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2026 data Public-data reference. official source

Aggression

Open-data reference.

22 US clinical trials · 11 currently recruiting

Active & Recent Trials

RECRUITING NA 400 participants

Just-In-Time Intervention to Reduce Alcohol-Facilitated Intimate Partner Violence Perpetration

Georgia State University

NCT05145868

RECRUITING 250 participants

Addressing Root Causes for Gun Violence Prevention (ARC-GVP)

University of Michigan

NCT05887973

RECRUITING NA 204 participants

Manage Emotions to Reduce Aggression (MERA)

VA Office of Research and Development

NCT04793776

RECRUITING Phase 2 164 participants

Clinical Trial on Agitation in Alzheimer's Dementia

IGC Pharma

NCT05543681

RECRUITING Phase 2 60 participants

Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism

Jeremy Veenstra-vanderweele

NCT07091279

RECRUITING NA 58 participants

A Virtual Reality Mindfulness Application for Aggression in Schizophrenia

Manhattan Psychiatric Center

NCT07434479

RECRUITING NA 40 participants

Treatment of Chronic Anger and Aggression Following Military-Related Betrayal

The University of Texas Health Science Center at San Antonio

NCT06609330

RECRUITING NA 40 participants

Basic and Applied Research on Extinction Bursts

Rutgers, The State University of New Jersey

NCT05925101

RECRUITING NA 30 participants

Manualized Assessment and Treatment Model of Challenging Behavior

Rutgers, The State University of New Jersey

NCT05928247

RECRUITING NA 30 participants

Extensions of Resurgence as Choice

Rutgers, The State University of New Jersey

NCT05537610

RECRUITING NA 24 participants

Refinements of Functional Communication Training

Rutgers, The State University of New Jersey

NCT04045600

ACTIVE NOT RECRUITING NA 65 participants

Behavior Therapy for Irritability in Autism

Yale University

NCT04654260

COMPLETED NA 939 participants

Social Ecology and the Prevention of Suicide and Aggression in African American Youth

DePaul University

NCT03954457

COMPLETED NA 335 participants

Healthy Brains & Behavior: Understanding and Treating Youth Aggression

University of Pennsylvania

NCT00842439

COMPLETED Phase 4 180 participants

Antipsychotic Discontinuation in Alzheimer's Disease

New York State Psychiatric Institute

NCT00417482

COMPLETED NA 165 participants

Hostile Bias Modification Training (HBMT) Study

Walter Reed Army Institute of Research (WRAIR)

NCT04997356

COMPLETED Phase 3 144 participants

Effectiveness of Treatment for Relational Aggression in Urban African American Girls

Children's Hospital of Philadelphia

NCT00510094

COMPLETED NA 40 participants

The Peace of Mind and Body Project: Treatment Development of Yoga for Anger Management in Incarcerated Adults

Brown University

NCT05336123

COMPLETED NA 32 participants

The Effect of Repeated Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior

University of Pennsylvania

NCT02674516

COMPLETED NA 30 participants

Identifying Precursors to Severe Problem Behavior

Hugo W. Moser Research Institute at Kennedy Krieger

NCT04097431

COMPLETED Phase 1 20 participants

Reducing Aggression in Children and Adolescent on an Inpatient Unit

Gonzalez-Heydrich, Joseph, M.D.

NCT01377948

COMPLETED Phase 2 8 participants

Propranolol for Challenging Behaviors in Autism

Rutgers, The State University of New Jersey

NCT04047355

Phase Distribution

PhaseTrial count
Early Phase 1 1
Phase 2 3
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Aggression Trial Landscape

ClinicalTrials.gov lists 22 US studies indexed under Aggression, and 11 of those are currently open to recruitment — roughly 50% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Aggression shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Aggression is led by Rutgers, The State University of New Jersey with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 22 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Aggression?

PlainTrial tracks 22 US clinical trials for Aggression, of which 11 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Aggression?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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