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NCT06006806 · ClinicalTrials.gov registry record · NA
Evaluation of Radiobiological Effects in Skin Toxicities for Breast Cancer Patients With Pencil Beam Scanning Proton Therapy
A NA study of Breast Cancer and Breast Cancer Stage II, sponsored by Covenant Health Cancer Center.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT06006806: Recruiting NA study of Breast Cancer and Breast Cancer Stage II, sponsored by Covenant Health Cancer Center.
NCT06006806 is a NA study of Breast Cancer and Breast Cancer Stage II that is actively recruiting participants, run by Covenant Health Cancer Center. The registered enrollment target is 100 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06006806, a NA study of Breast Cancer and Breast Cancer Stage II, is actively recruiting participants, sponsored by Covenant Health Cancer Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
This purpose of this study is to examine skin reactions (called radiation dermatitis) that occur during pencil beam scanning (PBS) proton therapy. The researchers will test a unique technique called "Spot Delete" to see if it can reduce skin reactions for breast patients treated with PBS. They will also use a special computer model to study how the energy of the proton beam (linear energy transfer) is related to these skin reactions. The study involves creating a treatment plan based on a CT scan, which helps guide the proton beam in the body. The clinical team uses this CT scan to find the best placement for the protons. The "Spot Delete" method prevents protons from stopping in the skin, which is thought to cause skin redness.
Primary Outcome
"Spot Delete" technique in proton therapy reduces radiation dermatitis in breast cancer patients compared to historical data from patients who underwent regular proton therapy without the technique. Assessed by photographs, questionnaires and assessment using CTCAE and Radiation Dermatitis Severity scoring system.
Conditions Studied
Interventions
- RADIATION Pencil Beam Scanning Proton Therapy
Study Locations (1)
Tennessee
- Thompson Proton Center - Knoxville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2023-07-07 |
| Est. Completion | 2030-07-07 |
| Phase | NA |
What NCT06006806 shows while recruiting
NCT06006806 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (96% lower).
The record links to 4 conditions, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which Pencil Beam Scanning Proton Therapy is the first listed.
NCT06006806 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT06006806 about?
NCT06006806 is a clinical study titled "Evaluation of Radiobiological Effects in Skin Toxicities for Breast Cancer Patients With Pencil Beam Scanning Proton Therapy". This purpose of this study is to examine skin reactions (called radiation dermatitis) that occur during pencil beam scanning (PBS) proton therapy. The researchers will test a unique technique called "Spot Delete" to see if it can reduce skin reactions for breast patients treated with PBS. They will ...
What is the current status of trial NCT06006806?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2023-07-07. Estimated completion is 2030-07-07.
What conditions does trial NCT06006806 study?
This clinical trial studies the following conditions: Breast Cancer, Breast Cancer Stage II, Breast Cancer Stage III, Breast Cancer Stage I.
What interventions are being tested in trial NCT06006806?
The interventions under investigation include: Pencil Beam Scanning Proton Therapy (RADIATION).
Who is sponsoring clinical trial NCT06006806?
This trial is sponsored by Covenant Health Cancer Center, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06006806 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06006806's enrollment target sits among peer trials
100 565th of 1224 higher than 630 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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