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NCT07189442 · ClinicalTrials.gov registry record · NA
L-theanine and Paraxanthine for Cognitive Improvement in Adults With ADHD and ASD
A NA study of Attention Deficit Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD), sponsored by Texas Tech University Health Sciences Center.
- Recruiting
- Registry status
- NA
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT07189442: Recruiting NA study of Attention Deficit Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD), sponsored by Texas Tech University Health Sciences Center.
NCT07189442 is a NA study of Attention Deficit Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD) that is actively recruiting participants, run by Texas Tech University Health Sciences Center. The registered enrollment target is 24 participants, below the 140-participant average among 18 other Attention Deficit Hyperactivity Disorder (ADHD) trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07189442, a NA study of Attention Deficit Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD), is actively recruiting participants, sponsored by Texas Tech University Health Sciences Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
This pilot study will test whether combining L-theanine and paraxanthine improves sustained attention, inhibitory control, and overall cognition in adults with ADHD and ASD. Two parallel randomized, single-blinded, repeated-measures crossover trials will be conducted. Participants will complete neuropsychological testing, fMRI scanning, and self-report measures following administration of the L-theanine-paraxanthine combination compared to placebo.
Primary Outcome
fMRI task-related activity in default mode and central executive networks during Go/NoGo and Stop-Signal tasks.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Placebo
- DIETARY_SUPPLEMENT L-theanine and paraxanthine
Study Locations (1)
Texas
- Texas Tech University - Lubbock
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2025-10-01 |
| Est. Completion | 2026-06-01 |
| Phase | NA |
What NCT07189442 shows while recruiting
NCT07189442 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 140-participant average among 18 other Attention Deficit Hyperactivity Disorder (ADHD) trials with a reported enrollment target (83% lower).
The record links to 2 conditions, with Attention Deficit Hyperactivity Disorder (ADHD) appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07189442 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT07189442 about?
NCT07189442 is a clinical study titled "L-theanine and Paraxanthine for Cognitive Improvement in Adults With ADHD and ASD". This pilot study will test whether combining L-theanine and paraxanthine improves sustained attention, inhibitory control, and overall cognition in adults with ADHD and ASD. Two parallel randomized, single-blinded, repeated-measures crossover trials will be conducted. Participants will complete neur...
What is the current status of trial NCT07189442?
This trial is currently recruiting. It is a NA study. The enrollment target is 24 participants. The study started on 2025-10-01. Estimated completion is 2026-06-01.
What conditions does trial NCT07189442 study?
This clinical trial studies the following conditions: Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD).
What interventions are being tested in trial NCT07189442?
The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), L-theanine and paraxanthine (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT07189442?
This trial is sponsored by Texas Tech University Health Sciences Center, which has 76 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07189442 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Attention Deficit Hyperactivity Disorder (ADHD)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07189442's enrollment target sits among peer trials
24 17th of 18 higher than 1 of 18 other Attention Deficit Hyperactivity Disorder (ADHD) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Attention Deficit Hyperactivity Disorder (ADHD) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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