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ClinicalTrials.gov 5 recruiting now official registry

Locally Advanced Pancreatic Ductal Adenocarcinoma clinical trials

5 of 8 indexed Locally Advanced Pancreatic Ductal Adenocarcinoma trials are currently recruiting.

8 US clinical trials · 5 currently recruiting

Locally Advanced Pancreatic Ductal Adenocarcinoma is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is OHSU Knight Cancer Institute, running 2 of these trials.

The research picture

Locally Advanced Pancreatic Ductal Adenocarcinoma has 8 registered US clinical trials, 5 of them open to new participants right now, about 63% of the total.

5
recruiting participants now
63%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: OHSU Knight Cancer Institute
Phase 16Phase 21

Active & Recent Trials

8 total, page 1 of 1

RECRUITING Early Phase 1 90 participants

Targeted Pathway Inhibition in Patients With Pancreatic Cancer

OHSU Knight Cancer Institute

NCT04005690

RECRUITING 70 participants

Hyperpolarized 13C MRI to Predict Response in Pancreatic Cancer

University of California, San Francisco

NCT06600906

RECRUITING Phase 1 56 participants

Zimberelimab and Quemliclustat in Combination With Chemotherapy for the Treatment of Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma

Jonsson Comprehensive Cancer Center

NCT05688215

RECRUITING Phase 1 36 participants

A Phase 1 Study to Evaluate Safety and Efficacy of XER-001 (Amifostine for Nasoduodenal Delivery) in Combination With Sterotactic Body Radiotherapy for Treatment in Patients With Locally Advanced Pancreatic Cancer.

Xerient Pharma

NCT07157033

RECRUITING Early Phase 1 12 participants

OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma

OHSU Knight Cancer Institute

NCT07089940

ACTIVE NOT RECRUITING Phase 1 120 participants

Sonoporation and Chemotherapy for the Treatment of Pancreatic Cancer

Flemming Forsberg

NCT04821284

ACTIVE NOT RECRUITING Phase 2 105 participants

New and Emerging Therapies for the Treatment of Resectable, Borderline Resectable, or Locally Advanced Pancreatic Cancer, PIONEER-Panc Study

M.D. Anderson Cancer Center

NCT04481204

ACTIVE NOT RECRUITING Phase 1 22 participants

Losartan and Hypofractionated Rx After Chemo for Tx of Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer (SHAPER)

University of Utah

NCT04106856

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Locally Advanced Pancreatic Ductal Adenocarcinoma Trial Landscape

8 indexed Locally Advanced Pancreatic Ductal Adenocarcinoma studies · 5 recruiting (63%).

Phase mix: 0 late (III/IV) vs 7 early (I/II).

Top sponsor: OHSU Knight Cancer Institute (2 trials), 6 others listed. 8 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Locally Advanced Pancreatic Ductal Adenocarcinoma?

PlainTrial tracks 8 US clinical trials for Locally Advanced Pancreatic Ductal Adenocarcinoma, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Locally Advanced Pancreatic Ductal Adenocarcinoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.