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NCT07281937 · ClinicalTrials.gov registry record · Phase 2
A Study of Weekly Oral Ecnoglutide (VRB-101) in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
A Phase 2 study of Obesity and Overweight, sponsored by Verdiva Bio Dev Limited.
- Active
- Registry status
- Phase 2
- Development phase
- 206
- Enrollment target
- 20
- Study locations
NCT07281937: Active Phase 2 study of Obesity and Overweight, sponsored by Verdiva Bio Dev Limited.
NCT07281937 is a Phase 2 study of Obesity and Overweight that is active but no longer recruiting, run by Verdiva Bio Dev Limited. The registered enrollment target is 206 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (75% lower). The trial reports 20 study locations across 15 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07281937, a Phase 2 study of Obesity and Overweight, is active but no longer recruiting, sponsored by Verdiva Bio Dev Limited.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 206 participants
- Enrollment target
- 20
- Study locations
Study Summary
The aim of this study is to evaluate the efficacy of VRB-101 for body weight reduction compared to placebo in participants who have obesity or overweight with weight-related comorbidities.
Primary Outcome
To evaluate the efficacy of VRB-101 for body weight reduction compared to placebo in Schedule A dose regimens.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG VRB-101
Study Locations (20)
California
- Clinical Study Site 111 - Anaheim
- Clinical Study Site 107 - Montclair
- Clinical Study Site 118 - Tarzana
Alabama
- Clinical Study Site 103 - Anniston
- Clinical Study Site 109 - Cullman
New York
- Clinical Study Site 117 - Binghamton
- Clinical Study Site 101 - Rochester
North Carolina
- Clinical Study Site 120 - Charlotte
- Clinical Study Site 108 - Monroe
Arizona
- Clinical Study Site 110 - Phoenix
Arkansas
- Clinical Study Site 113 - Little Rock
Georgia
- Clinical Study Site 119 - Decatur
Iowa
- Clinical Study Site 116 - West Des Moines
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 206 participants |
| Start Date | 2025-11-25 |
| Est. Completion | 2026-08 |
| Phase | Phase 2 |
What the registry record for NCT07281937 still lists
NCT07281937 is an interventional study that assigns participants to a tested intervention. The registered 206 participants enrollment target is mid-sized for trials with a published cap, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (75% lower).
The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07281937 names 20 study sites across 15 states, led by California, Alabama, New York.
Frequently Asked Questions
What is clinical trial NCT07281937 about?
NCT07281937 is a clinical study titled "A Study of Weekly Oral Ecnoglutide (VRB-101) in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities". The aim of this study is to evaluate the efficacy of VRB-101 for body weight reduction compared to placebo in participants who have obesity or overweight with weight-related comorbidities.
What is the current status of trial NCT07281937?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 206 participants. The study started on 2025-11-25. Estimated completion is 2026-08.
What conditions does trial NCT07281937 study?
This clinical trial studies the following conditions: Obesity, Overweight.
What interventions are being tested in trial NCT07281937?
The interventions under investigation include: Placebo (DRUG), VRB-101 (DRUG).
Who is sponsoring clinical trial NCT07281937?
This trial is sponsored by Verdiva Bio Dev Limited, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07281937 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07281937's enrollment target sits among peer trials
206 309th of 1053 higher than 745 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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