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Alzheimer Disease, Early Onset: early-phase trial registry
5 of 12 indexed Alzheimer Disease, Early Onset trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,429 of 28,707 conditions by registered trial count.
12 US clinical trials · 5 currently recruiting · #1,429 of 28,707 conditions by registered trial count
Alzheimer Disease, Early Onset: 12 US clinical trials tracked, 5 recruiting.
Alzheimer Disease, Early Onset is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Pain Therapeutics, running 1 of these trials.
Enrollment posture brief
Registry condition alzheimer-disease-early-onset
OPEN 5 | RECR 42% | LATE 0 | EARLY 5 | RANK #1429 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Adiposity (42% recruiting · 12 trials)
Alzheimer Disease, Early Onset lists 5 open slots (42% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Alzheimer Disease, Early Onset on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Alzheimer Disease, Early Onset is recruiting below its size-band peers.
5 of 12 indexed trials (41.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Alzheimer Disease, Early Onset trials is spread across many organizations.
Pain Therapeutics accounts for 1 of 12 trials (8.3%). 12 distinct sponsors appear on at least one study for this condition label.
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Typical Alzheimer Disease, Early Onset enrolment sits around 90 participants.
Median target enrolment is 90 among the 12 trials that report a genuine target (sentinel values excluded). 7 of those (58.3%) plan for fewer than 100 participants.
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Alzheimer Disease, Early Onset research is mostly interventional.
10 interventional and 2 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
12 total, page 1 of 1
NYSCF Scientific Discovery Biobank
New York Stem Cell Foundation Research Institute
NCT06203106
Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease
Johns Hopkins University
NCT04122001
Lifestyle Interventions for the Treatment of Early Onset Alzheimer's Disease Study
Indiana University
NCT05573490
Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy
Massachusetts Institute of Technology
NCT05655195
Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD
Butler Hospital
NCT04500847
A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (Hope Study, CA-0011)
Cognito Therapeutics
NCT05637801
Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Participants With Early Alzheimer's Disease
Bristol-Myers Squibb
NCT06268886
PMN310 in Patients With Early Alzheimer's Disease (PRECISE-AD)
ProMis Neurosciences
NCT06750432
Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study
Mayo Clinic
NCT02740634
Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD) Study
Washington University School of Medicine
NCT04685590
Genetic Studies in Familial Dementia
University of Miami
NCT04680013
A Safety Study of PTI-125 in Healthy Volunteers
Pain Therapeutics
NCT03784300
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Alzheimer Disease, Early Onset records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Alzheimer Disease, Early Onset trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Alzheimer Disease, Early Onset page
12 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 5 Alzheimer Disease, Early Onset trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Pain Therapeutics sponsors the most Alzheimer Disease, Early Onset trials on record, review their full trial history before evaluating a specific study. See Pain Therapeutics's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Alzheimer Disease, Early Onset condition card totals 12 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.