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NCT07091279 · ClinicalTrials.gov registry record · Phase 2

Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism

A Phase 2 study of Autism Spectrum Disorder and Aggression, sponsored by Jeremy Veenstra-vanderweele.

Recruiting
Registry status
Phase 2
Development phase
60
Enrollment target
2
Study locations

NCT07091279 is a Phase 2 study of Autism Spectrum Disorder and Aggression that is actively recruiting participants, run by Jeremy Veenstra-vanderweele. The registered enrollment target is 60 participants, below the 135-participant average among 224 other Autism Spectrum Disorder trials with a reported enrollment target (56% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT07091279, a Phase 2 study of Autism Spectrum Disorder and Aggression, is actively recruiting participants, sponsored by Jeremy Veenstra-vanderweele.

RECRUITING
Registry status
Phase 2
Development phase
60 participants
Enrollment target
2
Study locations

Study Summary

The goal of this clinical trial is to learn if propranolol can help reduce challenging behaviors associated with Autism Spectrum Disorder, including aggression, self-injury, and severe disruptive behaviors. Participants will be randomly assigned to receive either propranolol or a placebo (a look-alike substance that contains no drug) daily for 12 weeks. After the 12 weeks, all participants will have the opportunity to receive propranolol for an additional 12 weeks.

Interventions

  • DRUG Placebo
  • DRUG Propranolol

Study Locations (2)

New York

  • New York State Institute for Basic Research (IBR) - Staten Island
  • Center for Autism and the Developing Brain - White Plains

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2026-01-22
Est. Completion 2028-12
Phase Phase 2

Sponsor

Jeremy Veenstra-vanderweele

1 total trials

What the Registry Record Tells You About NCT07091279

The ClinicalTrials.gov registry entry for NCT07091279 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 135-participant average among 224 other Autism Spectrum Disorder trials with a reported enrollment target (56% lower). The listed sponsor is Jeremy Veenstra-vanderweele, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Autism Spectrum Disorder appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT07091279 reports 2 study locations spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT07091279 about?

NCT07091279 is a clinical study titled "Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism". The goal of this clinical trial is to learn if propranolol can help reduce challenging behaviors associated with Autism Spectrum Disorder, including aggression, self-injury, and severe disruptive behaviors. Participants will be randomly assigned to receive either propranolol or a placebo (a look-ali...

What is the current status of trial NCT07091279?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2026-01-22. Estimated completion is 2028-12.

What conditions does trial NCT07091279 study?

This clinical trial studies the following conditions: Autism Spectrum Disorder, Aggression, Self-Injury, Challenging Behaviour, Severe Disruptive Behaviour Disorders.

What interventions are being tested in trial NCT07091279?

The interventions under investigation include: Placebo (DRUG), Propranolol (DRUG).

Who is sponsoring clinical trial NCT07091279?

This trial is sponsored by Jeremy Veenstra-vanderweele, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07091279 being conducted?

This trial has 2 study locations across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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