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ClinicalTrials.gov 4 recruiting now official registry

Sedation clinical trials

4 of 13 indexed Sedation trials are currently recruiting.

13 US clinical trials · 4 currently recruiting

Sedation is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Sedana Medical, running 3 of these trials.

The research picture

Sedation has 13 registered US clinical trials, 4 of them open to new participants right now, about 31% of the total.

4
recruiting participants now
31%
of trials open to enrollment
7
in Phase 3–4 (later-stage)
3
top sponsor: Sedana Medical
Phase 11Phase 21Phase 34Phase 43

Active & Recent Trials

13 total, page 1 of 1

RECRUITING 1,200,000 participants

The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes

Massachusetts General Hospital

NCT07022951

RECRUITING NA 100 participants

Neurosteer Bedside Monitoring System

Icahn School of Medicine at Mount Sinai

NCT06718764

RECRUITING Phase 3 100 participants

Sedation During Endoscopy Using Remimazolam: Efficacy in a Novel Exploration

Massachusetts General Hospital

NCT07269808

RECRUITING Phase 4 20 participants

Oral vs IV Sedation for Cataract Surgery in Older Adults

University of California, San Francisco

NCT07154147

ACTIVE NOT RECRUITING Phase 3 312 participants

A Pooled Analysis of Long-Term Outcomes After Inhaled Isoflurane Via the Sedaconda ACD-S Compared to Intravenous Propofol

Sedana Medical

NCT06809218

ACTIVE NOT RECRUITING Early Phase 1 276 participants

Evaluation of Ketamine/Midazolam Sedation vs. Fentanyl/Midazolam Sedation for Image-Guided Percutaneous Procedures in Interventional Radiology

CAMC Health System

NCT07040163

ACTIVE NOT RECRUITING Phase 3 235 participants

Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU1)

Sedana Medical

NCT05312385

COMPLETED 680 participants

Implementation of an Analgesia-sedation Algorithm in the Pediatric ICU to Reduce Benzodiazepine Use

Boston Children's Hospital

NCT04263662

COMPLETED Phase 3 282 participants

Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU2)

Sedana Medical

NCT05327296

COMPLETED Phase 4 126 participants

Propofol Versus Alfentanil Versus Nitrous Oxide for Moderate Procedural Sedation

Hennepin Healthcare Research Institute

NCT00997126

COMPLETED Phase 4 50 participants

Alternative Sedation During Bronchoscopy

University of Pennsylvania

NCT01158820

COMPLETED Phase 2 35 participants

Acute Neurological ICU Sedation Trial (ANIST)

Johns Hopkins University

NCT00390871

COMPLETED NA 12 participants

Use of Dexmedetomidine for Sedation During Flexible Bronchoscopy in Patients With COPD: A Descriptive Study

The Cooper Health System

NCT00401206

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1
Phase 3 4
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Sedation Trial Landscape

13 indexed Sedation studies · 4 recruiting (31%).

Phase mix: 7 late (III/IV) vs 2 early (I/II).

Top sponsor: Sedana Medical (3 trials), 9 others listed. 13 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Sedation?

PlainTrial tracks 13 US clinical trials for Sedation, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Sedation?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.