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NCT07227792 · ClinicalTrials.gov registry record · NA

Tongue-out Radiation Therapy (TORT) for the Mitigation of Radiotherapy-related Toxicities in Patients With Head and Neck Cancer

A NA study of Head and Neck Carcinoma, sponsored by Yvonne Mowery.

Recruiting
Registry status
NA
Development phase
35
Enrollment target
1
Study location

NCT07227792 is a NA study of Head and Neck Carcinoma that is actively recruiting participants, run by Yvonne Mowery. The registered enrollment target is 35 participants, below the 412-participant average among 30 other Head and Neck Carcinoma trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07227792, a NA study of Head and Neck Carcinoma, is actively recruiting participants, sponsored by Yvonne Mowery.

RECRUITING
Registry status
NA
Development phase
35 participants
Enrollment target
1
Study location

Study Summary

Our institution recently began incorporating a novel "tongue-out" radiation therapy (TORT) technique for patients with head and neck tumors at particular subsites (oropharynx, larynx, hypopharynx). Protruding the tongue, i.e. "tongue-out" position, induces anatomical changes that facilitate decreased radiation dose to the oral tongue and PCM. The long-term goal is to determine whether TORT results in reduced severity and faster recovery from acute treatment-related toxicities (particularly mucositis, dysphagia, and dysgeusia) and improved long-term swallowing function and taste compared to traditional "tongue-in" RT for patients with HNC.

Conditions Studied

Interventions

  • RADIATION Tongue-out radiation therapy (TORT)

Study Locations (1)

Pennsylvania

  • UPMC Hillman Cancer Center - Pittsburgh

Trial Details

FieldValue
Enrollment Target 35 participants
Start Date 2025-11-23
Est. Completion 2029-01-31
Phase NA

Sponsor

Yvonne Mowery

1 total trials

What the Registry Record Tells You About NCT07227792

The ClinicalTrials.gov registry entry for NCT07227792 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 35 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 412-participant average among 30 other Head and Neck Carcinoma trials with a reported enrollment target (92% lower). The listed sponsor is Yvonne Mowery, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Head and Neck Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which Tongue-out radiation therapy (TORT) is the first listed.

NCT07227792 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT07227792 about?

NCT07227792 is a clinical study titled "Tongue-out Radiation Therapy (TORT) for the Mitigation of Radiotherapy-related Toxicities in Patients With Head and Neck Cancer". Our institution recently began incorporating a novel "tongue-out" radiation therapy (TORT) technique for patients with head and neck tumors at particular subsites (oropharynx, larynx, hypopharynx). Protruding the tongue, i.e. "tongue-out" position, induces anatomical changes that facilitate decrease...

What is the current status of trial NCT07227792?

This trial is currently recruiting. It is a NA study. The enrollment target is 35 participants. The study started on 2025-11-23. Estimated completion is 2029-01-31.

What conditions does trial NCT07227792 study?

This clinical trial studies the following conditions: Head and Neck Carcinoma.

What interventions are being tested in trial NCT07227792?

The interventions under investigation include: Tongue-out radiation therapy (TORT) (RADIATION).

Who is sponsoring clinical trial NCT07227792?

This trial is sponsored by Yvonne Mowery, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07227792 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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