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NCT03270072 · ClinicalTrials.gov registry record
The Differential Impact of Proton Beam Irradiation Versus Conventional Radiation on Organs-at-risk in Stage II-III Breast Cancer Patients
A clinical trial of Breast Cancer Stage II and Breast Cancer Stage III, sponsored by Massachusetts General Hospital.
- Active
- Registry status
- 100
- Enrollment target
- 1
- Study location
NCT03270072: Active study of Breast Cancer Stage II and Breast Cancer Stage III, sponsored by Massachusetts General Hospital.
NCT03270072 is a study of Breast Cancer Stage II and Breast Cancer Stage III that is active but no longer recruiting, run by Massachusetts General Hospital. The registered enrollment target is 100 participants, below the 177-participant average among 22 other Breast Cancer Stage II trials with a reported enrollment target (44% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03270072, a study of Breast Cancer Stage II and Breast Cancer Stage III, is active but no longer recruiting, sponsored by Massachusetts General Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of the study is to serve as a correlative study for patients enrolled on the RadCOMP trial (NCT02603341), a randomized phase III study of stage II and III breast cancer patients treated with either conventional photon radiation or proton beam radiation
Primary Outcome
Comparison of the change in GLS between conventional radiation and proton beam radiation groups. Participants who decrease their GLS by at least 2% 6-8 months following radiation therapy will be considered to demonstrate a significant decrement in GLS.
Conditions Studied
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2017-10-26 |
| Est. Completion | 2026-12-31 |
What the registry record for NCT03270072 still lists
NCT03270072 is an observational study that tracks outcomes without assigning an intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 177-participant average among 22 other Breast Cancer Stage II trials with a reported enrollment target (44% lower).
The record links to 2 conditions, with Breast Cancer Stage II appearing as the primary indexed condition, and to 0 interventions.
NCT03270072 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT03270072 about?
NCT03270072 is a clinical study titled "The Differential Impact of Proton Beam Irradiation Versus Conventional Radiation on Organs-at-risk in Stage II-III Breast Cancer Patients". The objective of the study is to serve as a correlative study for patients enrolled on the RadCOMP trial (NCT02603341), a randomized phase III study of stage II and III breast cancer patients treated with either conventional photon radiation or proton beam radiation
What is the current status of trial NCT03270072?
This trial is currently active not recruiting. The enrollment target is 100 participants. The study started on 2017-10-26. Estimated completion is 2026-12-31.
What conditions does trial NCT03270072 study?
This clinical trial studies the following conditions: Breast Cancer Stage II, Breast Cancer Stage III.
Who is sponsoring clinical trial NCT03270072?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03270072 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer Stage II
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03270072's enrollment target sits among peer trials
100 8th of 22 higher than 13 of 22 other Breast Cancer Stage II trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer Stage II trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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