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2026 data Public-data reference. official source

Chordoma

Open-data reference.

16 US clinical trials · 7 currently recruiting

Active & Recent Trials

RECRUITING 400 participants

Long-Term Longitudinal QoL in Patients Undergoing EEA

Ohio State University

NCT04087902

RECRUITING 300 participants

Children and Adults With Chordoma

National Cancer Institute (NCI)

NCT03910465

RECRUITING 72 participants

Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the Bone

Mayo Clinic

NCT05033288

RECRUITING Phase 1 49 participants

Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def Tumors

Susan Chi, MD

NCT05407441

RECRUITING Phase 1 46 participants

A Study of ERAS-601 in People With Chordoma

Memorial Sloan Kettering Cancer Center

NCT06957327

RECRUITING Phase 1 27 participants

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

University of Florida

NCT06625190

RECRUITING Phase 2 21 participants

Pembrolizumab and Pemetrexed for Progressive Chordoma

Saint John's Cancer Institute

NCT06794645

ACTIVE NOT RECRUITING Phase 2 29 participants

Cetuximab for the Treatment of Advanced Unresectable or Metastatic Chordoma

M.D. Anderson Cancer Center

NCT05041127

ACTIVE NOT RECRUITING Phase 1 21 participants

Nivolumab With or Without Stereotactic Radiosurgery in Treating Patients With Recurrent, Advanced, or Metastatic Chordoma

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT02989636

ACTIVE NOT RECRUITING Phase 2 19 participants

Proton Beam Therapy for Chordoma Patients

M.D. Anderson Cancer Center

NCT00496119

COMPLETED 150 participants

Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma

Children's Oncology Group

NCT00919269

COMPLETED 55 participants

Chordoma Family Study

National Cancer Institute (NCI)

NCT00410670

COMPLETED NA 38 participants

Stereotactic Body Radiotherapy for Spine Tumors

Mercy Research

NCT01347307

COMPLETED Phase 1 37 participants

TAEK-VAC-HerBy Vaccine for Brachyury and HER2 Expressing Cancer

Bavarian Nordic

NCT04246671

COMPLETED Phase 1 23 participants

Nilotinib With Radiation for High Risk Chordoma

Massachusetts General Hospital

NCT01407198

COMPLETED NA 20 participants

Hypoxia-positron Emission Tomography (PET) and Intensity Modulated Proton Therapy (IMPT) Dose Painting in Patients With Chordomas

Massachusetts General Hospital

NCT00713037

Phase Distribution

PhaseTrial count
Early Phase 1 6
Phase 2 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Chordoma Trial Landscape

ClinicalTrials.gov lists 16 US studies indexed under Chordoma, and 7 of those are currently open to recruitment — roughly 44% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Chordoma shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Chordoma is led by M.D. Anderson Cancer Center with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 16 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Chordoma?

PlainTrial tracks 16 US clinical trials for Chordoma, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Chordoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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