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NCT06029933 · ClinicalTrials.gov registry record

Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years

A clinical trial of Influenza and Community-acquired Pneumonia, sponsored by Kaiser Permanente.

Recruiting
Registry status
960,000
Enrollment target
1
Study location

NCT06029933 is a study of Influenza and Community-acquired Pneumonia that is actively recruiting participants, run by Kaiser Permanente. The registered enrollment target is 960,000 participants, above the 30,650-participant average among 156 other Influenza trials with a reported enrollment target (3032% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT06029933, a study of Influenza and Community-acquired Pneumonia, is actively recruiting participants, sponsored by Kaiser Permanente.

RECRUITING
Registry status
960,000 participants
Enrollment target
1
Study location

Study Summary

This study will evaluate the relative vaccine effectiveness of quadrivalent adjuvanted inactivated influenza vaccine (aIIV4) versus quadrivalent high-dose inactivated influenza vaccine (HD-IIV4) in preventing polymerase chain reaction (PCR)-confirmed influenza and influenza-related outcomes in adults ≥65 years of age during the 2023/24 and 2024/25 influenza seasons. The study is an observational study conducted at Kaiser Permanente Northern California (KPNC), an integrated health care system in the United States.

Interventions

  • BIOLOGICAL Adjuvanted Quadrivalent Inactivated Influenza Vaccine (aIIV4)
  • BIOLOGICAL High-Dose Quadrivalent Inactivated Influenza Vaccine (HD-IIV4)

Study Locations (1)

California

  • Kaiser Permanente Northern California (entire region) - Oakland

Trial Details

FieldValue
Enrollment Target 960,000 participants
Start Date 2023-08-17
Est. Completion 2026-05

Sponsor

Kaiser Permanente

294 total trials

What the Registry Record Tells You About NCT06029933

The ClinicalTrials.gov registry entry for NCT06029933 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 960,000 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 30,650-participant average among 156 other Influenza trials with a reported enrollment target (3032% higher). The listed sponsor is Kaiser Permanente, which has 294 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Influenza appearing as the primary indexed condition, and to 2 interventions - of which Adjuvanted Quadrivalent Inactivated Influenza Vaccine (aIIV4) is the first listed.

NCT06029933 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT06029933 about?

NCT06029933 is a clinical study titled "Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years". This study will evaluate the relative vaccine effectiveness of quadrivalent adjuvanted inactivated influenza vaccine (aIIV4) versus quadrivalent high-dose inactivated influenza vaccine (HD-IIV4) in preventing polymerase chain reaction (PCR)-confirmed influenza and influenza-related outcomes in adult...

What is the current status of trial NCT06029933?

This trial is currently recruiting. The enrollment target is 960,000 participants. The study started on 2023-08-17. Estimated completion is 2026-05.

What conditions does trial NCT06029933 study?

This clinical trial studies the following conditions: Influenza, Community-acquired Pneumonia, Cardiovascular Events.

What interventions are being tested in trial NCT06029933?

The interventions under investigation include: Adjuvanted Quadrivalent Inactivated Influenza Vaccine (aIIV4) (BIOLOGICAL), High-Dose Quadrivalent Inactivated Influenza Vaccine (HD-IIV4) (BIOLOGICAL).

Who is sponsoring clinical trial NCT06029933?

This trial is sponsored by Kaiser Permanente, which has 294 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06029933 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.