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ClinicalTrials.gov 8 recruiting now official registry

Brain Neoplasms clinical trials

8 of 15 indexed Brain Neoplasms trials are currently recruiting.

15 US clinical trials · 8 currently recruiting

Brain Neoplasms is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is University of Utah, running 2 of these trials.

The research picture

Brain Neoplasms has 15 registered US clinical trials, 8 of them open to new participants right now, about 53% of the total.

8
recruiting participants now
53%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
2
top sponsor: University of Utah
Phase 13Phase 21Phase 32Phase 41

Active & Recent Trials

15 total, page 1 of 1

RECRUITING 784 participants

The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)

Jasper Gerritsen

NCT06118723

RECRUITING 225 participants

The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma

Erasmus Medical Center

NCT06273176

RECRUITING NA 125 participants

HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)

Dartmouth-Hitchcock Medical Center

NCT06930846

RECRUITING Phase 1 124 participants

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

Pfizer

NCT05538130

RECRUITING Phase 1 73 participants

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Stemline Therapeutics

NCT05386108

RECRUITING NA 30 participants

Guided Meditation During Radiation Therapy for Brain Tumors

University of Utah

NCT06165653

RECRUITING NA 20 participants

Ommaya Reservoir Placement at the Time of Biopsy for Longitudinal Biomarker Collection in Patients With Brain Tumors

Mayo Clinic

NCT06322602

RECRUITING NA 8 participants

Intraoperative Fluorescence-Guided Aspirate Tissue Monitoring of 5-ALA During Brain Tumor Surgery

University of Illinois at Chicago

NCT07111182

ACTIVE NOT RECRUITING 400 participants

[18F]FET PET for Characterization of Progressive or Recurrent Glioma From Treatment Related Changes

Telix Pharmaceuticals (Innovations) Pty Limited

NCT07238322

COMPLETED Phase 3 716 participants

An Investigational Immuno-therapy Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)

Bristol-Myers Squibb

NCT02667587

COMPLETED Phase 3 550 participants

Study of Neurologic Progression With Motexafin Gadolinium and Radiation Therapy (SMART)

Pharmacyclics

NCT00054795

COMPLETED Phase 2 274 participants

Hypovitaminosis D in Neurocritical Patients

University of Utah

NCT02881957

COMPLETED Phase 4 130 participants

Surgery Versus Radiosurgery to Treat Metastatic Brain Tumors

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00075166

COMPLETED Phase 1 80 participants

A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases

AbbVie (prior sponsor, Abbott)

NCT00649207

COMPLETED 50 participants

(1)H-Nuclear Magnetic Resonance Spectroscopic Imaging of the Brain in Patients Who Receive Neurotoxic Therapy

National Cancer Institute (NCI)

NCT00001807

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 1
Phase 3 2
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Brain Neoplasms Trial Landscape

15 indexed Brain Neoplasms studies · 8 recruiting (53%).

Phase mix: 3 late (III/IV) vs 4 early (I/II).

Top sponsor: University of Utah (2 trials), 9 others listed. 15 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Brain Neoplasms?

PlainTrial tracks 15 US clinical trials for Brain Neoplasms, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Brain Neoplasms?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.