Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Have Previously Participated in a Clinical Study With PF-07868489
NCT07073820 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to learn about the long-term safety, tolerability and effects of the study medicine (PF-07868489) for the possible treatment of PAH. PAH is a condition in which there is high blood pressure in the arteries that carry blood from the heart to the lungs. This high pressure makes it harder for the heart to pump blood through those lungs, potentially damaging the right side of the heart. This is an open-label study. Which means that both the healthcare providers and the study participants are aware of the medicine being given. This study is also an extension study with study medicine (PF-07868489). An extension study allows patients from an earlier clinical study (also called as qualifying study) to continue participating to assess long-term benefits and safety of the medicine.
Conditions Studied
Interventions
- DRUG PF-07868489
Study Locations (20)
California
- UCSF Health St. Mary's Hospital — San Francisco
- Heart and Vascular Center — San Francisco
Kentucky
- Norton Hospital — Louisville
- Norton Pulmonary Specialists — Louisville
Rhode Island
- Rhode Island Hospital — Providence
- Center for Advanced Lung Care — Providence
Other
- HUB Hôpital Erasme — Brussels
- UZ Leuven — Leuven
Ontario
- London Health Sciences Centre - University Hospital — London
- London Health Sciences Centre — London
Colorado
- University of Colorado Anschutz Medical Campus — Aurora
New South Wales
- Royal Prince Alfred Hospital — Camperdown
Guangdong
- Guangdong Provincial People's Hospital — Guangzhou
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2025-11-10 |
| Est. Completion | 2028-07-18 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07073820
The ClinicalTrials.gov registry entry for NCT07073820 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pfizer, which has 769 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Pulmonary Hypertension appearing as the primary indexed condition, and to 1 intervention — of which PF-07868489 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT07073820 reports 20 study locations spanning 15 distinct geographic areas — top geographies include California, Kentucky, Rhode Island. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT07073820 about?
NCT07073820 is a clinical study titled "A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Have Previously Participated in a Clinical Study With PF-07868489". The purpose of this study is to learn about the long-term safety, tolerability and effects of the study medicine (PF-07868489) for the possible treatment of PAH. PAH is a condition in which there is high blood pressure in the arteries that carry blood from the heart to the lungs. This high pressure ...
What is the current status of trial NCT07073820?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 36 participants. The study started on 2025-11-10. Estimated completion is 2028-07-18.
What conditions does trial NCT07073820 study?
This clinical trial studies the following conditions: Pulmonary Hypertension. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT07073820?
The interventions under investigation include: PF-07868489 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT07073820?
This trial is sponsored by Pfizer, which has 769 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT07073820 being conducted?
This trial has 20 study locations across California, Colorado, Kentucky, Rhode Island, New South Wales. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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