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ClinicalTrials.gov 4 recruiting now later-stage tilt small index

Sedation: later-stage trial registry

4 of 13 indexed Sedation trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · 4 currently recruiting · #1,315 of 28,707 conditions by registered trial count

Sedation: 13 US clinical trials tracked, 4 recruiting.

Sedation is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Sedana Medical, running 3 of these trials.

Enrollment posture brief

Registry condition sedation

OPEN 4 | RECR 31% | LATE 7 | EARLY 2 | RANK #1315 | SPON 3

Nearest open-share peer: Acute Decompensated Heart Failure (31% recruiting · 13 trials)

ACL Injury61.5%Acute Biphenotypic Leukemia46.2%Sedation (this)31%Accidental Falls30.8%Actinic Keratoses23.1%
Open-enrollment share among volume-matched conditions near Sedation

Sedation lists 4 open slots (31% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Sedation on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Sedation is recruiting below its size-band peers.

    4 of 13 indexed trials (30.8%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Sedation research.

    Sedana Medical accounts for 3 of 13 trials (23.1%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical Sedation enrolment sits around 126 participants.

    Median target enrolment is 126 among the 13 trials that report a genuine target (sentinel values excluded). 4 of those (30.8%) plan for fewer than 100 participants.

  4. Sedation research is mostly interventional.

    11 interventional and 2 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 21Phase 34Phase 43

Open and recent trials

13 total, page 1 of 1

RECRUITING 1,200,000 participants

The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes

Massachusetts General Hospital

NCT07022951

RECRUITING NA 100 participants

Neurosteer Bedside Monitoring System

Icahn School of Medicine at Mount Sinai

NCT06718764

RECRUITING Phase 3 100 participants

Sedation During Endoscopy Using Remimazolam: Efficacy in a Novel Exploration

Massachusetts General Hospital

NCT07269808

RECRUITING Phase 4 20 participants

Oral vs IV Sedation for Cataract Surgery in Older Adults

University of California, San Francisco

NCT07154147

ACTIVE NOT RECRUITING Phase 3 312 participants

A Pooled Analysis of Long-Term Outcomes After Inhaled Isoflurane Via the Sedaconda ACD-S Compared to Intravenous Propofol

Sedana Medical

NCT06809218

ACTIVE NOT RECRUITING Early Phase 1 276 participants

Evaluation of Ketamine/Midazolam Sedation vs. Fentanyl/Midazolam Sedation for Image-Guided Percutaneous Procedures in Interventional Radiology

CAMC Health System

NCT07040163

ACTIVE NOT RECRUITING Phase 3 235 participants

Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU1)

Sedana Medical

NCT05312385

COMPLETED 680 participants

Implementation of an Analgesia-sedation Algorithm in the Pediatric ICU to Reduce Benzodiazepine Use

Boston Children's Hospital

NCT04263662

COMPLETED Phase 3 282 participants

Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU2)

Sedana Medical

NCT05327296

COMPLETED Phase 4 126 participants

Propofol Versus Alfentanil Versus Nitrous Oxide for Moderate Procedural Sedation

Hennepin Healthcare Research Institute

NCT00997126

COMPLETED Phase 4 50 participants

Alternative Sedation During Bronchoscopy

University of Pennsylvania

NCT01158820

COMPLETED Phase 2 35 participants

Acute Neurological ICU Sedation Trial (ANIST)

Johns Hopkins University

NCT00390871

COMPLETED NA 12 participants

Use of Dexmedetomidine for Sedation During Flexible Bronchoscopy in Patients With COPD: A Descriptive Study

The Cooper Health System

NCT00401206

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1
Phase 3 4
Phase 4 3

Named interventions

Most-linked intervention names on Sedation records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Propofol Drug
4 trials
Isoflurane Drug
2 trials
Midazolam Drug
2 trials
Analgesia-Sedation algorithm Other
1 trials
dexmedetomidine Drug
1 trials
Fentanyl/Propofol Drug
1 trials
Fentanyl/Dexmedetomidine Drug
1 trials
Alfentanil Drug
1 trials

US sites by state

Facility locations filed on Sedation trials. A trial with sites in several states counts in each.

Massachusetts 5 trials
Virginia 2 trials
Texas 2 trials
Tennessee 2 trials
Pennsylvania 2 trials
Ohio 2 trials
New York 2 trials
New Jersey 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Sedation page

13 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Sedation condition card totals 13 registered trials; most-linked intervention Propofol; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.