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Alzheimer Disease, Early Onset clinical trials
5 of 12 indexed Alzheimer Disease, Early Onset trials are currently recruiting.
12 US clinical trials · 5 currently recruiting
Alzheimer Disease, Early Onset is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Pain Therapeutics, running 1 of these trials.
The research picture
Alzheimer Disease, Early Onset has 12 registered US clinical trials, 5 of them open to new participants right now, about 42% of the total.
- 5
- recruiting participants now
- 42%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 1
- top sponsor: Pain Therapeutics
Active & Recent Trials
12 total, page 1 of 1
NYSCF Scientific Discovery Biobank
New York Stem Cell Foundation Research Institute
NCT06203106
Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease
Johns Hopkins University
NCT04122001
Lifestyle Interventions for the Treatment of Early Onset Alzheimer's Disease Study
Indiana University
NCT05573490
Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy
Massachusetts Institute of Technology
NCT05655195
Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD
Butler Hospital
NCT04500847
A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (Hope Study, CA-0011)
Cognito Therapeutics
NCT05637801
Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Participants With Early Alzheimer's Disease
Bristol-Myers Squibb
NCT06268886
PMN310 in Patients With Early Alzheimer's Disease (PRECISE-AD)
ProMis Neurosciences
NCT06750432
Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study
Mayo Clinic
NCT02740634
Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD) Study
Washington University School of Medicine
NCT04685590
Genetic Studies in Familial Dementia
University of Miami
NCT04680013
A Safety Study of PTI-125 in Healthy Volunteers
Pain Therapeutics
NCT03784300
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Alzheimer Disease, Early Onset Trial Landscape
12 indexed Alzheimer Disease, Early Onset studies · 5 recruiting (42%).
Phase mix: 0 late (III/IV) vs 5 early (I/II).
Top sponsor: Pain Therapeutics (1 trial), 9 others listed. 12 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Alzheimer Disease, Early Onset?
PlainTrial tracks 12 US clinical trials for Alzheimer Disease, Early Onset, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Alzheimer Disease, Early Onset?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.