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NCT07227792 · ClinicalTrials.gov registry record · NA
Tongue-out Radiation Therapy (TORT) for the Mitigation of Radiotherapy-related Toxicities in Patients With Head and Neck Cancer
A NA study of Head and Neck Carcinoma, sponsored by Yvonne Mowery.
- Recruiting
- Registry status
- NA
- Development phase
- 35
- Enrollment target
- 1
- Study location
NCT07227792: Recruiting NA study of Head and Neck Carcinoma, sponsored by Yvonne Mowery.
NCT07227792 is a NA study of Head and Neck Carcinoma that is actively recruiting participants, run by Yvonne Mowery. The registered enrollment target is 35 participants, below the 412-participant average among 30 other Head and Neck Carcinoma trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07227792, a NA study of Head and Neck Carcinoma, is actively recruiting participants, sponsored by Yvonne Mowery.
- RECRUITING
- Registry status
- NA
- Development phase
- 35 participants
- Enrollment target
- 1
- Study location
Study Summary
Our institution recently began incorporating a novel "tongue-out" radiation therapy (TORT) technique for patients with head and neck tumors at particular subsites (oropharynx, larynx, hypopharynx). Protruding the tongue, i.e. "tongue-out" position, induces anatomical changes that facilitate decreased radiation dose to the oral tongue and PCM. The long-term goal is to determine whether TORT results in reduced severity and faster recovery from acute treatment-related toxicities (particularly mucositis, dysphagia, and dysgeusia) and improved long-term swallowing function and taste compared to traditional "tongue-in" RT for patients with HNC.
Primary Outcome
Mean difference in Eating Assessment Tool 10 (EAT-10) total scores between patients enrolled on this prospective study and matched retrospective controls. EAT-10 screens for dysphagia and aspiration risk. Total score ranges 0 - 40. Patients rate each question on a scale of 0 (no problem) to 4 (severe problem) regarding, weight loss, inability to go out for meals, increased swallowing effort, pain while swallowing, reduced pleasure while eating, bolus sensation, coughing, and stress when swallowi
Conditions Studied
Interventions
- RADIATION Tongue-out radiation therapy (TORT)
Study Locations (1)
Pennsylvania
- UPMC Hillman Cancer Center - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2025-11-23 |
| Est. Completion | 2029-01-31 |
| Phase | NA |
What NCT07227792 shows while recruiting
NCT07227792 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 35 participants, a relatively small participant target, below the 412-participant average among 30 other Head and Neck Carcinoma trials with a reported enrollment target (92% lower).
The record links to 1 condition, with Head and Neck Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which Tongue-out radiation therapy (TORT) is the first listed.
NCT07227792 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT07227792 about?
NCT07227792 is a clinical study titled "Tongue-out Radiation Therapy (TORT) for the Mitigation of Radiotherapy-related Toxicities in Patients With Head and Neck Cancer". Our institution recently began incorporating a novel "tongue-out" radiation therapy (TORT) technique for patients with head and neck tumors at particular subsites (oropharynx, larynx, hypopharynx). Protruding the tongue, i.e. "tongue-out" position, induces anatomical changes that facilitate decrease...
What is the current status of trial NCT07227792?
This trial is currently recruiting. It is a NA study. The enrollment target is 35 participants. The study started on 2025-11-23. Estimated completion is 2029-01-31.
What conditions does trial NCT07227792 study?
This clinical trial studies the following conditions: Head and Neck Carcinoma.
What interventions are being tested in trial NCT07227792?
The interventions under investigation include: Tongue-out radiation therapy (TORT) (RADIATION).
Who is sponsoring clinical trial NCT07227792?
This trial is sponsored by Yvonne Mowery, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07227792 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07227792's enrollment target sits among peer trials
35 19th of 30 higher than 11 of 30 other Head and Neck Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Head and Neck Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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