Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Breast Cancer Stage III

Open-data reference.

21 US clinical trials · 10 currently recruiting

Active & Recent Trials

RECRUITING NA 800 participants

Optimizing Surgical Decisions in Young Adults With Breast Cancer

Weill Medical College of Cornell University

NCT06275126

RECRUITING NA 700 participants

A Study of Language Interpretation Solutions for People With Breast Cancer

Memorial Sloan Kettering Cancer Center

NCT06721065

RECRUITING Phase 2 185 participants

Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer

Baylor Breast Care Center

NCT05020860

RECRUITING NA 100 participants

Effect of Meal Timing During Cancer Treatment in Patients in Alaska: A Randomized Clinical Trial

Fred Hutchinson Cancer Center

NCT06802172

RECRUITING NA 100 participants

Evaluation of Radiobiological Effects in Skin Toxicities for Breast Cancer Patients With Pencil Beam Scanning Proton Therapy

Covenant Health Cancer Center

NCT06006806

RECRUITING Phase 2 90 participants

Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer

UNC Lineberger Comprehensive Cancer Center

NCT06727773

RECRUITING Phase 2 90 participants

Predicting Response to Neoadjuvant Endocrine Therapy (Neo-PREDICT)

George Washington University

NCT06806930

RECRUITING Phase 2 86 participants

Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy

University of California, Davis

NCT06268665

RECRUITING Phase 2 45 participants

Adjuvant Chemoradiation and Biomarkers of Response in High-risk Breast Cancer

University of Virginia

NCT05288777

RECRUITING 10 participants

Evaluating and Monitoring Immune and Clinical Responses in Early-Stage Triple Negative Breast Cancer Undergoing Neoadjuvant Chemo-immunotherapy With Pembrolizumab

Emory University

NCT05877859

ACTIVE NOT RECRUITING NA 627 participants

Increasing Patients' Engagement in Breast Cancer Surgery Decision-Making

Alliance for Clinical Trials in Oncology

NCT03766009

ACTIVE NOT RECRUITING Phase 3 534 participants

Axillary Reverse Mapping in Preventing Lymphedema in Patients With Breast Cancer Undergoing Axillary Lymph Node Dissection

Alliance for Clinical Trials in Oncology

NCT03927027

ACTIVE NOT RECRUITING Phase 1 120 participants

Evaluate BL-M17D1 in Patients w/HER2-Expressing/Mutant Advanced or Metastatic Solid Tumors

SystImmune

NCT06714617

ACTIVE NOT RECRUITING Phase 2 119 participants

Vaccine to Prevent Recurrence in Patients With HER-2 Positive Breast Cancer

H. Lee Moffitt Cancer Center and Research Institute

NCT03384914

ACTIVE NOT RECRUITING NA 102 participants

Taking AIM at Breast Cancer

Dana-Farber Cancer Institute

NCT04720209

ACTIVE NOT RECRUITING 100 participants

The Differential Impact of Proton Beam Irradiation Versus Conventional Radiation on Organs-at-risk in Stage II-III Breast Cancer Patients

Massachusetts General Hospital

NCT03270072

ACTIVE NOT RECRUITING NA 60 participants

Ultrahypofractionation and Normal Tissue Toxicity

Massachusetts General Hospital

NCT05912231

ACTIVE NOT RECRUITING NA 34 participants

Safety of Lower Scalp Cooling Temperature to Prevent Hair Loss From Chemotherapy in Breast Cancer Patients

Memorial Sloan Kettering Cancer Center

NCT04180579

ACTIVE NOT RECRUITING NA 30 participants

CARE (Chemotherapy Alopecia REduction)

George Washington University

NCT07201389

ACTIVE NOT RECRUITING 23 participants

Study of Cardiopulmonary Exercise Testing in Women Who Have HER2-Positive Breast Cancer With Mild Cardiotoxicity

Memorial Sloan Kettering Cancer Center

NCT05036252

ACTIVE NOT RECRUITING NA 23 participants

Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors

Case Comprehensive Cancer Center

NCT06336538

Phase Distribution

PhaseTrial count
Early Phase 1 1
Phase 2 6
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Breast Cancer Stage III Trial Landscape

ClinicalTrials.gov lists 21 US studies indexed under Breast Cancer Stage III, and 10 of those are currently open to recruitment — roughly 48% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Breast Cancer Stage III shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 7 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Breast Cancer Stage III is led by Memorial Sloan Kettering Cancer Center with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 21 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Breast Cancer Stage III?

PlainTrial tracks 21 US clinical trials for Breast Cancer Stage III, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Breast Cancer Stage III?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →