Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03373968 · ClinicalTrials.gov registry record · Phase 2

Givinostat in Duchenne's Muscular Dystrophy Long-term Safety and Tolerability Study

A Phase 2 study of Duchenne Muscular Dystrophy, sponsored by Italfarma.

Recruiting
Registry status
Phase 2
Development phase
206
Enrollment target
20
Study locations

NCT03373968 is a Phase 2 study of Duchenne Muscular Dystrophy that is actively recruiting participants, run by Italfarma. The registered enrollment target is 206 participants, below the 408-participant average among 48 other Duchenne Muscular Dystrophy trials with a reported enrollment target (50% lower). The trial reports 20 study locations across 13 states.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03373968, a Phase 2 study of Duchenne Muscular Dystrophy, is actively recruiting participants, sponsored by Italfarma.

RECRUITING
Registry status
Phase 2
Development phase
206 participants
Enrollment target
20
Study locations

Study Summary

This is an open label, long-term safety, tolerability, and efficacy study of GIVINOSTAT in all DMD (Duchenne's muscular dystrophy) patients who have been previously treated in one of the GIVINOSTAT studies.

Interventions

  • DRUG Givinostat

Study Locations (20)

Other

  • University Hospitals Leuven, Neuromuscular Reference Centre, Child Neurology - Leuven
  • Hospital de La Citadelle, Centre de Référence des Maladies Neuromuscolaires (CRMN) - Liège
  • CHU de Nantes - Hotel-Dieu - Hopital Nord Laennec, rez-de-chausse haut ail Ouest - Nantes
  • Hôpital Armand Trousseau I-Motion - Plateforme d'essais cliniques pédiatriques Bâtiment Lemariey - Porte 20 * 2ème étage 26 Avenue du Dr Arnold Nette - Paris
  • Universitätsklinikum Essen - Kinder-und Jugendmedizin Neuropadiatrie - Essen
  • Klinik- und Poliklinik fur Kinder- und Jugendmedizin, Universitatsklinikum HamburgEppendorf, Martinistr. 52 - Hamburg
  • Klinikum der Universitat Munchen, Campus Innenstadt, Lindwurmstr. 4 - München

California

  • University of California - Davis Medical Center - Devis Physical Medicine & Rehabilitation - Sacramento
  • Rady Children's Hospital center - UCSD Department of Neuroscience - San Diego

Connecticut

  • Connecticut Children's Medical Center, Neurology Division - Hartford

Florida

  • Child Health Research Institute - Gainesville

Georgia

  • MD Rare Disease Research, LLC - Atlanta

Iowa

  • University of Iowa Children's Hospital - Iowa City

Missouri

  • Washington University School of Medicine in St Louis Department of Neurology 660 S.Euclid Avenue, Campus Box 8111 - St Louis

Oregon

  • Shriners Hospitals for Children - Portland

Trial Details

FieldValue
Enrollment Target 206 participants
Start Date 2017-10-24
Est. Completion 2029-12
Phase Phase 2

Sponsor

Italfarma

2 total trials

What the Registry Record Tells You About NCT03373968

The ClinicalTrials.gov registry entry for NCT03373968 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 206 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 408-participant average among 48 other Duchenne Muscular Dystrophy trials with a reported enrollment target (50% lower). The listed sponsor is Italfarma, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Duchenne Muscular Dystrophy appearing as the primary indexed condition, and to 1 intervention - of which Givinostat is the first listed.

NCT03373968 reports 20 study locations spanning 13 distinct geographic areas - top geographies include Other, California, Connecticut.

Frequently Asked Questions

What is clinical trial NCT03373968 about?

NCT03373968 is a clinical study titled "Givinostat in Duchenne's Muscular Dystrophy Long-term Safety and Tolerability Study". This is an open label, long-term safety, tolerability, and efficacy study of GIVINOSTAT in all DMD (Duchenne's muscular dystrophy) patients who have been previously treated in one of the GIVINOSTAT studies.

What is the current status of trial NCT03373968?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 206 participants. The study started on 2017-10-24. Estimated completion is 2029-12.

What conditions does trial NCT03373968 study?

This clinical trial studies the following conditions: Duchenne Muscular Dystrophy.

What interventions are being tested in trial NCT03373968?

The interventions under investigation include: Givinostat (DRUG).

Who is sponsoring clinical trial NCT03373968?

This trial is sponsored by Italfarma, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03373968 being conducted?

This trial has 20 study locations across California, Connecticut, Florida, Georgia, Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Duchenne Muscular Dystrophy

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.