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ClinicalTrials.gov 12 recruiting now official registry

Bladder Pain Syndrome clinical trials

12 of 14 indexed Bladder Pain Syndrome trials are currently recruiting.

14 US clinical trials · 12 currently recruiting

Bladder Pain Syndrome is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Walter Reed National Military Medical Center, running 3 of these trials.

The research picture

Bladder Pain Syndrome has 14 registered US clinical trials, 12 of them open to new participants right now, about 86% of the total.

12
recruiting participants now
86%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
3
top sponsor: Walter Reed National Military Medical Center
Phase 12Phase 22Phase 31Phase 41

Active & Recent Trials

14 total, page 1 of 1

RECRUITING 1,000 participants

Identifying Genetic Causes of IC/BPS

Boston Children's Hospital

NCT00389142

RECRUITING NA 240 participants

EPPIC: Easing Pelvic Pain Interventions Clinical Research Program

State University of New York at Buffalo

NCT05127616

RECRUITING NA 220 participants

Pain Type and Interstitial Cystitis/Bladder Pain Syndrome Treatment

Vanderbilt University Medical Center

NCT06299683

RECRUITING 159 participants

Effect of Intradetrusor onabotulinumtoxinA Injection Versus Conservative Management on Female Sexual Function in Patients With Bladder Pain Syndrome

Walter Reed National Military Medical Center

NCT06729151

RECRUITING Phase 2 120 participants

Safety and Efficacy Study of VNX001 Compared to Its Individual Components (Lidocaine and Heparin) or Placebo in Subjects With IC/BPS

Vaneltix Pharma

NCT05737121

RECRUITING Phase 4 100 participants

Bladder Botox UTI Antibiotic Prophylaxis

Walter Reed National Military Medical Center

NCT06387329

RECRUITING NA 75 participants

Investigation of PEMF Therapy for Female Patients With IC/BPS

Wake Forest University Health Sciences

NCT05149573

RECRUITING NA 50 participants

Motor Cortical Neuromodulation in Women With Interstitial Cystitis/Bladder Pain Syndrome

University of Southern California

NCT04734847

RECRUITING Phase 2 50 participants

Safety, Efficacy, and Frequency of Administration of VNX001 in the Treatment of Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS)

Vaneltix Pharma

NCT06394830

RECRUITING NA 38 participants

New Approaches to Nerve Stimulation Therapy for Bladder Pain Syndrome

Walter Reed National Military Medical Center

NCT06204874

RECRUITING NA 34 participants

Acupuncture First for IC/BPS

University Hospitals Cleveland Medical Center

NCT06366269

RECRUITING Early Phase 1 30 participants

Safety and Efficacy of Aloe Vera in the Management of the Symptoms of Interstitial Cystitis

Wake Forest University Health Sciences

NCT04734106

ACTIVE NOT RECRUITING Early Phase 1 5 participants

Transvaginal Botulinum Toxin A for Interstitial Cystitis / Bladder Pain Syndrome

Stanford University

NCT05485207

COMPLETED Phase 3 90 participants

Clinical Trial Comparing Two Bladder Instillations for IC/BPS

Olivia Cardenas-Trowers, M.D.

NCT03463915

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 2
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Bladder Pain Syndrome Trial Landscape

14 indexed Bladder Pain Syndrome studies · 12 recruiting (86%).

Phase mix: 2 late (III/IV) vs 4 early (I/II).

Top sponsor: Walter Reed National Military Medical Center (3 trials), 9 others listed. 14 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Bladder Pain Syndrome?

PlainTrial tracks 14 US clinical trials for Bladder Pain Syndrome, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Bladder Pain Syndrome?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.