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ClinicalTrials.gov 7 recruiting now official registry

Breast Ductal Carcinoma In Situ clinical trials

Every US clinical trial registered for Breast Ductal Carcinoma In Situ — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

13 US clinical trials · 7 currently recruiting

The research picture

Breast Ductal Carcinoma In Situ has 13 registered US clinical trials, 7 of them open to new participants right now — about 54% of the total.

7
recruiting participants now
54%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
5
top sponsor: National Cancer Institute (NCI)

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING NA 27,500 participants

Identifying and Caring for Individuals With Inherited Cancer Syndrome

OHSU Knight Cancer Institute

NCT04494945

RECRUITING 600 participants

Impact of COVID-19 Pandemic on Out-of-Pocket Costs, Lost Wages, and Unemployment in Patients With Breast Cancer Undergoing Breast Surgery

M.D. Anderson Cancer Center

NCT04169542

RECRUITING Phase 2 200 participants

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

National Cancer Institute (NCI)

NCT06184750

RECRUITING Phase 2 80 participants

Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

National Cancer Institute (NCI)

NCT05941520

RECRUITING Phase 2 66 participants

Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction

National Cancer Institute (NCI)

NCT06195306

RECRUITING Phase 1 43 participants

A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ

Mayo Clinic

NCT04144023

RECRUITING Phase 2 36 participants

High Cannabidiol Plant Extract (BRC-001) to Improve Aromatase Inhibitor-Induced Arthralgia in Women With Breast Cancer

City of Hope Medical Center

NCT06538389

ACTIVE NOT RECRUITING Phase 3 5,018 participants

Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer

National Cancer Institute (NCI)

NCT01272037

ACTIVE NOT RECRUITING Phase 1 208 participants

Comparing Supplemental Topical Agents for the Treatment of Acute Radiation Dermatitis in Patients With Breast Cancer

City of Hope Medical Center

NCT05340673

ACTIVE NOT RECRUITING Phase 2 120 participants

Metformin and Nightly Fasting in Women With Early Breast Cancer

M.D. Anderson Cancer Center

NCT05023967

ACTIVE NOT RECRUITING Phase 2 113 participants

Volumetric Specimen Imager Device for the Intraoperative Imaging of Patients With Breast Carcinoma and Breast Ductal Carcinoma In Situ, The VIVID Study

Northwestern University

NCT05545150

ACTIVE NOT RECRUITING Phase 1 32 participants

Phase I Trial of Endoxifen Gel Versus Placebo in Women Undergoing Breast Surgery

National Cancer Institute (NCI)

NCT03317405

COMPLETED NA 50 participants

EMBr Wave for the Reduction of Hot Flashes in Women With a History of Breast Cancer

Ohio State University Comprehensive Cancer Center

NCT05086705

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 6
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Breast Ductal Carcinoma In Situ Trial Landscape

ClinicalTrials.gov lists 13 US studies indexed under Breast Ductal Carcinoma In Situ, and 7 of those are currently open to recruitment — roughly 54% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Breast Ductal Carcinoma In Situ shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Breast Ductal Carcinoma In Situ is led by National Cancer Institute (NCI) with 5 indexed trials, alongside 6 other organizations in the top contributor list. The list on this page surfaces up to 13 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Breast Ductal Carcinoma In Situ?

PlainTrial tracks 13 US clinical trials for Breast Ductal Carcinoma In Situ, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Breast Ductal Carcinoma In Situ?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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