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NCT06183268 · ClinicalTrials.gov registry record · NA
Evaluation of Radiobiological Effects in Skin Toxicities Head and Neck Cancer Patients With PBS Proton Therapy
A NA study of Head and Neck Cancer and Head and Neck Squamous Cell Carcinoma, sponsored by Covenant Health Cancer Center.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT06183268: Recruiting NA study of Head and Neck Cancer and Head and Neck Squamous Cell Carcinoma, sponsored by Covenant Health Cancer Center.
NCT06183268 is a NA study of Head and Neck Cancer and Head and Neck Squamous Cell Carcinoma that is actively recruiting participants, run by Covenant Health Cancer Center. The registered enrollment target is 100 participants, below the 260-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (62% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06183268, a NA study of Head and Neck Cancer and Head and Neck Squamous Cell Carcinoma, is actively recruiting participants, sponsored by Covenant Health Cancer Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
This purpose of this study is to examine skin reactions (called radiation dermatitis) that occur during pencil beam scanning (PBS) proton therapy. The researchers will test a unique technique called "Spot Delete" to see if it can reduce skin reactions for head \& neck patients treated with PBS. The investigators will also use a special computer model to study how the energy of the proton beam (linear energy transfer) is related to these skin reactions. The study involves creating a treatment plan based on a CT scan, which helps guide the proton beam in the body.
Primary Outcome
Aim to test the hypothesis that the "Spot Delete" technique in proton therapy reduces radiation dermatitis in head \& neck cancer patients compared to historical data from patients who underwent regular proton therapy without the technique. To evaluate this, the investigators will compare the extent of skin reactions in patients who receive proton therapy with the "Spot Delete" technique to historical data from patients who did not receive this treatment.
Conditions Studied
Interventions
- RADIATION Spot Delete
Study Locations (1)
Tennessee
- Thompson Proton Center - Knoxville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2023-12-13 |
| Est. Completion | 2030-01-02 |
| Phase | NA |
What NCT06183268 shows while recruiting
NCT06183268 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 260-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (62% lower).
The record links to 3 conditions, with Head and Neck Cancer appearing as the primary indexed condition, and to 1 intervention - of which Spot Delete is the first listed.
NCT06183268 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT06183268 about?
NCT06183268 is a clinical study titled "Evaluation of Radiobiological Effects in Skin Toxicities Head and Neck Cancer Patients With PBS Proton Therapy". This purpose of this study is to examine skin reactions (called radiation dermatitis) that occur during pencil beam scanning (PBS) proton therapy. The researchers will test a unique technique called "Spot Delete" to see if it can reduce skin reactions for head \& neck patients treated with PBS. The ...
What is the current status of trial NCT06183268?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2023-12-13. Estimated completion is 2030-01-02.
What conditions does trial NCT06183268 study?
This clinical trial studies the following conditions: Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Head and Neck Carcinoma.
What interventions are being tested in trial NCT06183268?
The interventions under investigation include: Spot Delete (RADIATION).
Who is sponsoring clinical trial NCT06183268?
This trial is sponsored by Covenant Health Cancer Center, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06183268 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06183268's enrollment target sits among peer trials
100 82nd of 250 higher than 165 of 250 other Head and Neck Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Head and Neck Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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