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ClinicalTrials.gov 40 recruiting now early-phase tilt

Anatomic Stage II Breast Cancer AJCC v8: early-phase trial registry

40 of 74 indexed Anatomic Stage II Breast Cancer AJCC v8 trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #183 of 28,707 conditions by registered trial count.

74 US clinical trials · 40 currently recruiting · #183 of 28,707 conditions by registered trial count

Anatomic Stage II Breast Cancer AJCC v8: 74 US clinical trials tracked, 40 recruiting.

Anatomic Stage II Breast Cancer AJCC v8 is the subject of 74 registered US clinical trials on ClinicalTrials.gov, 40 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 12 of these trials.

Enrollment posture brief

Registry condition anatomic-stage-ii-breast-cancer-ajcc-v8

OPEN 40 | RECR 54% | LATE 9 | EARLY 26 | RANK #183 | SPON 12

Nearest open-share peer: Mental Health (54% recruiting · 63 trials)

Chronic Kidney Diseases62.2%Anatomic Stage II Breast (this)Anatomic Stage II Breast (th…54%Chronic Myelomonocytic Leuke40.5%Anemia18.9%HIV Infection12.2%
Open-enrollment share among volume-matched conditions near Anatomic Stage II Breast Cancer AJCC v8

Anatomic Stage II Breast Cancer AJCC v8 lists 40 open slots (54% of 74 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Anatomic Stage II Breast Cancer AJCC v8 on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Anatomic Stage II Breast Cancer AJCC v8 is recruiting above its size-band peers.

    40 of 74 indexed trials (54.1%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Anatomic Stage II Breast Cancer AJCC v8 research.

    M.D. Anderson Cancer Center accounts for 12 of 74 trials (16.2%). 22 distinct sponsors appear on at least one study for this condition label.

  3. Typical Anatomic Stage II Breast Cancer AJCC v8 enrolment sits around 88 participants.

    Median target enrolment is 88 among the 74 trials that report a genuine target (sentinel values excluded). 39 of those (52.7%) plan for fewer than 100 participants.

  4. Anatomic Stage II Breast Cancer AJCC v8 research is mostly interventional.

    66 interventional and 8 observational studies make up this index (89.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 18Phase 218Phase 38Phase 41

Open and recent trials

74 total, page 2 of 2

ACTIVE NOT RECRUITING NA 256 participants

Culturally Based Brief Expressive Writing Intervention for the Improvement of Health in Chinese Immigrant Stage 0-III Breast Cancer Survivors, Writing to Heal Study

M.D. Anderson Cancer Center

NCT04754412

ACTIVE NOT RECRUITING Phase 2 249 participants

Taxane and Taxane-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer

ECOG-ACRIN Cancer Research Group

NCT04001829

ACTIVE NOT RECRUITING Phase 2 235 participants

Testing the Role of FDG-PET/CT to Predict Response to Therapy Prior to Surgery for HER2-positive Breast Cancer, The DIRECT Trial

ECOG-ACRIN Cancer Research Group

NCT05710328

ACTIVE NOT RECRUITING Phase 3 146 participants

Phase III Study of 5tx vs 15tx of RT (X-rays or Protons) Including RNI in Breast Cancer Patients

Mayo Clinic

NCT04443413

ACTIVE NOT RECRUITING Phase 2 120 participants

Metformin and Nightly Fasting in Women With Early Breast Cancer

M.D. Anderson Cancer Center

NCT05023967

ACTIVE NOT RECRUITING Phase 2 120 participants

Ph2 Study for Optimization of Adjunct Systemic Therapy in HER2+ Patients, MolecularPCR Trial

M.D. Anderson Cancer Center

NCT07407920

ACTIVE NOT RECRUITING NA 103 participants

Radiation Therapy Boost Before Surgery for the Treatment of Non-metastatic Breast Cancer

Rutgers, The State University of New Jersey

NCT04871516

ACTIVE NOT RECRUITING NA 95 participants

Identifying Decision Making Needs for Older Adult Women With Stage I-III Breast Cancer Considering Neoadjuvant or Adjuvant Chemotherapy

M.D. Anderson Cancer Center

NCT05049746

ACTIVE NOT RECRUITING NA 62 participants

Standard Verbal Counseling With or Without a Pictorial Educational Tool for the Reduction of Psychological Morbidity in Patients With Stage 0-IIIA Breast Cancer Receiving Radiation Therapy, COPE Study

OHSU Knight Cancer Institute

NCT04993313

ACTIVE NOT RECRUITING NA 61 participants

Intensity Modulated Radiation Therapy or 3-Dimensional Conformal Radiation Therapy in Treating Patients With Lymph-Node Positive Breast Cancer

Ohio State University Comprehensive Cancer Center

NCT03786354

ACTIVE NOT RECRUITING NA 60 participants

A Conversational Agent (Cecebot) to Improve Insomnia in Stage I-III Breast Cancer Survivors

University of Washington

NCT06392789

ACTIVE NOT RECRUITING NA 49 participants

Mindfulness Intervention for Improving Nutrition in the Digital Kitchen Among Stage I-III Breast Cancer Survivors, MIND Trial

Fred Hutchinson Cancer Center

NCT06643455

ACTIVE NOT RECRUITING Phase 2 33 participants

STEMVAC in Patients With Early Stage Triple Negative Breast Cancer

University of Washington

NCT05455658

ACTIVE NOT RECRUITING NA 30 participants

Exercise During Chemotherapy in Older Women With Stage I-III Breast Cancer

M.D. Anderson Cancer Center

NCT05025059

ACTIVE NOT RECRUITING NA 4 participants

Prospective Pilot Study of Robot-assisted Nipple Sparing Mastectomy (RNSM)

Ohio State University Comprehensive Cancer Center

NCT04537312

COMPLETED NA 452 participants

Tibetan Yoga in Improving Fatigue and Sleep in Participants With Stage I-III Breast Cancer

M.D. Anderson Cancer Center

NCT00507923

COMPLETED Phase 2 130 participants

Safely Stopping Pre-medications in Patients With Breast Cancer Who Are Receiving Paclitaxel

Ohio State University Comprehensive Cancer Center

NCT04862585

COMPLETED NA 50 participants

An Episodic Future Thinking Intervention to Promote Weight Loss in Breast Cancer Survivors

Ohio State University Comprehensive Cancer Center

NCT05012176

COMPLETED NA 45 participants

An Escape Room Intervention to Help Improve Breast Cancer Patients' Ability to Navigate Online Access to Nutrition Information

Fred Hutchinson Cancer Center

NCT06193070

COMPLETED NA 27 participants

Weight Bearing Exercise in Preventing Frailty in Stage I-IIIA Breast Cancer Survivors

University of Arizona

NCT03708055

COMPLETED NA 23 participants

Acupuncture in Reducing Chemotherapy-Induced Peripheral Neuropathy in Participants With Stage I-III Breast Cancer

Wake Forest University Health Sciences

NCT03505671

COMPLETED Phase 1 20 participants

M7824 in Treating Patients With Stage II-III HER2 Positive Breast Cancer

M.D. Anderson Cancer Center

NCT03620201

COMPLETED Phase 1 15 participants

Hydroxychloroquine, Palbociclib, and Letrozole Before Surgery in Treating Patients With Estrogen Receptor Positive, HER2 Negative Breast Cancer

M.D. Anderson Cancer Center

NCT03774472

COMPLETED Phase 1 11 participants

Nilotinib in Preventing Paclitaxel-Induced Peripheral Neuropathy in Patients With Stage I-III Breast Cancer

Ohio State University Comprehensive Cancer Center

NCT04205903

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Phase Distribution

PhaseTrial count
Phase 1 8
Phase 2 18
Phase 3 8
Phase 4 1

Named interventions

Most-linked intervention names on Anatomic Stage II Breast Cancer AJCC v8 records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Questionnaire Administration Other
31 trials
Biospecimen Collection Procedure
20 trials
Quality-of-Life Assessment Other
14 trials
Best Practice Other
10 trials
Survey Administration Other
9 trials
Educational Intervention Other
8 trials
Docetaxel Drug
6 trials
Paclitaxel Drug
5 trials

US sites by state

Facility locations filed on Anatomic Stage II Breast Cancer AJCC v8 trials. A trial with sites in several states counts in each.

California 21 trials
Arizona 15 trials
Ohio 13 trials
Texas 12 trials
Arkansas 8 trials
Alabama 8 trials
Washington 7 trials
Florida 7 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Anatomic Stage II Breast Cancer AJCC v8 page

74 registered trials, 40 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 40 Anatomic Stage II Breast Cancer AJCC v8 trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • M.D. Anderson Cancer Center sponsors the most Anatomic Stage II Breast Cancer AJCC v8 trials on record, review their full trial history before evaluating a specific study. See M.D. Anderson Cancer Center's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Anatomic Stage II Breast Cancer AJCC v8 condition card totals 74 registered trials; most-linked intervention Questionnaire Administration; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.