Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Central Nervous System Diseases: early-phase trial registry
7 of 16 indexed Central Nervous System Diseases trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,060 of 28,707 conditions by registered trial count.
16 US clinical trials · 7 currently recruiting · #1,060 of 28,707 conditions by registered trial count
Central Nervous System Diseases: 16 US clinical trials tracked, 7 recruiting.
Central Nervous System Diseases is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Kessler Foundation, running 2 of these trials.
Enrollment posture brief
Registry condition central-nervous-system-diseases
OPEN 7 | RECR 44% | LATE 1 | EARLY 6 | RANK #1060 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Acute Respiratory Distress Syndrome (44% recruiting · 32 trials)
Central Nervous System Diseases lists 7 open slots (44% of 16 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Central Nervous System Diseases on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Central Nervous System Diseases is recruiting below its size-band peers.
7 of 16 indexed trials (43.8%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
Sponsorship of Central Nervous System Diseases trials is spread across many organizations.
Kessler Foundation accounts for 2 of 16 trials (12.5%). 14 distinct sponsors appear on at least one study for this condition label.
-
Most Central Nervous System Diseases trials plan to enrol fewer than 100 people.
Median target enrolment is 80 among the 16 trials that report a genuine target (sentinel values excluded). 11 of those (68.8%) plan for fewer than 100 participants.
-
Central Nervous System Diseases research is mostly interventional.
15 interventional and 1 observational studies make up this index (93.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
16 total, page 1 of 1
Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII
Black Diamond Therapeutics
NCT07326566
Brain Connections for Arm Movement After Stroke
VA Office of Research and Development
NCT04286516
Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
Stemline Therapeutics
NCT05386108
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
North Florida Foundation for Research and Education
NCT04460872
Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)
Kessler Foundation
NCT05731986
Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke
Jorge Gonzalez-Martinez
NCT06303869
The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)
Kessler Foundation
NCT05725499
Mobile Parkinson Observatory for Worldwide, Evidence-based Research (mPower)
Sage Bionetworks
NCT02696603
A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease (TRAILBLAZER-ALZ 6)
Eli Lilly and Company
NCT05738486
pRESET for Occlusive Stroke Treatment
phenox
NCT03994822
Safety and Cognitive Function Study of EVP-6124 in Patients With Schizophrenia
FORUM Pharmaceuticals
NCT00968851
A Follow-On Study of Donanemab (LY3002813) With Video Assessments in Participants With Alzheimer's Disease (TRAILBLAZER-EXT)
Eli Lilly and Company
NCT04640077
A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases
AbbVie (prior sponsor, Abbott)
NCT00649207
Harmony at Home: A Pilot Telehealth Program for Rural ADRD Caregivers
Elizabeth K Rhodus
NCT05202223
Central Nervous System Disease in HIV-infected Children on HAART
National Cancer Institute (NCI)
NCT00110331
Stimulation With Wire Leads to Restore Cough
MetroHealth Medical Center
NCT01659541
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 4 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Central Nervous System Diseases records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Central Nervous System Diseases trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Central Nervous System Diseases page
16 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 7 Central Nervous System Diseases trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Kessler Foundation sponsors the most Central Nervous System Diseases trials on record, review their full trial history before evaluating a specific study. See Kessler Foundation's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Central Nervous System Diseases condition card totals 16 registered trials; most-linked intervention Placebo; top US site state New Jersey. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.