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NCT06985784 · ClinicalTrials.gov registry record · NA

Virtual Reality Interventions for the Improvement of Depression, Anxiety and Pain in Patients With Head and Neck Cancer and Caregivers

A NA study of Head and Neck Carcinoma, sponsored by City of Hope Medical Center.

Recruiting
Registry status
NA
Development phase
40
Enrollment target
1
Study location

NCT06985784: Recruiting NA study of Head and Neck Carcinoma, sponsored by City of Hope Medical Center.

NCT06985784 is a NA study of Head and Neck Carcinoma that is actively recruiting participants, run by City of Hope Medical Center. The registered enrollment target is 40 participants, below the 412-participant average among 30 other Head and Neck Carcinoma trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06985784, a NA study of Head and Neck Carcinoma, is actively recruiting participants, sponsored by City of Hope Medical Center.

RECRUITING
Registry status
NA
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

This clinical trial tests how well a three-dimensional (3D) mindfulness virtual reality (VR) versus (vs) two-dimensional (2D) non-immersive interventions works in improving depression, anxiety, pain, and/or stress in patients with head and neck cancer (HNC) undergoing radiation or chemoradiation (C/RT), and their caregivers. HNC patients undergoing C/RT can experience higher levels of depression, anxiety, distress and pain that negatively impact their quality of life. VR allows for a realistic experience and works as an effective distraction tool from the state of pain or anxiety without use of drugs and with minimal associated risk to patients. VR has been shown to help reduce symptoms of depression, anxiety and pain in non-cancer patients, however there is limited evidence of how well VR use works in cancer patients, especially in patients undergoing C/RT for HNC. Caregivers of these patients also experience high levels of anxiety and distress. Using VR interventions may improve depression, anxiety, pain and/or stress in patients with HNC undergoing C/RT and their caregivers.

Primary Outcome

Will be considered feasible if ≥ 50% of patients agree to participate. Will be assessed using summary statistics.

Conditions Studied

Interventions

  • OTHER Questionnaire Administration
  • OTHER Medical Device Usage and Evaluation
  • OTHER Interview
  • OTHER Virtual Technology Intervention

Study Locations (1)

California

  • City of Hope Medical Center - Duarte

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2025-06-25
Est. Completion 2027-11-09
Phase NA
City of Hope Medical Center

582 total trials

What NCT06985784 shows while recruiting

NCT06985784 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 412-participant average among 30 other Head and Neck Carcinoma trials with a reported enrollment target (90% lower).

The record links to 1 condition, with Head and Neck Carcinoma appearing as the primary indexed condition, and to 4 interventions - of which Questionnaire Administration is the first listed.

NCT06985784 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT06985784 about?

NCT06985784 is a clinical study titled "Virtual Reality Interventions for the Improvement of Depression, Anxiety and Pain in Patients With Head and Neck Cancer and Caregivers". This clinical trial tests how well a three-dimensional (3D) mindfulness virtual reality (VR) versus (vs) two-dimensional (2D) non-immersive interventions works in improving depression, anxiety, pain, and/or stress in patients with head and neck cancer (HNC) undergoing radiation or chemoradiation (C/...

What is the current status of trial NCT06985784?

This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2025-06-25. Estimated completion is 2027-11-09.

What conditions does trial NCT06985784 study?

This clinical trial studies the following conditions: Head and Neck Carcinoma.

What interventions are being tested in trial NCT06985784?

The interventions under investigation include: Questionnaire Administration (OTHER), Medical Device Usage and Evaluation (OTHER), Interview (OTHER), Virtual Technology Intervention (OTHER).

Who is sponsoring clinical trial NCT06985784?

This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06985784 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Head and Neck Carcinoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06985784's enrollment target sits among peer trials

40 18th of 30 higher than 13 of 30 other Head and Neck Carcinoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Head and Neck Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06985784, the US trial registry maintained by the National Library of Medicine. NCT06985784 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.