trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Chronic Low Back Pain page
72 registered trials, 30 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 30 Chronic Low Back Pain trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Chronic Low Back Pain trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Chronic Low Back Pain condition card totals 72 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.