Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00842439 · ClinicalTrials.gov registry record · NA
Healthy Brains & Behavior: Understanding and Treating Youth Aggression
A NA study of Aggression, sponsored by University of Pennsylvania.
- Completed
- Registry status
- NA
- Development phase
- 335
- Enrollment target
- 1
- Study location
NCT00842439: Completed NA study of Aggression, sponsored by University of Pennsylvania.
NCT00842439 is a NA study of Aggression that has completed, run by University of Pennsylvania. The registered enrollment target is 335 participants, above the 139-participant average among 21 other Aggression trials with a reported enrollment target (141% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00842439, a NA study of Aggression, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- NA
- Development phase
- 335 participants
- Enrollment target
- 1
- Study location
Study Summary
Understanding the joint neurobiological and social bases to aggression is critical to future attempts to tackle this major public health problem. The overarching goals are: (a) to conduct perhaps the most systematic integration of biosocial risk factors for childhood aggression in order to predict later aggression, (b) to conduct one of the very few biosocial interventions on childhood aggression, (c) to predict and treat two fundamentally different manifestations of aggression proactive and reactive aggression which likely have different etiologies and responsiveness to treatment. The specific aims are: (1) to assess biological (genetic, neurocognitive, brain imaging, neuroendocrinological, neurotoxin, psychophysiological, nutritional), psychosocial (neighborhood, family, school, peer, psychological) and psychiatric (ADHD, CD, ODD, depression, anxiety, PTSD, schizophrenia-spectrum) risk factors for male and female aggression in order to better predict later aggression, (2) to improve prediction by identifying the genetic, neuroimaging, psychophysiological, and neuroendocrinological factors that protect children who are socially at risk for a violence outcome, (3) to develop a genetic mouse model of aggression to test the effectiveness of nutritional interventions in reducing aggression, (4) to begin to develop a new biosocial approach to the treatment and prevention of aggression, based on both cognitive-behavioral and nutrition interventions, (5) to assess the differential prediction and treatment of two fundamental variants of child aggression: proactive and reactive aggression. The human sample will consist of 500 male and female 11-year-old children drawn from high-risk communities in Philadelphia. Three hundred participants will engage in a baseline assessment for risk factors for aggression, and then be randomly assigned to one of four three-month intervention programs: treatment-as-usual, cognitive-behavioral intervention, nutrition supplementation, or CBI +
Conditions Studied
Interventions
- BEHAVIORAL CBI
- DIETARY_SUPPLEMENT NUT
Study Locations (1)
Pennsylvania
- University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 335 participants |
| Start Date | 2009-02 |
| Est. Completion | 2012-08 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00842439
The ClinicalTrials.gov registry entry for NCT00842439 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 335 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 139-participant average among 21 other Aggression trials with a reported enrollment target (141% higher). The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Aggression appearing as the primary indexed condition, and to 2 interventions - of which CBI is the first listed.
NCT00842439 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT00842439 about?
NCT00842439 is a clinical study titled "Healthy Brains & Behavior: Understanding and Treating Youth Aggression". Understanding the joint neurobiological and social bases to aggression is critical to future attempts to tackle this major public health problem. The overarching goals are: (a) to conduct perhaps the most systematic integration of biosocial risk factors for childhood aggression in order to predict l...
What is the current status of trial NCT00842439?
This trial is currently completed. It is a NA study. The enrollment target is 335 participants. The study started on 2009-02. Estimated completion is 2012-08.
What conditions does trial NCT00842439 study?
This clinical trial studies the following conditions: Aggression.
What interventions are being tested in trial NCT00842439?
The interventions under investigation include: CBI (BEHAVIORAL), NUT (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT00842439?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00842439 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Aggression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Manage Emotions to Reduce Aggression (MERA)
RECRUITING · NA
-
Manualized Assessment and Treatment Model of Challenging Behavior
RECRUITING · NA
-
Refinements of Functional Communication Training
RECRUITING · NA
-
Treatment of Chronic Anger and Aggression Following Military-Related Betrayal
RECRUITING · NA
-
A Virtual Reality Mindfulness Application for Aggression in Schizophrenia
RECRUITING · NA
-
Basic and Applied Research on Extinction Bursts
RECRUITING · NA
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.