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RECRUITING Phase 1

PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC)

NCT06673017 · View on ClinicalTrials.gov ↗

Study Summary

This is a multi-center, non-randomized, single-arm, open-label, phase Ib, dose escalation/dose expansion study of PTM-101 when combined with neoadjuvant chemotherapy for the treatment of treatment-naïve subjects with borderline resectable and locally advanced pancreatic ductal adenocarcinoma (PDAC).

Interventions

  • DRUG PTM-101

Study Locations (6)

Texas

  • University of Texas Southwestern Medical Center — Dallas
  • The University of Texas MD Anderson Cancer Center — Houston

California

  • Hoag Memorial Hospital Presbyterian — Newport Beach

Michigan

  • Karmanos Cancer Institute — Detroit

New York

  • Northwell Health Zuckerberg Cancer Center — Lake Success

Washington

  • Virginia Mason Medical Center — Seattle

Trial Details

FieldValue
Enrollment Target 26 participants
Start Date 2025-04-14
Est. Completion 2028-06
Phase Phase 1

Sponsor

PanTher Therapeutics

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06673017

The ClinicalTrials.gov registry entry for NCT06673017 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 26 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is PanTher Therapeutics, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with Pancreatic Cancer appearing as the primary indexed condition, and to 1 intervention — of which PTM-101 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06673017 reports 6 study locations spanning 5 distinct geographic areas — top geographies include Texas, California, Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06673017 about?

NCT06673017 is a clinical study titled "PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC)". This is a multi-center, non-randomized, single-arm, open-label, phase Ib, dose escalation/dose expansion study of PTM-101 when combined with neoadjuvant chemotherapy for the treatment of treatment-naïve subjects with borderline resectable and locally advanced pancreatic ductal adenocarcinoma (PDAC).

What is the current status of trial NCT06673017?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 26 participants. The study started on 2025-04-14. Estimated completion is 2028-06.

What conditions does trial NCT06673017 study?

This clinical trial studies the following conditions: Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma, Locally Advanced Pancreatic Adenocarcinoma, Borderline Resectable Pancreatic Adenocarcinoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06673017?

The interventions under investigation include: PTM-101 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06673017?

This trial is sponsored by PanTher Therapeutics, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06673017 being conducted?

This trial has 6 study locations across California, Michigan, New York, Texas, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial