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NCT04837040 · ClinicalTrials.gov registry record · Phase 3

A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly

A Phase 3 study of Acromegaly, sponsored by Crinetics Pharmaceuticals.

Active
Registry status
Phase 3
Development phase
58
Enrollment target
20
Study locations

NCT04837040 is a Phase 3 study of Acromegaly that is active but no longer recruiting, run by Crinetics Pharmaceuticals. The registered enrollment target is 58 participants, below the 97-participant average among 13 other Acromegaly trials with a reported enrollment target (40% lower). The trial reports 20 study locations across 10 states.

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The verdict

NCT04837040, a Phase 3 study of Acromegaly, is active but no longer recruiting, sponsored by Crinetics Pharmaceuticals.

ACTIVE NOT RECRUITING
Registry status
Phase 3
Development phase
58 participants
Enrollment target
20
Study locations

Study Summary

A randomized, placebo-controlled study designed to evaluate the safety and efficacy of paltusotine (also known as CRN00808; an orally administered nonpeptide somatostatin agonist) in subjects with acromegaly previously treated with somatostatin receptor ligand (SRL) based treatment regimens.

Conditions Studied

Acromegaly

Interventions

  • DRUG Placebo
  • DRUG Paltusotine

Study Locations (20)

Other

  • Crinetics Study Site - Córdoba
  • Crinetics Study Site - Ghent
  • Crinetics Study Site - Rio de Janeiro
  • Crinetics Study Site - Rio de Janeiro
  • Crinetics Study Site - Sofia
  • Crinetics Study Site - Bron
  • Crinetics Study Site - Pessac
  • Crinetics Study Site - Budapest

California

  • Crinetics Study Site - Los Angeles
  • Crinetics Study Site - Torrance

Pennsylvania

  • Crinetics Study Site - Philadelphia
  • Crinetics Study Site - Pittsburgh

Buenos Aires

  • Crinetics Study Site - CABA
  • Crinetics Study Site - Ciudad Autonoma de Buenos Aire

Maryland

  • Crinetics Study Site - Baltimore

Massachusetts

  • Crinetics Study Site - Boston

Tennessee

  • Crinetics Study Site - Nashville

Ceará

  • Crinetics Study Site - Fortaleza

Trial Details

FieldValue
Enrollment Target 58 participants
Start Date 2021-05-12
Est. Completion 2027-06
Phase Phase 3

Sponsor

Crinetics Pharmaceuticals

16 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04837040

The ClinicalTrials.gov registry entry for NCT04837040 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 58 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 97-participant average among 13 other Acromegaly trials with a reported enrollment target (40% lower). The listed sponsor is Crinetics Pharmaceuticals, which has 16 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Acromegaly appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT04837040 reports 20 study locations spanning 10 distinct geographic areas - top geographies include Other, California, Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT04837040 about?

NCT04837040 is a clinical study titled "A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly". A randomized, placebo-controlled study designed to evaluate the safety and efficacy of paltusotine (also known as CRN00808; an orally administered nonpeptide somatostatin agonist) in subjects with acromegaly previously treated with somatostatin receptor ligand (SRL) based treatment regimens.

What is the current status of trial NCT04837040?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 58 participants. The study started on 2021-05-12. Estimated completion is 2027-06.

What conditions does trial NCT04837040 study?

This clinical trial studies the following conditions: Acromegaly.

What interventions are being tested in trial NCT04837040?

The interventions under investigation include: Placebo (DRUG), Paltusotine (DRUG).

Who is sponsoring clinical trial NCT04837040?

This trial is sponsored by Crinetics Pharmaceuticals, which has 16 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04837040 being conducted?

This trial has 20 study locations across California, Maryland, Massachusetts, Pennsylvania, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.