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NCT07157033 · ClinicalTrials.gov registry record · Phase 1

A Phase 1 Study to Evaluate Safety and Efficacy of XER-001 (Amifostine for Nasoduodenal Delivery) in Combination With Sterotactic Body Radiotherapy for Treatment in Patients With Locally Advanced Pancreatic Cancer.

A Phase 1 study of Locally Advanced Pancreatic Adenocarcinoma and Locally Advanced Pancreatic Ductal Adenocarcinoma, sponsored by Xerient Pharma.

Recruiting
Registry status
Phase 1
Development phase
36
Enrollment target
2
Study locations

NCT07157033 is a Phase 1 study of Locally Advanced Pancreatic Adenocarcinoma and Locally Advanced Pancreatic Ductal Adenocarcinoma that is actively recruiting participants, run by Xerient Pharma. The registered enrollment target is 36 participants, below the 65-participant average among 18 other Locally Advanced Pancreatic Adenocarcinoma trials with a reported enrollment target (45% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT07157033, a Phase 1 study of Locally Advanced Pancreatic Adenocarcinoma and Locally Advanced Pancreatic Ductal Adenocarcinoma, is actively recruiting participants, sponsored by Xerient Pharma.

RECRUITING
Registry status
Phase 1
Development phase
36 participants
Enrollment target
2
Study locations

Study Summary

The purpose of this study is to assess the safety, tolerability and efficacy of XER-001 and identify a best dose for future studies.

Interventions

  • DRUG XER-001

Study Locations (2)

New Mexico

  • Christus St. Vincent Regional Cancer Center - Santa Fe

Texas

  • Oncology Consultants, P.A. - Houston

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2026-01-01
Est. Completion 2034-07-31
Phase Phase 1

Sponsor

Xerient Pharma

1 total trials

What the Registry Record Tells You About NCT07157033

The ClinicalTrials.gov registry entry for NCT07157033 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 65-participant average among 18 other Locally Advanced Pancreatic Adenocarcinoma trials with a reported enrollment target (45% lower). The listed sponsor is Xerient Pharma, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Locally Advanced Pancreatic Adenocarcinoma appearing as the primary indexed condition, and to 1 intervention - of which XER-001 is the first listed.

NCT07157033 reports 2 study locations spanning 2 distinct geographic areas - top geographies include New Mexico, Texas.

Frequently Asked Questions

What is clinical trial NCT07157033 about?

NCT07157033 is a clinical study titled "A Phase 1 Study to Evaluate Safety and Efficacy of XER-001 (Amifostine for Nasoduodenal Delivery) in Combination With Sterotactic Body Radiotherapy for Treatment in Patients With Locally Advanced Pancreatic Cancer.". The purpose of this study is to assess the safety, tolerability and efficacy of XER-001 and identify a best dose for future studies.

What is the current status of trial NCT07157033?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2026-01-01. Estimated completion is 2034-07-31.

What conditions does trial NCT07157033 study?

This clinical trial studies the following conditions: Locally Advanced Pancreatic Adenocarcinoma, Locally Advanced Pancreatic Ductal Adenocarcinoma, Locally Advanced Pancreas Cancer.

What interventions are being tested in trial NCT07157033?

The interventions under investigation include: XER-001 (DRUG).

Who is sponsoring clinical trial NCT07157033?

This trial is sponsored by Xerient Pharma, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07157033 being conducted?

This trial has 2 study locations across New Mexico, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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