Debiopharm International

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Debiopharm International sits in the top decile of US sponsors by registered trial count (#538 of 15,742 sponsors by registered trial count).

30 total trials 5 currently recruiting 16 completed early-phase tilt top decile by trial count

Debiopharm International: 30 sponsored US clinical trials, 5 recruiting.

Debiopharm International sponsors 30 registered US clinical trials on ClinicalTrials.gov, 5 of them currently recruiting, and 16 completed. 7 of these trials are in Phase 3-4 (later-stage) and 23 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hepatitis C, with 2 trials.

Top-decile sponsor footprint

Debiopharm International ranks in the top decile of sponsors by registered trial count (#538 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 21/100

16 of 22 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (72.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

30 total, page 1 of 1

RECRUITING Phase 3

A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs

NCT06930625

RECRUITING Phase 1

A Study to Assess the Safety, Tolerability, and Antileukemic Activity of Debio 1562M in Participants With Acute Myeloid Leukemia (AML)

NCT06969430

RECRUITING Phase 2

A Dose Finding Study of Debio 4228 in Participants With Advanced Prostate Cancer

NCT06395753

RECRUITING Phase 1

A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

NCT05765812

RECRUITING Phase 1

Study of Lunresertib Alone or in Combination With RP-3500 or Debio 0123 in Patients With Advanced Solid Tumors

NCT04855656

ACTIVE NOT RECRUITING Phase 3

A Study to Assess the Efficacy, Safety, and Pharmacokinetics of Debio 4326 in Pediatric Participants With Central Precocious Puberty (LIBELULA™ Clinical Trial)

NCT06129539

ACTIVE NOT RECRUITING Phase 1

Debio 0123 in Combination With Carboplatin and Etoposide in Adult Participants With Small Cell Lung Cancer That Recurred or Progressed After Previous Standard Platinum-Based Therapy

NCT05815160

ACTIVE NOT RECRUITING Phase 1

A Study to Evaluate Safety and Preliminary Anti-tumor Activity of Debio 0123 as Monotherapy in Adult Participants With Advanced Solid Tumors

NCT05109975

TERMINATED Phase 1

Study of RP-6306 With FOLFIRI in Advanced Solid Tumors

NCT05147350

TERMINATED Phase 1

Study of RP-6306 With Gemcitabine in Advanced Solid Tumors

NCT05147272

COMPLETED Phase 1

Study to Assess Safety and Efficacy of the Second Mitochondrial-derived Activator of Caspases (SMAC) Mimetic Debio 1143

NCT04122625

TERMINATED Phase 2

Basket Trial in Solid Tumors Harboring a Fusion of FGFR1, FGFR2 or FGFR3- (FUZE Clinical Trial)

NCT03834220

COMPLETED Phase 2

Study to Evaluate the Efficacy and Tolerability of Debio 1562 in Combination With Rituximab in Participants With Relapsed and/or Refractory DLBCL and Other Forms of NHL

NCT02564744

COMPLETED Phase 1

Drug Penetration Into Bone After Repeated Oral Administration of Debio 1450 to Patients Undergoing Hip Replacement Surgery

NCT02726438

COMPLETED Phase 2

Study of Debio 1450 for Bacterial Skin Infections

NCT02426918

COMPLETED Phase 1

A Multiple Dose Study of Debio 1450 [Intravenous (IV) and Oral] in Healthy Volunteers

NCT02214433

COMPLETED Phase 1

A Single Dose Study of Debio 1450 in Healthy Subjects

NCT02162199

COMPLETED Phase 2

Alisporivir With RBV in Chronic Hepatitis C Genotype 2 and 3 Participants for Whom Interferon is Not an Option

NCT02094443

COMPLETED Phase 1

Pharmacokinetics and Safety of Alisporivir in Subjects With End Stage Renal Disease on Hemodialysis Compared to Healthy Subjects

NCT01975337

TERMINATED Phase 1

Debio 1347-101 Phase I Trial in Advanced Solid Tumours With Fibroblast Growth Factor Receptor (FGFR) Alterations

NCT01948297

COMPLETED Phase 3

Efficacy, Safety, and Pharmacokinetics (PK) of Triptorelin 6-month Formulation in Patients With Central Precocious Puberty

NCT01467882

TERMINATED Phase 3

Alisporivir With PEG and RBV in Protease Inhibitor (PI) Treatment Failure Patients With Chronic Hepatitis C

NCT01500772

COMPLETED Phase 3

Long Term Follow-up Study to Assess Durability of Sustained Virologic Response in Alisporivir-treated Hepatitis C Patients

NCT02753699

TERMINATED Phase 3

Alisporivir (Deb025) and Boceprevir Triple Therapies in African American Participants Not Previously Treated for Chronic Hepatitis C Genotype 1

NCT01446250

COMPLETED Phase 1

Evaluate the Pharmacokinetics, Safety, and Tolerability of Alisporivir in Subjects With Hepatic Impairment Compared to Healthy Subjects

NCT01860326

COMPLETED Phase 3

Efficacy and Safety of Alisporivir Triple Therapy in Chronic Hepatitis C Genotype 1 Treatment-naïve Participants

NCT01318694

COMPLETED Phase 2

Efficacy and Safety of Alisporivir Alone or Combined With RBV or PEG in Chronic Hepatitis C Genotype 2 and 3 Treatment-naïve Participants

NCT01215643

COMPLETED Phase 2

Efficacy and Safety of Adding Alisporivir (DEB025) to Peginterferon (IFN) Alfa-2a (Peg-IFN Alfa-2a) and Ribavirin in Chronic HCV Genotype 1 Patients Who Relapsed or Did Not Respond to Previous Treatment

NCT01183169

COMPLETED Phase 1

Dose Escalation Study of Safety and Tolerability of AT-406 in Patients With Advanced Solid Tumors and Lymphomas

NCT01078649

COMPLETED Phase 2

A Study of Debio 025 in Combination With PegIFN Alpha-2a and Ribavirin in Chronic HCV Patients Non-responders to Standard Treatment

NCT00537407

What is open in the Debiopharm International pipeline

5 recruiting of 30 indexed (17% open); 16 completed (53%).

Phase mix: 7 late (III/IV) vs 23 early (I/II) (early-phase heavy).

Top condition: Hepatitis C (2 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Debiopharm International: open-pipeline peers nationwide

Peers matched on 30 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Debiopharm International sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 010203040 0%5%10%15%20% Total trials Recruiting share Debiopharm InternationalBiotronikCharles Drew University of Medicine and ScienceChiesi Farmaceutici S.p.A.Exact Sciences CorporationAdageneAgendiaAkamis BioAngiodynamics
Debiopharm International sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Debiopharm International sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 30 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Debiopharm International page

30 registered trials is a research-attention snapshot, not an endorsement of Debiopharm International or any single study.

  • 5 of Debiopharm International's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Hepatitis C is the condition Debiopharm International studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Hepatitis C trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Debiopharm International pipeline card: 30 registered trials from official public datasets.Report a data error.