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NCT07434479 · ClinicalTrials.gov registry record · NA
A Virtual Reality Mindfulness Application for Aggression in Schizophrenia
A NA study of Aggression and Schizophrenia Disorder, sponsored by Manhattan Psychiatric Center.
- Recruiting
- Registry status
- NA
- Development phase
- 58
- Enrollment target
- 2
- Study locations
NCT07434479 is a NA study of Aggression and Schizophrenia Disorder that is actively recruiting participants, run by Manhattan Psychiatric Center. The registered enrollment target is 58 participants, below the 152-participant average among 21 other Aggression trials with a reported enrollment target (62% lower). The trial reports 2 study locations across 1 state.
The verdict
NCT07434479, a NA study of Aggression and Schizophrenia Disorder, is actively recruiting participants, sponsored by Manhattan Psychiatric Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 58 participants
- Enrollment target
- 2
- Study locations
Study Summary
The study investigates whether a virtual reality-based mindfulness based intervention can reduce impulsive aggression in individuals with schizophrenia or schizoaffective disorder. The primary goal is to evaluate whether mindfulness delivered via VR (MBI-VR) improves emotion regulation and engages the dorsomedial prefrontal cortex (dmPFC), a brain region involved in cognitive control and regulation of emotional responses. The study also examines whether these effects show a dose-related relationship. Participants will be randomized to receive different doses of MBI-VR intervention or distraction tasks and will complete repeated mindfulness VR sessions. Brain activity will be measured using functional magnetic resonance imaging (fMRI) during an emotion regulation task, along with clinical assessments of impulsive aggression related symptoms.
Conditions Studied
Interventions
- OTHER Mindfulness-Based Virtual Reality Intervention
Study Locations (2)
New York
- Manhattan Psychiatric Center - New York
- NewYork-Presbyterian/Weill Cornell Medical Center Westchester Division - White Plains
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 58 participants |
| Start Date | 2026-03-02 |
| Est. Completion | 2027-12-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07434479
The ClinicalTrials.gov registry entry for NCT07434479 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 58 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 152-participant average among 21 other Aggression trials with a reported enrollment target (62% lower). The listed sponsor is Manhattan Psychiatric Center, which has 7 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Aggression appearing as the primary indexed condition, and to 1 intervention - of which Mindfulness-Based Virtual Reality Intervention is the first listed.
NCT07434479 reports 2 study locations spanning 1 distinct geographic area - top geographies include New York.
Frequently Asked Questions
What is clinical trial NCT07434479 about?
NCT07434479 is a clinical study titled "A Virtual Reality Mindfulness Application for Aggression in Schizophrenia". The study investigates whether a virtual reality-based mindfulness based intervention can reduce impulsive aggression in individuals with schizophrenia or schizoaffective disorder. The primary goal is to evaluate whether mindfulness delivered via VR (MBI-VR) improves emotion regulation and engages t...
What is the current status of trial NCT07434479?
This trial is currently recruiting. It is a NA study. The enrollment target is 58 participants. The study started on 2026-03-02. Estimated completion is 2027-12-31.
What conditions does trial NCT07434479 study?
This clinical trial studies the following conditions: Aggression, Schizophrenia Disorder, Schizoaffecitve Disorder.
What interventions are being tested in trial NCT07434479?
The interventions under investigation include: Mindfulness-Based Virtual Reality Intervention (OTHER).
Who is sponsoring clinical trial NCT07434479?
This trial is sponsored by Manhattan Psychiatric Center, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07434479 being conducted?
This trial has 2 study locations across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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