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ClinicalTrials.gov 11 recruiting now early-phase tilt

Aggression: early-phase trial registry

11 of 22 indexed Aggression trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #756 of 28,707 conditions by registered trial count.

22 US clinical trials · 11 currently recruiting · #756 of 28,707 conditions by registered trial count

Aggression: 22 US clinical trials tracked, 11 recruiting.

Aggression is the subject of 22 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Rutgers, The State University of New Jersey, running 5 of these trials.

Enrollment posture brief

Registry condition aggression

OPEN 11 | RECR 50% | LATE 2 | EARLY 4 | RANK #756 | SPON 5

Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)

Advanced Melanoma63.6%Aggression (this)50%Acute Myeloid Leukemia Arisi18.2%Adenocarcinoma of the Prosta0%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Aggression

Aggression lists 11 open slots (50% of 22 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Aggression on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Aggression is recruiting above its size-band peers.

    11 of 22 indexed trials (50%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Aggression research.

    Rutgers, The State University of New Jersey accounts for 5 of 22 trials (22.7%). 17 distinct sponsors appear on at least one study for this condition label.

  3. Typical Aggression enrolment sits around 60 participants.

    Median target enrolment is 60 among the 22 trials that report a genuine target (sentinel values excluded). 13 of those (59.1%) plan for fewer than 100 participants.

  4. Aggression research is mostly interventional.

    21 interventional and 1 observational studies make up this index (95.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 23Phase 31Phase 41

Open and recent trials

22 total, page 1 of 1

RECRUITING NA 400 participants

Just-In-Time Intervention to Reduce Alcohol-Facilitated Intimate Partner Violence Perpetration

Georgia State University

NCT05145868

RECRUITING 250 participants

Addressing Root Causes for Gun Violence Prevention (ARC-GVP)

University of Michigan

NCT05887973

RECRUITING NA 204 participants

Manage Emotions to Reduce Aggression (MERA)

VA Office of Research and Development

NCT04793776

RECRUITING Phase 2 164 participants

Clinical Trial on Agitation in Alzheimer's Dementia

IGC Pharma

NCT05543681

RECRUITING Phase 2 60 participants

Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism

Jeremy Veenstra-vanderweele

NCT07091279

RECRUITING NA 58 participants

A Virtual Reality Mindfulness Application for Aggression in Schizophrenia

Manhattan Psychiatric Center

NCT07434479

RECRUITING NA 40 participants

Treatment of Chronic Anger and Aggression Following Military-Related Betrayal

The University of Texas Health Science Center at San Antonio

NCT06609330

RECRUITING NA 40 participants

Basic and Applied Research on Extinction Bursts

Rutgers, The State University of New Jersey

NCT05925101

RECRUITING NA 30 participants

Manualized Assessment and Treatment Model of Challenging Behavior

Rutgers, The State University of New Jersey

NCT05928247

RECRUITING NA 30 participants

Extensions of Resurgence as Choice

Rutgers, The State University of New Jersey

NCT05537610

RECRUITING NA 24 participants

Refinements of Functional Communication Training

Rutgers, The State University of New Jersey

NCT04045600

ACTIVE NOT RECRUITING NA 65 participants

Behavior Therapy for Irritability in Autism

Yale University

NCT04654260

COMPLETED NA 939 participants

Social Ecology and the Prevention of Suicide and Aggression in African American Youth

DePaul University

NCT03954457

COMPLETED NA 335 participants

Healthy Brains & Behavior: Understanding and Treating Youth Aggression

University of Pennsylvania

NCT00842439

COMPLETED Phase 4 180 participants

Antipsychotic Discontinuation in Alzheimer's Disease

New York State Psychiatric Institute

NCT00417482

COMPLETED NA 165 participants

Hostile Bias Modification Training (HBMT) Study

Walter Reed Army Institute of Research (WRAIR)

NCT04997356

COMPLETED Phase 3 144 participants

Effectiveness of Treatment for Relational Aggression in Urban African American Girls

Children's Hospital of Philadelphia

NCT00510094

COMPLETED NA 40 participants

The Peace of Mind and Body Project: Treatment Development of Yoga for Anger Management in Incarcerated Adults

Brown University

NCT05336123

COMPLETED NA 32 participants

The Effect of Repeated Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior

University of Pennsylvania

NCT02674516

COMPLETED NA 30 participants

Identifying Precursors to Severe Problem Behavior

Hugo W. Moser Research Institute at Kennedy Krieger

NCT04097431

COMPLETED Phase 1 20 participants

Reducing Aggression in Children and Adolescent on an Inpatient Unit

Gonzalez-Heydrich, Joseph, M.D.

NCT01377948

COMPLETED Phase 2 8 participants

Propranolol for Challenging Behaviors in Autism

Rutgers, The State University of New Jersey

NCT04047355

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 3
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Aggression records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Propranolol Drug
2 trials
Other training Behavioral
1 trials
Hostile Bias Modification Training Behavioral
1 trials
NUT Dietary supplement
1 trials
CBI Behavioral
1 trials
ACT with RAGE-Control Behavioral
1 trials
Hatha Yoga Behavioral
1 trials
Psychoeducational attention control intervention Behavioral
1 trials

US sites by state

Facility locations filed on Aggression trials. A trial with sites in several states counts in each.

New Jersey 5 trials
New York 4 trials
Texas 3 trials
Pennsylvania 3 trials
Maryland 3 trials
Rhode Island 2 trials
Florida 2 trials
Connecticut 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Aggression page

22 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Aggression condition card totals 22 registered trials; most-linked intervention Propranolol; top US site state New Jersey. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.