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NCT02641691 · ClinicalTrials.gov registry record · Phase 2
Non-Operative Radiation Management of Adenocarcinoma of the Lower Rectum
A Phase 2 study of Rectal Cancer and Adenocarcinoma of the Rectum, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT02641691: Completed Phase 2 study of Rectal Cancer and Adenocarcinoma of the Rectum, sponsored by Washington University School of Medicine.
NCT02641691 is a Phase 2 study of Rectal Cancer and Adenocarcinoma of the Rectum that has completed, run by Washington University School of Medicine. The registered enrollment target is 20 participants, below the 3,167-participant average among 70 other Rectal Cancer trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02641691, a Phase 2 study of Rectal Cancer and Adenocarcinoma of the Rectum, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research study is to look at how tumors responds to a short course of radiation (5 days) followed by 8 cycles of chemotherapy.
Primary Outcome
* Criteria for complete clinical response: * No residual gross tumor at procto/sigmoidoscopy, or only erythematous scar or ulcer * No radiographic evidence of tumor on DRE * Substantial downsizing on MRI * No suspicious mesorectal lymph nodes on MRI * Negative biopsy from scar, ulcer, or former tumor site (if necessary according to surgeon's judgment) * Criteria for no significant clinical response: * Residual disease by DRE, endoscopy or MR. * Increase in primary tumor size upon
Conditions Studied
Interventions
- DRUG Fluorouracil
- DRUG Leucovorin
- DRUG Oxaliplatin
- RADIATION Radiation
Study Locations (1)
Missouri
- Washington University School of Medicine - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2016-05-27 |
| Est. Completion | 2020-03-29 |
| Phase | Phase 2 |
What the finished NCT02641691 record still lists
NCT02641691 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 3,167-participant average among 70 other Rectal Cancer trials with a reported enrollment target (99% lower).
The record links to 7 conditions, with Rectal Cancer appearing as the primary indexed condition, and to 4 interventions - of which Fluorouracil is the first listed.
NCT02641691 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT02641691 about?
NCT02641691 is a clinical study titled "Non-Operative Radiation Management of Adenocarcinoma of the Lower Rectum". The purpose of this research study is to look at how tumors responds to a short course of radiation (5 days) followed by 8 cycles of chemotherapy.
What is the current status of trial NCT02641691?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2016-05-27. Estimated completion is 2020-03-29.
What conditions does trial NCT02641691 study?
This clinical trial studies the following conditions: Rectal Cancer, Adenocarcinoma of the Rectum, Rectum Cancer, Cancer of Rectum, Cancer of the Rectum.
What interventions are being tested in trial NCT02641691?
The interventions under investigation include: Fluorouracil (DRUG), Leucovorin (DRUG), Oxaliplatin (DRUG), Radiation (RADIATION).
Who is sponsoring clinical trial NCT02641691?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02641691 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Rectal Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02641691's enrollment target sits among peer trials
20 60th of 70 higher than 6 of 70 other Rectal Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Rectal Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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