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Chordoma clinical trials
7 of 16 indexed Chordoma trials are currently recruiting.
16 US clinical trials · 7 currently recruiting
Chordoma is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 2 of these trials.
The research picture
Chordoma has 16 registered US clinical trials, 7 of them open to new participants right now, about 44% of the total.
- 7
- recruiting participants now
- 44%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 2
- top sponsor: M.D. Anderson Cancer Center
Active & Recent Trials
16 total, page 1 of 1
Long-Term Longitudinal QoL in Patients Undergoing EEA
Ohio State University
NCT04087902
Children and Adults With Chordoma
National Cancer Institute (NCI)
NCT03910465
Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the Bone
Mayo Clinic
NCT05033288
Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def Tumors
Susan Chi, MD
NCT05407441
A Study of ERAS-601 in People With Chordoma
Memorial Sloan Kettering Cancer Center
NCT06957327
Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors
University of Florida
NCT06625190
Pembrolizumab and Pemetrexed for Progressive Chordoma
Saint John's Cancer Institute
NCT06794645
Cetuximab for the Treatment of Advanced Unresectable or Metastatic Chordoma
M.D. Anderson Cancer Center
NCT05041127
Nivolumab With or Without Stereotactic Radiosurgery in Treating Patients With Recurrent, Advanced, or Metastatic Chordoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT02989636
Proton Beam Therapy for Chordoma Patients
M.D. Anderson Cancer Center
NCT00496119
Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma
Children's Oncology Group
NCT00919269
Chordoma Family Study
National Cancer Institute (NCI)
NCT00410670
Stereotactic Body Radiotherapy for Spine Tumors
Mercy Research
NCT01347307
TAEK-VAC-HerBy Vaccine for Brachyury and HER2 Expressing Cancer
Bavarian Nordic
NCT04246671
Nilotinib With Radiation for High Risk Chordoma
Massachusetts General Hospital
NCT01407198
Hypoxia-positron Emission Tomography (PET) and Intensity Modulated Proton Therapy (IMPT) Dose Painting in Patients With Chordomas
Massachusetts General Hospital
NCT00713037
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Chordoma Trial Landscape
16 indexed Chordoma studies · 7 recruiting (44%).
Phase mix: 0 late (III/IV) vs 9 early (I/II).
Top sponsor: M.D. Anderson Cancer Center (2 trials), 9 others listed. 16 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Chordoma?
PlainTrial tracks 16 US clinical trials for Chordoma, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Chordoma?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.