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NCT03629340 · ClinicalTrials.gov registry record · Phase 2
Metformin for Pulmonary Hypertension HFpEF
A Phase 2 study of Heart Failure and Pulmonary Hypertension, sponsored by University of California, San Francisco.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 10
- Enrollment target
- 2
- Study locations
NCT03629340: Recruiting Phase 2 study of Heart Failure and Pulmonary Hypertension, sponsored by University of California, San Francisco.
NCT03629340 is a Phase 2 study of Heart Failure and Pulmonary Hypertension that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 10 participants, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (100% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03629340, a Phase 2 study of Heart Failure and Pulmonary Hypertension, is actively recruiting participants, sponsored by University of California, San Francisco.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 10 participants
- Enrollment target
- 2
- Study locations
Study Summary
The main objective of this study is to determine the clinical efficacy of metformin versus placebo and the therapeutic response with regards to functional capacity and hemodynamics in PH-HFpEF.
Conditions Studied
Interventions
- DRUG Metformin
- DRUG Placebo oral capsule
Study Locations (2)
California
- UCSF Medical Center - San Francisco
Pennsylvania
- University of Pittsburgh Medical Center - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2019-02-26 |
| Est. Completion | 2026-02 |
| Phase | Phase 2 |
What NCT03629340 shows while recruiting
NCT03629340 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with Heart Failure appearing as the primary indexed condition, and to 2 interventions - of which Metformin is the first listed.
NCT03629340 reports a single indexed study location in California, Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT03629340 about?
NCT03629340 is a clinical study titled "Metformin for Pulmonary Hypertension HFpEF". The main objective of this study is to determine the clinical efficacy of metformin versus placebo and the therapeutic response with regards to functional capacity and hemodynamics in PH-HFpEF.
What is the current status of trial NCT03629340?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 10 participants. The study started on 2019-02-26. Estimated completion is 2026-02.
What conditions does trial NCT03629340 study?
This clinical trial studies the following conditions: Heart Failure, Pulmonary Hypertension.
What interventions are being tested in trial NCT03629340?
The interventions under investigation include: Metformin (DRUG), Placebo oral capsule (DRUG).
Who is sponsoring clinical trial NCT03629340?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03629340 being conducted?
This trial has 2 study locations across California, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heart Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03629340's enrollment target sits among peer trials
10 383rd of 397 higher than 7 of 397 other Heart Failure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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