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NCT01274481 · ClinicalTrials.gov registry record · Phase 1
Iloprost Effects on Gas Exchange and Pulmonary Mechanics
A Phase 1 study of Pulmonary Hypertension and Acute Respiratory Distress Syndrome, sponsored by University of Oklahoma.
- Completed
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT01274481: Completed Phase 1 study of Pulmonary Hypertension and Acute Respiratory Distress Syndrome, sponsored by University of Oklahoma.
NCT01274481 is a Phase 1 study of Pulmonary Hypertension and Acute Respiratory Distress Syndrome that has completed, run by University of Oklahoma. The registered enrollment target is 20 participants, below the 613-participant average among 72 other Pulmonary Hypertension trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01274481, a Phase 1 study of Pulmonary Hypertension and Acute Respiratory Distress Syndrome, has completed, sponsored by University of Oklahoma.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will examine the hypothesis that iloprost maintains and improves ventilation perfusion matching in patients with pulmonary hypertension and ARDS/ALI as reflected by 1) an improved PaO2/FIO2 ratio as calculated from the measured arterial blood gases obtained before and after iloprost administration, 2) an improvement in lung compliance, and 3) an improvement in the ventilatory equivalents for oxygen and CO2 measured by expired gas analysis.
Conditions Studied
Interventions
- DRUG Iloprost
Study Locations (1)
Oklahoma
- OU Medical Center - Oklahoma City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2011-03 |
| Est. Completion | 2012-07 |
| Phase | Phase 1 |
What the finished NCT01274481 record still lists
NCT01274481 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 613-participant average among 72 other Pulmonary Hypertension trials with a reported enrollment target (97% lower).
The record links to 3 conditions, with Pulmonary Hypertension appearing as the primary indexed condition, and to 1 intervention - of which Iloprost is the first listed.
NCT01274481 reports a single indexed study location in Oklahoma.
Frequently Asked Questions
What is clinical trial NCT01274481 about?
NCT01274481 is a clinical study titled "Iloprost Effects on Gas Exchange and Pulmonary Mechanics". This study will examine the hypothesis that iloprost maintains and improves ventilation perfusion matching in patients with pulmonary hypertension and ARDS/ALI as reflected by 1) an improved PaO2/FIO2 ratio as calculated from the measured arterial blood gases obtained before and after iloprost admin...
What is the current status of trial NCT01274481?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2011-03. Estimated completion is 2012-07.
What conditions does trial NCT01274481 study?
This clinical trial studies the following conditions: Pulmonary Hypertension, Acute Respiratory Distress Syndrome, Acute Lung Injury.
What interventions are being tested in trial NCT01274481?
The interventions under investigation include: Iloprost (DRUG).
Who is sponsoring clinical trial NCT01274481?
This trial is sponsored by University of Oklahoma, which has 358 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01274481 being conducted?
This trial has 1 study location across Oklahoma. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01274481's enrollment target sits among peer trials
20 58th of 72 higher than 11 of 72 other Pulmonary Hypertension trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pulmonary Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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