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NCT04991454 · ClinicalTrials.gov registry record · Phase 2
Xenon MRI Pulm Hypertension
A Phase 2 study of Pulmonary Hypertension and Pulmonary Arterial Hypertension, sponsored by Bastiaan Driehuys.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT04991454 is a Phase 2 study of Pulmonary Hypertension and Pulmonary Arterial Hypertension that is actively recruiting participants, run by Bastiaan Driehuys. The registered enrollment target is 60 participants, below the 613-participant average among 72 other Pulmonary Hypertension trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04991454, a Phase 2 study of Pulmonary Hypertension and Pulmonary Arterial Hypertension, is actively recruiting participants, sponsored by Bastiaan Driehuys.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The overall objective outlined in this study is to determine how pulmonary vascular remodeling in PAH at a cellular and pathological level is associated with changes in gas exchange physiology and hemodynamics (monitored with 129Xe MRI/MRS) and how these signals change with disease progression or treatment.
Conditions Studied
Interventions
- DRUG 129Xe Hyperpolarized
Study Locations (1)
North Carolina
- Duke University Medical Center - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2021-09-01 |
| Est. Completion | 2026-08-30 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04991454
The ClinicalTrials.gov registry entry for NCT04991454 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 613-participant average among 72 other Pulmonary Hypertension trials with a reported enrollment target (90% lower). The listed sponsor is Bastiaan Driehuys, which has 16 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Pulmonary Hypertension appearing as the primary indexed condition, and to 1 intervention - of which 129Xe Hyperpolarized is the first listed.
NCT04991454 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.
Frequently Asked Questions
What is clinical trial NCT04991454 about?
NCT04991454 is a clinical study titled "Xenon MRI Pulm Hypertension". The overall objective outlined in this study is to determine how pulmonary vascular remodeling in PAH at a cellular and pathological level is associated with changes in gas exchange physiology and hemodynamics (monitored with 129Xe MRI/MRS) and how these signals change with disease progression or tr...
What is the current status of trial NCT04991454?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2021-09-01. Estimated completion is 2026-08-30.
What conditions does trial NCT04991454 study?
This clinical trial studies the following conditions: Pulmonary Hypertension, Pulmonary Arterial Hypertension.
What interventions are being tested in trial NCT04991454?
The interventions under investigation include: 129Xe Hyperpolarized (DRUG).
Who is sponsoring clinical trial NCT04991454?
This trial is sponsored by Bastiaan Driehuys, which has 16 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04991454 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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