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ClinicalTrials.gov 10 recruiting now early-phase tilt

Breast Cancer Stage III: early-phase trial registry

10 of 22 indexed Breast Cancer Stage III trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #756 of 28,707 conditions by registered trial count.

22 US clinical trials · 10 currently recruiting · #756 of 28,707 conditions by registered trial count

Breast Cancer Stage III: 22 US clinical trials tracked, 10 recruiting.

Breast Cancer Stage III is the subject of 22 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 3 of these trials.

Enrollment posture brief

Registry condition breast-cancer-stage-iii

OPEN 10 | RECR 45% | LATE 1 | EARLY 8 | RANK #756 | SPON 3

Nearest open-share peer: Acute Stroke (45% recruiting · 11 trials)

Advanced Melanoma63.6%Breast Cancer Stage III (thi…45%Acute Myeloid Leukemia Arisi18.2%Adenocarcinoma of the Prosta0%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Breast Cancer Stage III

Breast Cancer Stage III lists 10 open slots (45% of 22 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Breast Cancer Stage III on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Breast Cancer Stage III is recruiting above its size-band peers.

    10 of 22 indexed trials (45.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Breast Cancer Stage III trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 3 of 22 trials (13.6%). 17 distinct sponsors appear on at least one study for this condition label.

  3. Typical Breast Cancer Stage III enrolment sits around 100 participants.

    Median target enrolment is 100 among the 22 trials that report a genuine target (sentinel values excluded). 11 of those (50%) plan for fewer than 100 participants.

  4. Breast Cancer Stage III research is mostly interventional.

    19 interventional and 3 observational studies make up this index (86.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 27Phase 31

Open and recent trials

22 total, page 1 of 1

RECRUITING NA 800 participants

Optimizing Surgical Decisions in Young Adults With Breast Cancer

Weill Medical College of Cornell University

NCT06275126

RECRUITING NA 700 participants

A Study of Language Interpretation Solutions for People With Breast Cancer

Memorial Sloan Kettering Cancer Center

NCT06721065

RECRUITING Phase 2 185 participants

Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer

Baylor Breast Care Center

NCT05020860

RECRUITING NA 100 participants

Effect of Meal Timing During Cancer Treatment in Patients in Alaska: A Randomized Clinical Trial

Fred Hutchinson Cancer Center

NCT06802172

RECRUITING NA 100 participants

Evaluation of Radiobiological Effects in Skin Toxicities for Breast Cancer Patients With Pencil Beam Scanning Proton Therapy

Covenant Health Cancer Center

NCT06006806

RECRUITING Phase 2 90 participants

Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer

UNC Lineberger Comprehensive Cancer Center

NCT06727773

RECRUITING Phase 2 90 participants

Predicting Response to Neoadjuvant Endocrine Therapy (Neo-PREDICT)

George Washington University

NCT06806930

RECRUITING Phase 2 86 participants

Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy

University of California, Davis

NCT06268665

RECRUITING Phase 2 45 participants

Adjuvant Chemoradiation and Biomarkers of Response in High-risk Breast Cancer

University of Virginia

NCT05288777

RECRUITING 10 participants

Evaluating and Monitoring Immune and Clinical Responses in Early-Stage Triple Negative Breast Cancer Undergoing Neoadjuvant Chemo-immunotherapy With Pembrolizumab

Emory University

NCT05877859

ACTIVE NOT RECRUITING NA 627 participants

Increasing Patients' Engagement in Breast Cancer Surgery Decision-Making

Alliance for Clinical Trials in Oncology

NCT03766009

ACTIVE NOT RECRUITING Phase 3 534 participants

Axillary Reverse Mapping in Preventing Lymphedema in Patients With Breast Cancer Undergoing Axillary Lymph Node Dissection

Alliance for Clinical Trials in Oncology

NCT03927027

ACTIVE NOT RECRUITING Phase 1 120 participants

Evaluate BL-M17D1 in Patients w/HER2-Expressing/Mutant Advanced or Metastatic Solid Tumors

SystImmune

NCT06714617

ACTIVE NOT RECRUITING Phase 2 119 participants

Vaccine to Prevent Recurrence in Patients With HER-2 Positive Breast Cancer

H. Lee Moffitt Cancer Center and Research Institute

NCT03384914

ACTIVE NOT RECRUITING NA 102 participants

Taking AIM at Breast Cancer

Dana-Farber Cancer Institute

NCT04720209

ACTIVE NOT RECRUITING 100 participants

The Differential Impact of Proton Beam Irradiation Versus Conventional Radiation on Organs-at-risk in Stage II-III Breast Cancer Patients

Massachusetts General Hospital

NCT03270072

ACTIVE NOT RECRUITING NA 60 participants

Ultrahypofractionation and Normal Tissue Toxicity

Massachusetts General Hospital

NCT05912231

ACTIVE NOT RECRUITING NA 34 participants

Safety of Lower Scalp Cooling Temperature to Prevent Hair Loss From Chemotherapy in Breast Cancer Patients

Memorial Sloan Kettering Cancer Center

NCT04180579

ACTIVE NOT RECRUITING NA 30 participants

CARE (Chemotherapy Alopecia REduction)

George Washington University

NCT07201389

ACTIVE NOT RECRUITING 23 participants

Study of Cardiopulmonary Exercise Testing in Women Who Have HER2-Positive Breast Cancer With Mild Cardiotoxicity

Memorial Sloan Kettering Cancer Center

NCT05036252

ACTIVE NOT RECRUITING NA 23 participants

Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors

Case Comprehensive Cancer Center

NCT06336538

COMPLETED Phase 2 52 participants

Effect of Omega 3 on Atrophic Vaginitis in Breast Cancer Survivors

Ohio State University Comprehensive Cancer Center

NCT02150525

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 7
Phase 3 1

Named interventions

Most-linked intervention names on Breast Cancer Stage III records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Questionnaire Administration Other
2 trials
Questionnaire administration Behavioral
1 trials
Accelerated Photon Radiation Therapy (XRT) Radiation
1 trials
Accelerated Proton Beam Radiation Therapy (PBT) Radiation
1 trials
Web-based decision aid Other
1 trials
PAXMAN Scalp Cooler Device
1 trials
BL-M17D1 Drug
1 trials
WOKVAC Vaccine Biological
1 trials

US sites by state

Facility locations filed on Breast Cancer Stage III trials. A trial with sites in several states counts in each.

New York 5 trials
Massachusetts 5 trials
Ohio 3 trials
Georgia 3 trials
Florida 3 trials
California 3 trials
Virginia 2 trials
Tennessee 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Breast Cancer Stage III page

22 registered trials, 10 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Breast Cancer Stage III condition card totals 22 registered trials; most-linked intervention Questionnaire Administration; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.