Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

ACTIVE NOT RECRUITING Phase 3

Axillary Reverse Mapping in Preventing Lymphedema in Patients With Breast Cancer Undergoing Axillary Lymph Node Dissection

NCT03927027 · View on ClinicalTrials.gov ↗

Study Summary

This phase III trial studies how well axillary reverse mapping works in preventing lymphedema in patients with breast cancer undergoing axillary lymph node dissection. Axillary reverse mapping may help to preserve the lymph node drainage system around the breast so as to prevent lymphedema after surgery.

Interventions

  • OTHER Quality-of-Life Assessment
  • OTHER Questionnaire Administration
  • DRUG Isosulfan Blue
  • PROCEDURE Axillary Lymph Node Dissection
  • PROCEDURE Mapping

Study Locations (20)

Florida

  • UM Sylvester Comprehensive Cancer Center at Coral Gables — Coral Gables
  • UM Sylvester Comprehensive Cancer Center at Deerfield Beach — Deerfield Beach
  • Holy Cross Hospital — Fort Lauderdale
  • University of Florida Health Science Center - Gainesville — Gainesville
  • Baptist MD Anderson Cancer Center — Jacksonville
  • Mayo Clinic in Florida — Jacksonville
  • University of Miami Miller School of Medicine-Sylvester Cancer Center — Miami
  • UM Sylvester Comprehensive Cancer Center at Kendall — Miami
  • Orlando Health Cancer Institute — Orlando
  • UM Sylvester Comprehensive Cancer Center at Plantation — Plantation

California

  • UC San Diego Moores Cancer Center — La Jolla
  • Contra Costa Regional Medical Center — Martinez
  • Alta Bates Summit Medical Center - Summit Campus — Oakland
  • Saint John's Cancer Institute — Santa Monica

Delaware

  • Beebe South Coastal Health Campus — Frankford
  • Helen F Graham Cancer Center — Newark
  • Christiana Care Health System-Christiana Hospital — Newark
  • Beebe Health Campus — Rehoboth Beach

Arkansas

  • University of Arkansas for Medical Sciences — Little Rock

Colorado

  • Shaw Cancer Center — Edwards

Trial Details

FieldValue
Enrollment Target 534 participants
Start Date 2019-07-29
Est. Completion 2027-01
Phase Phase 3

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03927027

The ClinicalTrials.gov registry entry for NCT03927027 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 534 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Alliance for Clinical Trials in Oncology, which has 147 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Breast Cancer Stage II appearing as the primary indexed condition, and to 5 interventions — of which Quality-of-Life Assessment is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03927027 reports 20 study locations spanning 5 distinct geographic areas — top geographies include Florida, California, Delaware. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03927027 about?

NCT03927027 is a clinical study titled "Axillary Reverse Mapping in Preventing Lymphedema in Patients With Breast Cancer Undergoing Axillary Lymph Node Dissection". This phase III trial studies how well axillary reverse mapping works in preventing lymphedema in patients with breast cancer undergoing axillary lymph node dissection. Axillary reverse mapping may help to preserve the lymph node drainage system around the breast so as to prevent lymphedema after sur...

What is the current status of trial NCT03927027?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 534 participants. The study started on 2019-07-29. Estimated completion is 2027-01.

What conditions does trial NCT03927027 study?

This clinical trial studies the following conditions: Breast Cancer Stage II, Breast Cancer Stage III, Breast Cancer Stage I. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03927027?

The interventions under investigation include: Quality-of-Life Assessment (OTHER), Questionnaire Administration (OTHER), Isosulfan Blue (DRUG), Axillary Lymph Node Dissection (PROCEDURE), Mapping (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03927027?

This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 147 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03927027 being conducted?

This trial has 20 study locations across Arkansas, California, Colorado, Delaware, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial