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ClinicalTrials.gov 12 recruiting now early-phase tilt small index

Bladder Pain Syndrome: early-phase trial registry

12 of 14 indexed Bladder Pain Syndrome trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,230 of 28,707 conditions by registered trial count.

14 US clinical trials · 12 currently recruiting · #1,230 of 28,707 conditions by registered trial count

Bladder Pain Syndrome: 14 US clinical trials tracked, 12 recruiting.

Bladder Pain Syndrome is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Walter Reed National Military Medical Center, running 3 of these trials.

Enrollment posture brief

Registry condition bladder-pain-syndrome

OPEN 12 | RECR 86% | LATE 2 | EARLY 4 | RANK #1230 | SPON 3

Nearest open-share peer: Adenovirus (86% recruiting · 7 trials)

Bladder Pain Syndrome (this)86%Acute Respiratory Failure35.7%Adherence, Medication35.7%Acromegaly28.6%Abscess7.1%
Open-enrollment share among volume-matched conditions near Bladder Pain Syndrome

Bladder Pain Syndrome lists 12 open slots (86% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Bladder Pain Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Bladder Pain Syndrome is recruiting above its size-band peers.

    12 of 14 indexed trials (85.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Bladder Pain Syndrome research.

    Walter Reed National Military Medical Center accounts for 3 of 14 trials (21.4%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical Bladder Pain Syndrome enrolment sits around 90 participants.

    Median target enrolment is 90 among the 14 trials that report a genuine target (sentinel values excluded). 8 of those (57.1%) plan for fewer than 100 participants.

  4. Bladder Pain Syndrome research is mostly interventional.

    12 interventional and 2 observational studies make up this index (85.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 22Phase 31Phase 41

Open and recent trials

14 total, page 1 of 1

RECRUITING 1,000 participants

Identifying Genetic Causes of IC/BPS

Boston Children's Hospital

NCT00389142

RECRUITING NA 240 participants

EPPIC: Easing Pelvic Pain Interventions Clinical Research Program

State University of New York at Buffalo

NCT05127616

RECRUITING NA 220 participants

Pain Type and Interstitial Cystitis/Bladder Pain Syndrome Treatment

Vanderbilt University Medical Center

NCT06299683

RECRUITING 159 participants

Effect of Intradetrusor onabotulinumtoxinA Injection Versus Conservative Management on Female Sexual Function in Patients With Bladder Pain Syndrome

Walter Reed National Military Medical Center

NCT06729151

RECRUITING Phase 2 120 participants

Safety and Efficacy Study of VNX001 Compared to Its Individual Components (Lidocaine and Heparin) or Placebo in Subjects With IC/BPS

Vaneltix Pharma

NCT05737121

RECRUITING Phase 4 100 participants

Bladder Botox UTI Antibiotic Prophylaxis

Walter Reed National Military Medical Center

NCT06387329

RECRUITING NA 75 participants

Investigation of PEMF Therapy for Female Patients With IC/BPS

Wake Forest University Health Sciences

NCT05149573

RECRUITING NA 50 participants

Motor Cortical Neuromodulation in Women With Interstitial Cystitis/Bladder Pain Syndrome

University of Southern California

NCT04734847

RECRUITING Phase 2 50 participants

Safety, Efficacy, and Frequency of Administration of VNX001 in the Treatment of Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS)

Vaneltix Pharma

NCT06394830

RECRUITING NA 38 participants

New Approaches to Nerve Stimulation Therapy for Bladder Pain Syndrome

Walter Reed National Military Medical Center

NCT06204874

RECRUITING NA 34 participants

Acupuncture First for IC/BPS

University Hospitals Cleveland Medical Center

NCT06366269

RECRUITING Early Phase 1 30 participants

Safety and Efficacy of Aloe Vera in the Management of the Symptoms of Interstitial Cystitis

Wake Forest University Health Sciences

NCT04734106

ACTIVE NOT RECRUITING Early Phase 1 5 participants

Transvaginal Botulinum Toxin A for Interstitial Cystitis / Bladder Pain Syndrome

Stanford University

NCT05485207

COMPLETED Phase 3 90 participants

Clinical Trial Comparing Two Bladder Instillations for IC/BPS

Olivia Cardenas-Trowers, M.D.

NCT03463915

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 2
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Bladder Pain Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

VNX001 Drug
2 trials
Bladder instillation WITHOUT triamcinolone acetonide Drug
1 trials
Bladder instillation WITH triamcinolone acetonide Drug
1 trials
Transvaginal botulinum toxin A (BTA) injection Drug
1 trials
Conservative management (dietary and behavioral) Behavioral
1 trials
Onabotulinum toxin A Drug
1 trials
Behavioral management Behavioral
1 trials
Sham Pulsed Electromagnetic Field (PEMF) Device Device
1 trials

US sites by state

Facility locations filed on Bladder Pain Syndrome trials. A trial with sites in several states counts in each.

California 5 trials
North Carolina 3 trials
Maryland 3 trials
New York 2 trials
Massachusetts 2 trials
Georgia 2 trials
Tennessee 1 trials
Oregon 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Bladder Pain Syndrome page

14 registered trials, 12 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Bladder Pain Syndrome condition card totals 14 registered trials; most-linked intervention VNX001; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.