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NCT01697371 · ClinicalTrials.gov registry record · NA
Proton Therapy in the Treatment of Liver Metastases
A NA study of Liver Metastases, sponsored by Loma Linda University.
- Recruiting
- Registry status
- NA
- Development phase
- 35
- Enrollment target
- 1
- Study location
NCT01697371: Recruiting NA study of Liver Metastases, sponsored by Loma Linda University.
NCT01697371 is a NA study of Liver Metastases that is actively recruiting participants, run by Loma Linda University. The registered enrollment target is 35 participants, below the 67-participant average among 27 other Liver Metastases trials with a reported enrollment target (48% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01697371, a NA study of Liver Metastases, is actively recruiting participants, sponsored by Loma Linda University.
- RECRUITING
- Registry status
- NA
- Development phase
- 35 participants
- Enrollment target
- 1
- Study location
Study Summary
Local control of hepatic metastases appears to be a major determinant of overall survival. However, many patients are not suitable for resection due to medical or surgical reasons. Therefore, there is an important role for a treatment that can provide the equivalent of tumor resection with minimal morbidity. Stereotactic body radiotherapy (SBRT) delivers an ablative regimen of highly focused external beam radiotherapy that targets one or more discrete extracranial lesions. Published reports using SBRT to treat liver metastases have shown actuarial local control rates ranging from 50-100% with higher doses associated with better local control. In patients with metastatic liver disease, aggressive local therapy using modern radiotherapy techniques are promising and project to have a substantial role in the treatment of metastatic liver cancer to treat unresectable disease. The dosimetric advantage of proton therapy may lead to improved clinical outcomes with less morbidity, however, there is no clinical data to confirm this assertion. We thus propose a phase I study to determine the feasibility and safety of stereotactic body proton therapy in patients with liver metastases followed by a phase II study to determine the efficacy of such treatment on local control.
Conditions Studied
Interventions
- RADIATION Proton Radiation
- RADIATION Proton
Study Locations (1)
California
- Loma Linda University Medical Center - Loma Linda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2012-08-22 |
| Est. Completion | 2033-09 |
| Phase | NA |
What NCT01697371 shows while recruiting
NCT01697371 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 35 participants, a relatively small participant target, below the 67-participant average among 27 other Liver Metastases trials with a reported enrollment target (48% lower).
The record links to 1 condition, with Liver Metastases appearing as the primary indexed condition, and to 2 interventions - of which Proton Radiation is the first listed.
NCT01697371 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT01697371 about?
NCT01697371 is a clinical study titled "Proton Therapy in the Treatment of Liver Metastases". Local control of hepatic metastases appears to be a major determinant of overall survival. However, many patients are not suitable for resection due to medical or surgical reasons. Therefore, there is an important role for a treatment that can provide the equivalent of tumor resection with minimal m...
What is the current status of trial NCT01697371?
This trial is currently recruiting. It is a NA study. The enrollment target is 35 participants. The study started on 2012-08-22. Estimated completion is 2033-09.
What conditions does trial NCT01697371 study?
This clinical trial studies the following conditions: Liver Metastases.
What interventions are being tested in trial NCT01697371?
The interventions under investigation include: Proton Radiation (RADIATION), Proton (RADIATION).
Who is sponsoring clinical trial NCT01697371?
This trial is sponsored by Loma Linda University, which has 237 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01697371 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Liver Metastases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01697371's enrollment target sits among peer trials
35 13th of 27 higher than 15 of 27 other Liver Metastases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Liver Metastases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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