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ClinicalTrials.gov 10 recruiting now early-phase tilt small index

Breast Ductal Carcinoma In Situ: early-phase trial registry

10 of 16 indexed Breast Ductal Carcinoma In Situ trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,060 of 28,707 conditions by registered trial count.

16 US clinical trials · 10 currently recruiting · #1,060 of 28,707 conditions by registered trial count

Breast Ductal Carcinoma In Situ: 16 US clinical trials tracked, 10 recruiting.

Breast Ductal Carcinoma In Situ is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 5 of these trials.

Enrollment posture brief

Registry condition breast-ductal-carcinoma-in-situ

OPEN 10 | RECR 63% | LATE 1 | EARLY 9 | RANK #1060 | SPON 5

Nearest open-share peer: Advanced Gastroesophageal Junction Adenocarcinoma (63% recruiting · 8 trials)

Breast Ductal Carcinoma (this)Breast Ductal Carcinoma (th…63%Adolescent62.5%Alcohol Intoxication56.3%AL Amyloidosis43.8%Allergy18.8%
Open-enrollment share among volume-matched conditions near Breast Ductal Carcinoma In Situ

Breast Ductal Carcinoma In Situ lists 10 open slots (63% of 16 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Breast Ductal Carcinoma In Situ on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Breast Ductal Carcinoma In Situ is recruiting above its size-band peers.

    10 of 16 indexed trials (62.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Breast Ductal Carcinoma In Situ research.

    National Cancer Institute (NCI) accounts for 5 of 16 trials (31.3%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Typical Breast Ductal Carcinoma In Situ enrolment sits around 113 participants.

    Median target enrolment is 113 among the 16 trials that report a genuine target (sentinel values excluded). 8 of those (50%) plan for fewer than 100 participants.

  4. Breast Ductal Carcinoma In Situ research is mostly interventional.

    15 interventional and 1 observational studies make up this index (93.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 26Phase 31

Open and recent trials

16 total, page 1 of 1

RECRUITING NA 27,500 participants

Identifying and Caring for Individuals With Inherited Cancer Syndrome

OHSU Knight Cancer Institute

NCT04494945

RECRUITING 600 participants

Impact of COVID-19 Pandemic on Out-of-Pocket Costs, Lost Wages, and Unemployment in Patients With Breast Cancer Undergoing Breast Surgery

M.D. Anderson Cancer Center

NCT04169542

RECRUITING Phase 2 200 participants

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

National Cancer Institute (NCI)

NCT06184750

RECRUITING NA 126 participants

A Patient Navigation Program for Addressing Disparities in Breast Cancer Care

Roswell Park Cancer Institute

NCT06350500

RECRUITING Phase 2 80 participants

Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

National Cancer Institute (NCI)

NCT05941520

RECRUITING NA 80 participants

Pre-operative SABR With and Without Caloric Restriction for Early Stage Breast Cancer

Thomas Jefferson University

NCT04959474

RECRUITING Phase 2 66 participants

Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction

National Cancer Institute (NCI)

NCT06195306

RECRUITING NA 55 participants

Neoadjuvant Breast Cancer Time Restricted Eating

Thomas Jefferson University

NCT05327608

RECRUITING Phase 1 43 participants

A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ

Mayo Clinic

NCT04144023

RECRUITING Phase 2 36 participants

High Cannabidiol Plant Extract (BRC-001) to Improve Aromatase Inhibitor-Induced Arthralgia in Women With Breast Cancer

City of Hope Medical Center

NCT06538389

ACTIVE NOT RECRUITING Phase 3 5,018 participants

Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer

National Cancer Institute (NCI)

NCT01272037

ACTIVE NOT RECRUITING Phase 1 208 participants

Comparing Supplemental Topical Agents for the Treatment of Acute Radiation Dermatitis in Patients With Breast Cancer

City of Hope Medical Center

NCT05340673

ACTIVE NOT RECRUITING Phase 2 120 participants

Metformin and Nightly Fasting in Women With Early Breast Cancer

M.D. Anderson Cancer Center

NCT05023967

ACTIVE NOT RECRUITING Phase 2 113 participants

Volumetric Specimen Imager Device for the Intraoperative Imaging of Patients With Breast Carcinoma and Breast Ductal Carcinoma In Situ, The VIVID Study

Northwestern University

NCT05545150

ACTIVE NOT RECRUITING Phase 1 32 participants

Phase I Trial of Endoxifen Gel Versus Placebo in Women Undergoing Breast Surgery

National Cancer Institute (NCI)

NCT03317405

COMPLETED NA 50 participants

EMBr Wave for the Reduction of Hot Flashes in Women With a History of Breast Cancer

Ohio State University Comprehensive Cancer Center

NCT05086705

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 6
Phase 3 1

Named interventions

Most-linked intervention names on Breast Ductal Carcinoma In Situ records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Questionnaire Administration Other
8 trials
Biospecimen Collection Procedure
7 trials
Mammography Procedure
3 trials
Random Periareolar Fine-Needle Aspiration Procedure
2 trials
Quality-of-Life Assessment Other
2 trials
EMBr Wave Device
1 trials
Petrolatum-Mineral Oil-Lanolin-Ceresin Ointment Other
1 trials
Agent Affecting Integumentary System Drug
1 trials

US sites by state

Facility locations filed on Breast Ductal Carcinoma In Situ trials. A trial with sites in several states counts in each.

Ohio 5 trials
California 5 trials
Illinois 4 trials
Texas 3 trials
Kansas 3 trials
Pennsylvania 2 trials
New York 2 trials
Missouri 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Breast Ductal Carcinoma In Situ page

16 registered trials, 10 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Breast Ductal Carcinoma In Situ condition card totals 16 registered trials; most-linked intervention Questionnaire Administration; top US site state Ohio. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.