Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Brain Disease: later-stage trial registry
8 of 9 indexed Brain Disease trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #1,916 of 28,707 conditions by registered trial count.
9 US clinical trials · 8 currently recruiting · #1,916 of 28,707 conditions by registered trial count
Brain Disease: 9 US clinical trials tracked, 8 recruiting.
Brain Disease is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Neurological Disorders and Stroke (NINDS), running 4 of these trials.
Enrollment posture brief
Registry condition brain-disease
OPEN 8 | RECR 89% | LATE 1 | EARLY 0 | RANK #1916 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Acute Spinal Cord Injury (89% recruiting · 9 trials)
Brain Disease lists 8 open slots (89% of 9 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Brain Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Brain Disease is recruiting above its size-band peers.
8 of 9 indexed trials (88.9%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Brain Disease research.
National Institute of Neurological Disorders and Stroke (NINDS) accounts for 4 of 9 trials (44.4%). 5 distinct sponsors appear on at least one study for this condition label.
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Typical Brain Disease enrolment sits around 130 participants.
Median target enrolment is 130 among the 9 trials that report a genuine target (sentinel values excluded). 4 of those (44.4%) plan for fewer than 100 participants.
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Brain Disease splits between interventional and observational designs.
5 interventional and 4 observational studies make up this index (55.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
9 total, page 1 of 1
Natural History of Stroke: Cause and Development
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00009243
Inflammatory and Infectious Diseases of the Nervous System
National Institute of Neurological Disorders and Stroke (NINDS)
NCT02435810
Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke
National Institute of Neurological Disorders and Stroke (NINDS)
NCT06615973
SGC Stimulation, Perioperative Vascular Reactivity, and Organ Injury in Cardiac Surgery
Vanderbilt University Medical Center
NCT05812755
Brain Connections for Arm Movement After Stroke
VA Office of Research and Development
NCT04286516
Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function
Jorge Gonzalez-Martinez
NCT07056348
Clinical Translation of a Novel Brain PET Insert for Simultaneous PET/MR
Stanford University
NCT04383808
Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke
Jorge Gonzalez-Martinez
NCT06303869
Study of Abnormal Blood Clotting in Children With Stroke
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00001927
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Brain Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Brain Disease trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Brain Disease page
9 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 8 Brain Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- National Institute of Neurological Disorders and Stroke (NINDS) sponsors the most Brain Disease trials on record, review their full trial history before evaluating a specific study. See National Institute of Neurological Disorders and Stroke (NINDS)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Brain Disease condition card totals 9 registered trials; most-linked intervention Deep Brain Stimulation (DBS) of the Motor Thalamus; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.